L-745,870 TRIHYDROCHLORIDE

Product Name: L-745,870 TRIHYDROCHLORIDE
CAS No.: 158985-00-3
Chemical Name: L-745,870 TRIHYDROCHLORIDE
Synonyms: 3HCl;L 745870;L 745870,L745870;L-745,870 trihydroch;L-745,870 TRIHYDROCHLORIDE;3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-;3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE
CBNumber: CB6481216
Molecular Formula: C18H19ClN4
Formula Weight: 326.82
MOL File: 158985-00-3.mol

More

Less

L-745,870 TRIHYDROCHLORIDE Property

Boiling point:: 571.4±50.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Desiccate at +4°C
solubility: DMSO:16.5(Max Conc. mg/mL);50.49(Max Conc. mM)
pka: 8.20±0.20(Predicted)
form: Solid
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 1002
Product name: L-745,870trihydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $634
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 10MG
Price: $665.81
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 50MG
Price: $1073.29
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 1G
Price: $1529.85
Updated: 2021/12/16

ChemScene

Product number: CS-0003281
Product name: L-745870
Purity: 99.88%
Packaging: 5mg
Price: $82
Updated: 2021/12/16

More

Less

L-745,870 TRIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

L-745,870 is a drug which acts as a dopamine receptor antagonist selective for the D4 subtype, and has antipsychotic effects in animal models, though it was not effective in human trials.

Definition

ChEBI: 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine is a member of piperazines.

Biological Activity

A highly potent and selective D 4 dopamine receptor antagonist; L-745,870 has K i values of 0.51, 2300 and 960 nM for D 4 , D 3 and D 2 subtypes respectively and > 1000-fold selectivity over 5-HT 2 , D 1 and D 5 receptors.

L-745,870 TRIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

L-745,870 TRIHYDROCHLORIDE Suppliers

China 27 Germany 1 Japan 2 United Kingdom 3 United States 7 Global 40

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: +86 (21) 5895-8628
Email: sales@uhnshanghai.com
Country: China
ProdList: 977
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4597
Advantage: 55

MQ (shanghai) Pharmaceuticals Co., Ltd.

Tel: 13761635123
Fax: 1014988033@qq
Email: 1014988033@qq.com
Country: China
ProdList: 4997
Advantage: 55

cjbscvictory

Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10011
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

Beijing Stronger Science Co., Ltd.

Tel: 0531-88924771 15614660963
Email: elsa.hang@strongerscience.com
Country: China
ProdList: 10623
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 7999
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 13774214275
Email: zhouzz@univ-bio.com
Country: China
ProdList: 24994
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62075
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 10020
Advantage: 58

Suzhou Zhixin Biotechnology Co., Ltd.

Tel: 0512-65118909 15162312715
Email: sales@szzxbio.com
Country: China
ProdList: 3003
Advantage: 58

Suzhou Meishi Biotechnology Co., Ltd.

Tel: 1173954148q
Email: meishipharma@126.com
Country: China
ProdList: 20033
Advantage: 58

Shandong Mopai Biotechnology Co., Ltd

Tel: 13070690626
Email: admin@mopaikeji.com
Country: China
ProdList: 10757
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9266
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

Tel: 13915962545
Email: 2881759498@qq.com
Country: China
ProdList: 3660
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 32957
Advantage: 60

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43340
Advantage: 58

Zibo Hangyu Biotechnology Development Co., Ltd

Tel: +86-0533-2185556 +8617865335152
Email: Mandy@hangyubiotech.com
Country: China
ProdList: 10986
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Shanghai Yubo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 344843571@qq.com
Country: CHINA
ProdList: 6318
Advantage: 58

Zhongsheng Huamei (Beijing) Technology Co., Ltd.

Tel: --
Fax: --
Email: hanye@huameibio.com
Country: CHINA
ProdList: 5
Advantage: 58

Shanghai Yanhua Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: yanhuibio@163.com
Country: CHINA
ProdList: 4380
Advantage: 58

Shanghai Yuda Industrial Co., Ltd.

Tel: --
Fax: --
Email: lucy@runwelltac.com
Country: CHINA
ProdList: 6105
Advantage: 58

158985-00-3, L-745,870 TRIHYDROCHLORIDERelated Search:

hypochlorous acid 1-(2,9-diazabicyclo[4.3.0]nona-2,4,7,10-tetraen-7-yl)-N,N-dimethyl-methanamine 1-(4-Chlorophenyl)piperazine dihydrochloride 1H-Pyrrolo[2,3-b]pyridine, 3-(1-piperazinylmethyl)- 3-METHYL-7-AZAINDOLE 3-([4-(4-CHLOROPHENYL)PIPERAZIN-1-YL]METHYL)-1H-PYRROLO(2,3-B)PYRIDINE HYDROCHLORIDE 7-Azaindole L-745,870 TRIHYDROCHLORIDE

L-745,870 TRIHYDROCHLORIDE

3HCl

3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE

L 745870

3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine

1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-

L-745,870 trihydroch

L 745870,L745870

158985-00-3

C18H22Cl4N4

C18H19N4Cl3HCl