ChemicalBook > CAS DataBase List > AC-DEVD-CHO

AC-DEVD-CHO

Product Name
AC-DEVD-CHO
CAS No.
169332-60-9
Chemical Name
AC-DEVD-CHO
Synonyms
MF 191;AC-DEVD-CHO;AC-DEVD-ALDEHYDE;AC-DEVD-CHO?, >98%;CASPASE-3 INHIBITOR;ACETYL-DEVD-ALDEHYDE;Ac-Asp-Glu-Val-Asp-H;CASPASE-3 INHIBITOR I;AC-DEVD-CHO USP/EP/BP;AcDEVDCHO,Ac DEVD CHO
CBNumber
CB6488321
Molecular Formula
C20H30N4O11
Formula Weight
502.47
MOL File
169332-60-9.mol
More
Less

AC-DEVD-CHO Property

Boiling point:
1021.1±65.0 °C(Predicted)
Density 
1.374±0.06 g/cm3(Predicted)
RTECS 
EK7643000
storage temp. 
-20°C
solubility 
H2O: 1 mg/mL
form 
powder
pka
4.19±0.10(Predicted)
color 
white
Sensitive 
Moisture Sensitive
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
235420
Product name
Caspase-3 Inhibitor I
Packaging
1mg
Price
$113
Updated
2024/03/01
Sigma-Aldrich
Product number
235420
Product name
Caspase-3 Inhibitor I
Packaging
5mg
Price
$475
Updated
2024/03/01
Alfa Aesar
Product number
J65204
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Packaging
5mg
Price
$401
Updated
2023/06/20
Alfa Aesar
Product number
J65204
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Packaging
1mg
Price
$101
Updated
2021/12/16
Sigma-Aldrich
Product number
A0835
Product name
N-Acetyl-Asp-Glu-Val-Asp-al
Purity
≥95%, powder
Packaging
1mg
Price
$161
Updated
2024/03/01
More
Less

AC-DEVD-CHO Chemical Properties,Usage,Production

Uses

Reversible inhibitor of interleukin-1beta converting enzyme (ICE); also inhibits caspase-3 cleavage of poly(ADP-ribose) polymerase

Uses

N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.

Definition

ChEBI: A tetrapeptide consisting of two L-aspartic acid residues, an L-glutamyl residue and an L-valine residue with an acetyl group at the N-terminal and with the C-terminal carboxy group reduced to an aldehyde. It is an inhibitor of caspase-3/7.

General Description

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.

Biochem/physiol Actions

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.

AC-DEVD-CHO Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

AC-DEVD-CHO Suppliers

China 55 India 1 Switzerland 1 United Kingdom 2 United States 14 Global 73
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3421
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12308
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
eric@peptidego.com
Country
China
ProdList
6347
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9730
Advantage
58
Guangzhou Tomums Life Science Co., Ltd.
Tel
020-31155029 18902330969
Fax
020-31155029
Email
sales@tomums.cn
Country
China
ProdList
4698
Advantage
58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1991
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19915
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
28914
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658; 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
10005
Advantage
58
Shanghai Lanle Bird Industrial Co., Ltd.
Tel
15021845385
Email
765325601@qq.com
Country
China
ProdList
3611
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28180
Advantage
58
Shanghai Kanglang Biotechnology Co., Ltd.
Tel
021-61998208 18217752821
Fax
021-37680378
Email
sales@klbio.cn
Country
China
ProdList
9617
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
chenjw@absin.cn
Country
China
ProdList
24734
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
Beijing Aomi Jiade Pharmaceutical Technology Co., Ltd
Tel
13522808617
Email
omiget@qq.com
Country
China
ProdList
9213
Advantage
58
Ontores Biotech
Tel
0571-88760729 18072970094
Email
supports@ontorespeptide.com
Country
China
ProdList
2696
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921 13355716090
Email
Sales@gotopbio.com
Country
China
ProdList
2831
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
DONBOO AMINO ACID COMPANY
Tel
+8613063595538
Email
donboo@donboo.com
Country
China
ProdList
9365
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
29778
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
18768175414
Email
gaojun@univ-bio.com
Country
China
ProdList
24998
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Email
product02@bidepharm.com
Country
China
ProdList
61720
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6712
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-88211921 15572296305
Email
sales4@gotopbio.com
Country
China
ProdList
5144
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24131
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
5950
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
278
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169097
Email
market03@meryer.com
Country
China
ProdList
27996
Advantage
58
Shanghai HongTide Biotechnology Co.,Ltd.
Tel
19961912513
Email
sales@hongtide.com
Country
China
ProdList
4531
Advantage
58
Combio (Suzhou) Ltd.
Tel
0512-51886999 17706251929
Email
office@combiosz.com
Country
China
ProdList
2224
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50751
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29989
Advantage
58
Beijing Boorsen Biotechnology Co., Ltd
Tel
400-901-9800 18611424007
Email
cis@bioss.com.cn
Country
China
ProdList
9518
Advantage
58
Zhejiang Jiekun Biotechnology Co., Ltd
Tel
0571-88211951 13735575465
Email
sales1@gotopbio.com
Country
China
ProdList
4904
Advantage
58
Taiyuan Bailihengkang Biotechnology Co., Ltd
Tel
19135651983 19135651983
Email
18611134419@163.com
Country
China
ProdList
4976
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48570
Advantage
58
Hangzhou Beiputai Biopharmaceutical Co., Ltd
Tel
0571-85350119 13305819357
Email
bptsales@163.com
Country
China
ProdList
3579
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
sales@ubiochem.com
Country
China
ProdList
9146
Advantage
58
Shenzhen Nexconn Pharmatechs Ltd
Tel
+86-755-89396905 +86-15013857715
Email
admin@nexconn.com
Country
China
ProdList
10248
Advantage
58

169332-60-9, AC-DEVD-CHORelated Search:

AC-IETD-CHO N-acetyl aspartyl-glutaMic acid AC-DEVD-CHO BIOTIN-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE AC-DEVD-AMC ORCOKININ AC-DEVD-AFC AC-DEVD-CHO BIOTIN-DEVD-CHO MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH AC-DEVD-PNA CYCLIC ADIPOYL-(6-AMINO)HEXANOYL-DEVD-RHODAMINE 110, TRIETHYLAMINE SALT BIOTIN-X-DEVD-FMK (7-METHOXYCOUMARIN-4-YL)ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPARTYL-L-ALANYL-L-PROLYL-N-EPSILON-(2,4-DINITROPHENYL)-L-LYSINE AMIDE AC-ASP-GLU-VAL-ASP-BETA-NA BIOTINYL-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE ANTI-IP3 RECEPTOR TYPE I NEUTRALIZING PEPTIDE AC-ASP-GLU-VAL-ASP-CHO TFA

  • Ac-DEVD-CHO,N-Acetyl-Asp-Glu-Val-Asp-al, >98%
  • AC-DEVD-CHO?, >98%
  • Caspase-3 Inhibitor I - CAS 169332-60-9 - Calbiochem
  • N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-(2-CARBOXY-1-FORMYLETHYL)-L VALINAMIDE
  • N-AC-ASP-GLU-VAL-ASP-CHO
  • N-ACETYL-ASP-GLU-VAL-ASP-AL
  • N-ACETYL-ASP-GLU-VAL-ASP-CHO (ALDEHYDE)
  • CPP32/APOPAIN INHIBITOR
  • CASPASE-3 INHIBITOR I
  • CASPASE-3 INHIBITOR (ALDEHYDE)
  • ACETYL-DEVD-ALDEHYDE
  • ACETYL-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPART-1-AL
  • ACETYL-ASP-GLU-VAL-ASP-ALDEHYDE
  • AC-DEVD-CHO
  • AC-DEVD-ALDEHYDE
  • AC-ASP-GLU-VAL-ASP-ALDEHYDE
  • AC-ASP-GLU-VAL-ASP-ALDEHYDE (PSEUDO ACID)
  • AC-ASP-GLU-VAL-ASP-H (ALDEHYDE)
  • AC-ASP-GLU-VAL-ASP-CHO
  • Acetyl-aspartyl-glutamyl-valyl-aspartal
  • CASPASE-3 INHIBITOR
  • CASPASE 3 (APOPAIN) INHIBITOR 1
  • MF 191
  • N-acetyl-Asp-Glu-Val-Asp-Ala
  • (4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxyMethyl)-13-forMyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
  • Ac-Asp-Glu-Val-Asp-H
  • CASPASE-3 INHIBITOR I;N-AC-ASP-GLU-VAL-ASP-CHO;ACETYL-ASPARTYL-GLUTAMYL-VALYL-ASPARTAL
  • L-Valinamide, N-acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-
  • N-Acetyl-Asp-Glu-Val-Asp-al >=95%, powder
  • AC-DEVD-CHO USP/EP/BP
  • Ac-DEVD-CHO，N-Acetyl-Asp-Glu-Val-Asp-al
  • Caspase 3 Inhibitor I,Caspase3 Inhibitor I
  • AcDEVDCHO,Ac DEVD CHO
  • 169332-60-9
  • Caspase 10
  • Caspases
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Apoptosis and Cell Cycle
  • BioChemical
  • Inhibitors
  • peptides
  • Caspase 10
  • Caspase 3
  • Caspase 7
  • Caspase 8
  • Caspase Inhibitors
  • Caspase Inhibitors and Substrates
  • Peptides and Proteins
  • Peptides for Cell Biology
  • Protease Inhibitor Specificity Index
  • Protease Inhibitors
  • A to C
  • A-AM
  • Aldehydes
  • and Substrates
  • Apoptosis and Cell Cycle
  • Apoptosis Enzymes