Ceftibuten dihydrate

ChemicalBook > CAS DataBase List > Ceftibuten dihydrate

Product Name: Ceftibuten dihydrate
CAS No.: 118081-34-8
Chemical Name: Ceftibuten dihydrate
Synonyms: Cetb;Cedax;Seftem;D02121;Sch-39720;Cedax (tn);Cedax-13C3;Seftem (tn);S 7432-13C3;Cedax dihydrate
CBNumber: CB6496825
Molecular Formula: C15H16N4O7S2
Formula Weight: 428.43
MOL File: 118081-34-8.mol

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Ceftibuten dihydrate Property

Melting point:: >180°C (dec.)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO (Slightly), Water (Slightly)
form: Solid
color: Pale Yellow to Light Orange
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P235Keep cool.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25334
Product name: Ceftibuten (hydrate)
Purity: ≥98%
Packaging: 10mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 25334
Product name: Ceftibuten (hydrate)
Purity: ≥98%
Packaging: 25mg
Price: $188
Updated: 2024/03/01

Cayman Chemical

Product number: 25334
Product name: Ceftibuten (hydrate)
Purity: ≥98%
Packaging: 50mg
Price: $356
Updated: 2024/03/01

Cayman Chemical

Product number: 25334
Product name: Ceftibuten (hydrate)
Purity: ≥98%
Packaging: 100mg
Price: $672
Updated: 2024/03/01

TRC

Product number: C244500
Product name: Ceftibuten Hydrate
Packaging: 2g
Price: $1755
Updated: 2021/12/16

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Ceftibuten dihydrate Chemical Properties,Usage,Production

Chemical Properties

Light-Yellow Solid

Uses

Ceftibuten dihydrate, one of the third-generation cephalosporin antibiotic is effectively used in curing several infectious diseases.

Uses

Ceftibuten Dihydrate is used in preparation of Ceftibuten crystal.

Definition

ChEBI: Ceftibuten dihydrate is the dihydrate of ceftibuten. It is used as an orally administered treatment for urinary-tract and respiratory-tract infections. It has a role as an antibacterial drug. It contains a ceftibuten.

Biological Activity

Ceftibuten is an orally bioavailable broad-spectrum cephalosporin antibiotic that inhibits the growth of B. catarrhalis, H. influenzae, pathogenic Neisseria, Streptococcus, penicillin-susceptible S. pneumoniae, and eleven Enterobacteriaceae strains (MICs = 0.25, ≤0.06, ≤0.06, 0.5-1, 4, and ≤0.06-0.5 μg/ml, respectively).1,2 Ceftibuten is also active against E. coli expressing β-lactamase type I, III, and V and K. oxytoca expressing β-lactamase type IV (MICs = 8, 0.25, 0.5, and ≤0.06 μg/ml, respectively) as well as a panel of eight bacterial stains expressing plasmid-encoded extended spectrum β-lactamases, including E. coli CTX-M and K. pneumoniae SHV-2 (MICs = 1 and 0.25 μg/ml, respectively). In vivo, ceftibuten reduces the number of mice killed within 6 days of a K. pneumoniae, E. coli, S. pneumoniae, or S. aureus infection by 50% when administered subcutaneously at doses of 0.125, 2, 1,024, and >512 mg/kg, respectively.3 Formulations containing ceftibuten have been used in the treatment of bacterial infections including bronchitis, pneumonia, and enteritis.

Pharmacokinetics

Ceftibuten Dihydrate is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Ceftibuten binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Ceftibuten dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ceftibuten dihydrate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Ceftibuten dihydrate 118081-34-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-18

Hebei Zhanyao Biotechnology Co. Ltd

Product: Ceftibuten dihydrate 118081-34-8
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-11-12

Shaanxi Dideu Medichem Co. Ltd

Product: Ceftibuten dihydrate 118081-34-8
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 300 MT
Release date: 2020-05-23

118081-34-8, Ceftibuten dihydrateRelated Search:

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Cedax dihydrate

CEDAX DIHYDRATE;SCH-39720 DIHYDRATE

Sch-39720 dihydrate

(+)-(6r,7r)-7-[2-(2-amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate

Cedax

Cedax (tn)

Ceftibuten (jp15)

Cetb

D02121

Seftem

Seftem (tn)

Sch-39720

Cephalosporins cloth temple

Ceftibuten Hydrate

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[2-(2-aMino-4-thiazolyl)-4-carboxy-1-oxo-2-butenyl]aMino]-8-oxo-,dihydrate, [6R-[6a,7b(Z)]]- (9CI)

[6R-[6α,7β(Z)]]-7-[[2-(2-AMino-4-thiazolyl)-4-carboxy-1-oxo-2-butenyl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Dihydrate

[6R-[6α,7β(Z)]]-7-[[2-(2-AMino-4-thiazolyl)-4-carboxy-1-oxo-2-(butenyl-13C3)]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

Cedax-13C3

Cephalosporin 7432-S-13C3

S 7432-13C3

Ceftibuten 2-hydrate

ceftibuten dihydrate

(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-Yl)-4-Carboxybut-2-Enoylamino]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid Dihydrate

Ceftibuten dehydrate

(6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-4-carboxybut-2-enamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate

Ceftibuten dihydrate USP/EP/BP

Ceftibuten dihydrateQ: What is Ceftibuten dihydrate Q: What is the CAS Number of Ceftibuten dihydrate Q: What is the storage condition of Ceftibuten dihydrate Q: What are the applications of Ceftibuten dihydrate

Ceftibuten dihydrate Powder USP Standard

Cefobuxene dihydrate

118081-34-8

118081-34-1

C15H14N4O6S22H2O

C15H18N4O8S2

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