2-FLUORO-5-NITROBENZYL ALCOHOL 96

Product Name: 2-FLUORO-5-NITROBENZYL ALCOHOL 96
CAS No.: 63878-73-9
Chemical Name: 2-FLUORO-5-NITROBENZYL ALCOHOL 96
Synonyms: 2-Fluoro-5-nitrophenyl alcohol;2-Fluoro-5-nitronbenzyl alcohol;2-Fluoro-5-nitrobenzenemethanol;(2-Fluoro-5-nitrophenyl)methanol;2-Fluoro-5-nitrobenzyl alcohol 96%;2-FLUORO-5-NITROBENZYL ALCOHOL 96;Benzenemethanol, 2-fluoro-5-nitro-;2-Fluoro-5-nitrobenzyl alcohol 95+%
CBNumber: CB6504540
Molecular Formula: C7H6FNO3
Formula Weight: 171.13
MOL File: 63878-73-9.mol

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2-FLUORO-5-NITROBENZYL ALCOHOL 96 Property

Melting point:: 68-71 °C (lit.)
Boiling point:: 319.0±27.0 °C(Predicted)
Density: 1.434±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 13.34±0.10(Predicted)
Appearance: Yellow to brown Solid

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2906290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F597660
Product name: (2-Fluoro-5-nitrophenyl)methanol
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: F597660
Product name: (2-Fluoro-5-nitrophenyl)methanol
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 054228
Product name: (2-Fluoro-5-nitrophenyl)methanol
Purity: >95%
Packaging: 5g
Price: $346
Updated: 2021/12/16

Matrix Scientific

Product number: 054228
Product name: (2-Fluoro-5-nitrophenyl)methanol
Purity: >95%
Packaging: 1g
Price: $151
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4654-3-Z2
Product name: 2-Fluoro-5-nitrobenzyl alcohol
Purity: 95.0%
Packaging: 10g
Price: $194
Updated: 2021/12/16

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2-FLUORO-5-NITROBENZYL ALCOHOL 96 Chemical Properties,Usage,Production

Uses

2-Fluoro-5-nitrobenzyl alcohol may be used to synthesize 2-fluoro-5-nitrobenzyl bromide and 5-amino-2-fluorobenzyl alcohol.

General Description

2-Fluoro-5-nitrobenzyl alcohol can be prepared from 2-fluoro-5-nitrobenzaldehyde.

Synthesis

27996-87-8

63878-73-9

General steps for the synthesis of 2-fluoro-5-nitrobenzyl alcohol from 2-fluoro-5-nitrobenzaldehyde: Step A: Preparation of (2-fluoro-5-nitrobenzyl)methanol To a solution of 2-fluoro-5-nitrobenzaldehyde (1000 mg, 5.91 mmol) in methanol (10 mL) was added sodium borohydride (182 mg, 4.82 mmol). The reaction mixture was stirred at 0 °C for 3 hours. Upon completion of the reaction, the reaction mixture was acidified to pH 4 with 1 M hydrochloric acid and then concentrated. 50 mL of water was added and the product was extracted with ether. The organic layer was dried with magnesium sulfate, filtered and the solvent was evaporated. The target compound (2-fluoro-5-nitrophenyl)methanol was obtained as a light yellow solid (1007 mg, 99% yield) with a melting point of 62-64 °C. 1H NMR (300 MHz, CDCl3) δ 8.43 (dd, 6-CH, J = 6.2 Hz and 2.9 Hz, 1H), 8.19 (ddd, J = 9 Hz, 4.5 Hz and 2.9 Hz, 1H), 7.20 (dd, J = 9.0 Hz and 9.0 Hz, 1H), 4.85 (d, J = 3.6 Hz, 2H), 2.12 (s, 1H). 13C NMR (75 MHz, CDCl3) δ 125.0 (CH, d, J = 10.0 Hz), 124.7 (CH, d, J = 6.9 Hz), 116.2 (CH, d, J = 23.6 Hz), 58.2 (CH2).

References

[1] Heterocyclic Communications, 2010, vol. 16, # 4-6, p. 235 - 239
[2] Patent: WO2011/73322, 2011, A1. Location in patent: Page/Page column 48
[3] Patent: US2017/369489, 2017, A1. Location in patent: Paragraph 0453; 0465
[4] Journal of Heterocyclic Chemistry, 2008, vol. 45, # 2, p. 547 - 550
[5] Chemistry - A European Journal, 2015, vol. 21, # 32, p. 11462 - 11474

2-FLUORO-5-NITROBENZYL ALCOHOL 96 Preparation Products And Raw materials

Raw materials

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2-FLUORO-5-NITROBENZYL ALCOHOL 96 Suppliers

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63878-73-9, 2-FLUORO-5-NITROBENZYL ALCOHOL 96Related Search:

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2-FLUORO-5-NITROBENZYL ALCOHOL 96

(2-Fluoro-5-nitrophenyl)methanol

2-Fluoro-5-nitrophenyl alcohol

2-Fluoro-5-nitronbenzyl alcohol

2-Fluoro-5-nitrobenzyl alcohol 96%

2-Fluoro-5-nitrobenzenemethanol

2-Fluoro-5-nitrobenzyl alcohol 95+%

Benzenemethanol, 2-fluoro-5-nitro-

63878-73-9

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