Thioflavin T
- Product Name
- Thioflavin T
- CAS No.
- 2390-54-7
- Chemical Name
- Thioflavin T
- Synonyms
- THIOFLAVIN T;ThiofL;avin T;CI 49005;CI NO 49005;hioflavineT;Setoflavin T;SETOFLAVINE T;THIOFLAVINE T;BASIC YELLOW 1
- CBNumber
- CB6676791
- Molecular Formula
- C17H19ClN2S
- Formula Weight
- 318.86
- MOL File
- 2390-54-7.mol
Thioflavin T Property
- Melting point:
- 211-212 °C (decomp)
- Density
- 1.301g/cm3 at 20℃
- vapor pressure
- 0Pa at 25℃
- storage temp.
- Store below +30°C.
- solubility
- methanol: soluble1mg/mL
- Colour Index
- 49005
- form
- Powder
- color
- Yellow to ochre-yellow
- BRN
- 3922452
- InChI
- InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
- InChIKey
- JADVWWSKYZXRGX-UHFFFAOYSA-M
- SMILES
- C1(=[N+](C)C2C=CC(C)=CC=2S1)C1C=CC(N(C)C)=CC=1.[Cl-]
- LogP
- 3.02 at 25℃ and pH7.98
- CAS DataBase Reference
- 2390-54-7(CAS DataBase Reference)
- EPA Substance Registry System
- Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7)
Safety
- Safety Statements
- 24/25
- RIDADR
- 2811
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 32041300
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T3516
- Product name
- Thioflavin T
- Purity
- used as stain for amyloid
- Packaging
- 5g
- Price
- $36.6
- Updated
- 2024/03/01
- Product number
- 8.40072
- Product name
- Thioflavine T (C.I.No.49005)
- Purity
- ≥73% sulfur basis
- Packaging
- 5G
- Price
- $102
- Updated
- 2024/03/01
- Product number
- 596200
- Product name
- Thioflavin T
- Packaging
- 500mg
- Price
- $123
- Updated
- 2024/03/01
- Product number
- T0558
- Product name
- Basic Yellow 1
- Packaging
- 25g
- Price
- $73
- Updated
- 2024/03/01
- Product number
- J61043
- Product name
- Thioflavine T, tech. 75%
- Packaging
- 5g
- Price
- $21.65
- Updated
- 2024/03/01
Thioflavin T Chemical Properties,Usage,Production
Chemical Properties
yellow to ochre-yellow powder
Uses
Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.
Uses
A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease
Definition
ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.
Preparation
4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.
General Description
Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.
Biochem/physiol Actions
Cell permeable: yes
storage
Store at -20°C
Properties and Applications
colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.
| Standard( Silk ) | Light Fastness | Persperation Fastness | Ironing Fastness | Soaping | |||
| Fading | Stain | Fading | Stain | Fading | Stain | ||
| C | 3 | 2-3 | 4 | 1 | |||
Purification Methods
Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]
Thioflavin T Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Thioflavin T manufacturers
- Product
- THIOFLAVIN T 2390-54-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20tons
- Release date
- 2024-09-23
- Product
- Thioflavine T 2390-54-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-20
- Product
- Thioflavine T 2390-54-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-06-21