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Thioflavine T

Product Name
Thioflavine T
CAS No.
2390-54-7
Chemical Name
Thioflavine T
Synonyms
THIOFLAVIN T;ThiofL;avin T;CI 49005;CI NO 49005;hioflavineT;Setoflavin T;SETOFLAVINE T;THIOFLAVINE T;BASIC YELLOW 1
CBNumber
CB6676791
Molecular Formula
C17H19ClN2S
Formula Weight
318.86
MOL File
2390-54-7.mol
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Thioflavine T Property

Melting point:
211-212 °C (decomp)
Density 
1.301g/cm3 at 20℃
vapor pressure 
0Pa at 25℃
storage temp. 
Store below +30°C.
solubility 
methanol: soluble1mg/mL
Colour Index 
49005
form 
Powder
color 
Yellow to ochre-yellow
BRN 
3922452
LogP
3.02 at 25℃ and pH7.98
CAS DataBase Reference
2390-54-7(CAS DataBase Reference)
EPA Substance Registry System
Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7)
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Safety

Safety Statements 
24/25
RIDADR 
2811
WGK Germany 
3
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
32041300
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3516
Product name
Thioflavin T
Purity
used as stain for amyloid
Packaging
5g
Price
$36.6
Updated
2024/03/01
Sigma-Aldrich
Product number
8.40072
Product name
Thioflavine T (C.I.No.49005)
Purity
≥73% sulfur basis
Packaging
5G
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
596200
Product name
Thioflavin T
Packaging
500mg
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
T0558
Product name
Basic Yellow 1
Packaging
25g
Price
$73
Updated
2024/03/01
Alfa Aesar
Product number
J61043
Product name
Thioflavine T, tech. 75%
Packaging
5g
Price
$21.65
Updated
2024/03/01
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Thioflavine T Chemical Properties,Usage,Production

Chemical Properties

yellow to ochre-yellow powder

Uses

Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.

Uses

A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease

Definition

ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.

Preparation

4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.

General Description

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at -20°C

Properties and Applications

colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.

Standard( Silk ) Light Fastness Persperation Fastness Ironing Fastness Soaping
Fading Stain Fading Stain Fading Stain
C 3 2-3 4 1

Purification Methods

Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]

Thioflavine T Preparation Products And Raw materials

Raw materials

Preparation Products

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Thioflavine T Suppliers

Hubei Shinader new materials Co., Ltd.
Tel
08615271879636; 15271879636
Email
shinader@163.com
Country
China
ProdList
34
Advantage
58
Tangshan Moneide Trading Co., Ltd.
Tel
0315-8309571 15633399667
Fax
+86-315-7726572
Email
sales@moneidechem.com
Country
China
ProdList
703
Advantage
57
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13913916777;
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17840
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18736
Advantage
57
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View Lastest Price from Thioflavine T manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
Thioflavine T 2390-54-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-21
Hebei Guanlang Biotechnology Co., Ltd.
Product
Thioflavine T 2390-54-7
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-07-07
Career Henan Chemical Co
Product
Thioflavine T 2390-54-7
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-20

2390-54-7, Thioflavine TRelated Search:


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