Thioflavin T

Product Name: Thioflavin T
CAS No.: 2390-54-7
Chemical Name: Thioflavin T
Synonyms: THIOFLAVIN T;ThiofL;avin T;CI 49005;CI NO 49005;hioflavineT;Setoflavin T;SETOFLAVINE T;THIOFLAVINE T;BASIC YELLOW 1
CBNumber: CB6676791
Molecular Formula: C17H19ClN2S
Formula Weight: 318.86
MOL File: 2390-54-7.mol

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Thioflavin T Property

Melting point:: 211-212 °C (decomp)
Density: 1.301g/cm3 at 20℃
vapor pressure: 0Pa at 25℃
storage temp.: Store below +30°C.
solubility: methanol: soluble1mg/mL
Colour Index: 49005
form: Powder
color: Yellow to ochre-yellow
BRN: 3922452
InChI: InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChIKey: JADVWWSKYZXRGX-UHFFFAOYSA-M
SMILES: C1(=[N+](C)C2C=CC(C)=CC=2S1)C1C=CC(N(C)C)=CC=1.[Cl-]
LogP: 3.02 at 25℃ and pH7.98
CAS DataBase Reference: 2390-54-7(CAS DataBase Reference)
EPA Substance Registry System: Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7)

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Safety

Safety Statements: 24/25
RIDADR: 2811
WGK Germany: 3
TSCA: Yes
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 32041300

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T3516
Product name: Thioflavin T
Purity: used as stain for amyloid
Packaging: 5g
Price: $36.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.40072
Product name: Thioflavine T (C.I.No.49005)
Purity: ≥73% sulfur basis
Packaging: 5G
Price: $102
Updated: 2024/03/01

Sigma-Aldrich

Product number: 596200
Product name: Thioflavin T
Packaging: 500mg
Price: $123
Updated: 2024/03/01

TCI Chemical

Product number: T0558
Product name: Basic Yellow 1
Packaging: 25g
Price: $73
Updated: 2024/03/01

Alfa Aesar

Product number: J61043
Product name: Thioflavine T, tech. 75%
Packaging: 5g
Price: $21.65
Updated: 2024/03/01

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Thioflavin T Chemical Properties,Usage,Production

Chemical Properties

yellow to ochre-yellow powder

Uses

Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.

Uses

A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease

Definition

ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.

Preparation

4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.

General Description

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at -20°C

Properties and Applications

colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.

Standard( Silk )	Light Fastness	Persperation Fastness		Ironing Fastness		Soaping
Standard( Silk )	Light Fastness	Fading	Stain	Fading	Stain	Fading	Stain
C	3	2-3		4		1

Purification Methods

Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]

Thioflavin T Preparation Products And Raw materials

Raw materials

Preparation Products

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Thioflavin T Suppliers

Belgium 2 China 183 Europe 2 Germany 7 India 21 Japan 7 Poland 2 South Korea 1 Spain 1 Switzerland 2 United Kingdom 8 United States 47 USA 1 Global 284

Avonchem/Chromos Express Ltd.

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Discovery Fine Chemicals Ltd.

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NBS Biologicals

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Fisher Scientific Uk Ltd.

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Biosynth Carbosynth

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Leancare Ltd.

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CARBONE SCIENTIFIC CO.,LTD

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VWR International

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View Lastest Price from Thioflavin T manufacturers

Hubei Lidu New Material Technology Co., Ltd

Product: THIOFLAVIN T 2390-54-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-09-23

Hebei Weibang Biotechnology Co., Ltd

Product: Thioflavine T 2390-54-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-20

Hebei Mojin Biotechnology Co., Ltd

Product: Thioflavine T 2390-54-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-06-21

2390-54-7, Thioflavin TRelated Search:

Basic Violet 1 Curcumin N,N-Dimethylformamide 2,2'-Dithiobis(benzothiazole) Ammonium chloride Benzothiazole 28 BASIC YELLOW 28 Choline chloride 2-Mercaptobenzothiazole 3-Dimethylaminopropylamine Alkaline Phosphatase Sodium chloride Potassium chloride Theaflavin Riboflavin N,N-Dimethylacetamide PHENYL VALERATE Phosphorus

2-[4-(dimethylamino)phenyl]-3,6-dimethyl-benzothiazoliuchloride

Benzothiazolium,2-[4-(dimethylamino)phenyl]-3,6-dimethyl-,chloride

Thioflavine T (C.I.No.49005) for synthesis

Thioflavin T (Absorbance(E1%1cm) >=750 (410 nm to 414 nm, H2O)

Thioflavin T *CAS 2390-54-7*

avin T

ThiofL

LABOTEST-BB LT00451909

BASIC YELLOW 1

CI 49005

CI NO 49005

SETOFLAVINE T

THIOFLAVINE T

THIOFLAVINE TG

THIOFLAVINE T, TCN, TG

THIOFLAVIN T

2-[4-(dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride

THIOFLAVINET,TG

Basic yellow 1 (C.I. 49005)

THIOFLAVINE T, FOR MICROSCOPY

ThioflavineTC.I.49005

C.I. Basic Yellow 1

Basic Yellow1, Thioflavine T

4-(3,6-Dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline chloride

Setoflavin T

Thioflavine TCN

Thioflavin T 25GR

Thioflavin T 5GR

Setoflavine T Thioflavine T

Acronol Yellow T

2-(4-(DiMethylaMino)phenyl)-3,6-diMethylbenzo[d]thiazol-3-iuM chloride

ThioflavinT,Basic Yellow1, Thioflavine T

Thioflavin T - CAS 2390-54-7 - Calbiochem

Thioflavine T (C.I.No.49005)

Benzothiazolium,2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (1:1)

Thioflavine T (C.I.No.405)

THIOFLAVINE T (C.I.NO.49005) FOR SYNTHES

hioflavineT

C.I.Basic Yellow 1:C.I.49005

thioflavin T (c.i. 49005)

2-[4-(dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chlo...

TIANFUCHEM-- 2390-54-7--High purity Thioflavine T in stock

Thioflavin T for microscopy (C.I. No. 49005), 90%

THIOFLAVINE T Extra Pure

2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride

Crocein Orange G/Gardenia yellow pigment

Thioflavin T, Fluorescent cell-permeable amyloid binding benzothiazole salt

2390-54-7

C17H19ClN2S

C17H19N2SCl

C17H19CN2S

Detection

Fluorescent Probes, Labels, Particles and Stains

Biochemicals and Reagents

BioChemical

Biochemistry

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Vitamins