ChemicalBook > CAS DataBase List > Thioflavin T

Thioflavin T

Product Name
Thioflavin T
CAS No.
2390-54-7
Chemical Name
Thioflavin T
Synonyms
THIOFLAVIN T;ThiofL;avin T;CI 49005;CI NO 49005;hioflavineT;Setoflavin T;SETOFLAVINE T;THIOFLAVINE T;BASIC YELLOW 1
CBNumber
CB6676791
Molecular Formula
C17H19ClN2S
Formula Weight
318.86
MOL File
2390-54-7.mol
More
Less

Thioflavin T Property

Melting point:
211-212 °C (decomp)
Density 
1.301g/cm3 at 20℃
vapor pressure 
0Pa at 25℃
storage temp. 
Store below +30°C.
solubility 
methanol: soluble1mg/mL
Colour Index 
49005
form 
Powder
color 
Yellow to ochre-yellow
BRN 
3922452
InChI
InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChIKey
JADVWWSKYZXRGX-UHFFFAOYSA-M
SMILES
C1(=[N+](C)C2C=CC(C)=CC=2S1)C1C=CC(N(C)C)=CC=1.[Cl-]
LogP
3.02 at 25℃ and pH7.98
CAS DataBase Reference
2390-54-7(CAS DataBase Reference)
EPA Substance Registry System
Benzothiazolium, 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (2390-54-7)
More
Less

Safety

Safety Statements 
24/25
RIDADR 
2811
WGK Germany 
3
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
32041300
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T3516
Product name
Thioflavin T
Purity
used as stain for amyloid
Packaging
5g
Price
$36.6
Updated
2024/03/01
Sigma-Aldrich
Product number
8.40072
Product name
Thioflavine T (C.I.No.49005)
Purity
≥73% sulfur basis
Packaging
5G
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
596200
Product name
Thioflavin T
Packaging
500mg
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
T0558
Product name
Basic Yellow 1
Packaging
25g
Price
$73
Updated
2024/03/01
Alfa Aesar
Product number
J61043
Product name
Thioflavine T, tech. 75%
Packaging
5g
Price
$21.65
Updated
2024/03/01
More
Less

Thioflavin T Chemical Properties,Usage,Production

Chemical Properties

yellow to ochre-yellow powder

Uses

Textile dyeing, fluorescent sign paints, in combination with green or blue pigments to produce brilliant greens, phosphotungstic pigments.

Uses

A dye used to visualize beta-amyloid plaques, like those associated with Alzheimer's Disease

Definition

ChEBI: Thioflavine T is an organic chloride salt having 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium as the counterion. It is widely used to visualise and quantify the presence of amyloids, both in vitro and in vivo. It has a role as a fluorochrome, a histological dye and a geroprotector. It contains a thioflavin T cation.

Preparation

4-(6-Methyl-2,3-dihydrobenzo[d]thiazol-2-yl)benzenamine?with methanol and hydrochloric acid or sulfuric acid, at 160 ~ 170 ℃ methylation under pressure.

General Description

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Biochem/physiol Actions

Cell permeable: yes

storage

Store at -20°C

Properties and Applications

colourful green light yellow. Soluble in cold water, soluble in hot water for yellow, easily soluble in ethanol and yellow, with green fluorescent. The strong sulfuric acid to colorless, a green fluorescent, diluted into light yellow.

Standard( Silk ) Light Fastness Persperation Fastness Ironing Fastness Soaping
Fading Stain Fading Stain Fading Stain
C 3 2-3 4 1

Purification Methods

Crystallise the chloride from *benzene/EtOH (1:1). [Beilstein 27 III/IV 5052.]

Thioflavin T Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Thioflavin T Suppliers

Belgium 2 China 186 Europe 2 Germany 7 India 21 Japan 7 Poland 2 South Korea 1 Spain 1 Switzerland 2 United Kingdom 8 United States 47 USA 1 Global 287
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Bio Connect Life Sciences
Tel
Email
info@bio-connect.nl
Country
United States
ProdList
261
Advantage
58
NILE CHEMICALS
Tel
--
Fax
--
Email
nilechem@vsnl.net
Country
United States
ProdList
1369
Advantage
61
Abcam
Tel
--
Fax
--
Email
us.orders@abcam.com
Country
United States
ProdList
6001
Advantage
50
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
Chem-Impex International, Inc. (CII)
Tel
--
Fax
--
Email
Customer@chemimpex.com
Country
United States
ProdList
893
Advantage
58
Glentham Life Sciences Ltd
Tel
--
Fax
--
Email
info@glentham.com
Country
United States
ProdList
2026
Advantage
58
Glixx Laboratories Inc.
Tel
--
Fax
--
Email
sales@glixxlabs.com
Country
United States
ProdList
30
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
Voigt Global Distribution Inc
Tel
--
Fax
--
Email
Sales@Vgdusa.Com
Country
United States
ProdList
110
Advantage
58
MP Biomedicals, LLC. (Division of Valiant FC Co., Ltd.)
Tel
--
Fax
--
Email
serv@mpbio.com
Country
United States
ProdList
1854
Advantage
58
TCI America, Inc. (part of Tokyo Chemical Industry)
Tel
--
Fax
--
Email
Angelina.Crew@tcichemicals.com
Country
United States
ProdList
2053
Advantage
58
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Accela ChemBio Inc.
Tel
--
Fax
--
Email
info@accelachem.com
Country
United States
ProdList
1054
Advantage
50
Charkit Chemical Corporation
Tel
--
Fax
--
Email
sales@charkit.com
Country
United States
ProdList
2993
Advantage
65
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
AAT Bioquest, Inc.
Tel
--
Fax
--
Email
jack@aatbio.com
Country
United States
ProdList
169
Advantage
50
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Dudley Chemical Corp.
Tel
--
Fax
--
Email
dudley@dudley-chem.com
Country
United States
ProdList
687
Advantage
64
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
City Chemical LLC
Tel
--
Fax
--
Email
sales@citychemical.com
Country
United States
ProdList
6708
Advantage
72
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
AnaSpec, Inc.
Tel
--
Fax
--
Email
service@anaspec.com
Country
United States
ProdList
4871
Advantage
77
Pylam Products Company, Inc.
Tel
--
Fax
--
Email
sales@pylamdyes.com
Country
United States
ProdList
3257
Advantage
30
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
RAL Diagnostic Stains and Reagents Corporation
Tel
--
Fax
--
Email
biostains@yahoo.com
Country
United States
ProdList
79
Advantage
30
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
EMD Biosciences, Inc.
Tel
--
Fax
--
Email
technical@calbiochem.com
Country
United States
ProdList
6529
Advantage
66
Aakash Chemicals and Dye-Stuffs, Inc.
Tel
--
Fax
--
Email
info@aakashchemicals.com
Country
United States
ProdList
1012
Advantage
54
More
Less

View Lastest Price from Thioflavin T manufacturers

Hubei Lidu New Material Technology Co., Ltd
Product
THIOFLAVIN T 2390-54-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-09-23
Hebei Weibang Biotechnology Co., Ltd
Product
Thioflavine T 2390-54-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-20
Hebei Mujin Biotechnology Co.,Ltd
Product
Thioflavine T 2390-54-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-21

2390-54-7, Thioflavin TRelated Search:

Basic Violet 1 Curcumin N,N-Dimethylformamide 2,2'-Dithiobis(benzothiazole) Ammonium chloride Benzothiazole 28 BASIC YELLOW 28 Choline chloride 2-Mercaptobenzothiazole 3-Dimethylaminopropylamine Alkaline Phosphatase Sodium chloride Potassium chloride Theaflavin Riboflavin N,N-Dimethylacetamide PHENYL VALERATE Phosphorus

  • 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-benzothiazoliuchloride
  • Benzothiazolium,2-[4-(dimethylamino)phenyl]-3,6-dimethyl-,chloride
  • Thioflavine T (C.I.No.49005) for synthesis
  • Thioflavin T (Absorbance(E1%1cm) >=750 (410 nm to 414 nm, H2O)
  • Thioflavin T *CAS 2390-54-7*
  • avin T
  • ThiofL
  • LABOTEST-BB LT00451909
  • BASIC YELLOW 1
  • CI 49005
  • CI NO 49005
  • SETOFLAVINE T
  • THIOFLAVINE T
  • THIOFLAVINE TG
  • THIOFLAVINE T, TCN, TG
  • THIOFLAVIN T
  • 2-[4-(dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride
  • THIOFLAVINET,TG
  • Basic yellow 1 (C.I. 49005)
  • THIOFLAVINE T, FOR MICROSCOPY
  • ThioflavineTC.I.49005
  • C.I. Basic Yellow 1
  • Basic Yellow1, Thioflavine T
  • 4-(3,6-Dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline chloride
  • Setoflavin T
  • Thioflavine TCN
  • Thioflavin T 25GR
  • Thioflavin T 5GR
  • Setoflavine T Thioflavine T
  • Acronol Yellow T
  • 2-(4-(DiMethylaMino)phenyl)-3,6-diMethylbenzo[d]thiazol-3-iuM chloride
  • ThioflavinT,Basic Yellow1, Thioflavine T
  • Thioflavin T - CAS 2390-54-7 - Calbiochem
  • Thioflavine T (C.I.No.49005)
  • Benzothiazolium,2-[4-(dimethylamino)phenyl]-3,6-dimethyl-, chloride (1:1)
  • Thioflavine T (C.I.No.405)
  • THIOFLAVINE T (C.I.NO.49005) FOR SYNTHES
  • hioflavineT
  • C.I.Basic Yellow 1:C.I.49005
  • thioflavin T (c.i. 49005)
  • 2-[4-(dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chlo...
  • TIANFUCHEM-- 2390-54-7--High purity Thioflavine T in stock
  • Thioflavin T for microscopy (C.I. No. 49005), 90%
  • THIOFLAVINE T Extra Pure
  • 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride
  • Crocein Orange G/Gardenia yellow pigment
  • Thioflavin T, Fluorescent cell-permeable amyloid binding benzothiazole salt
  • 2390-54-7
  • C17H19ClN2S
  • C17H19N2SCl
  • C17H19CN2S
  • Detection
  • Fluorescent Probes, Labels, Particles and Stains
  • Biochemicals and Reagents
  • BioChemical
  • Biochemistry
  • Vitamin Derivatives
  • Vitamins