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Cefcapene

Product Name
Cefcapene
CAS No.
135889-00-8
Chemical Name
Cefcapene
Synonyms
CEFCAPENE;s1006;Cefcamate;Cefcapine;Cefcapinaxil;Cefcarpinic Acid;CEFCAPENE Impurity;Cefcapene Impurity 5;Cefcapene Impurity 7;Cefcapene pivoxil free acid
CBNumber
CB6680909
Molecular Formula
C17H19N5O6S2
Formula Weight
453.49
MOL File
135889-00-8.mol
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Cefcapene Property

Boiling point:
936.0±65.0 °C(Predicted)
Density 
1.63
pka
2.58±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C242545
Product name
Cefcapene
Packaging
25mg
Price
$4125
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007951
Product name
CEFCAPENE
Purity
95.00%
Packaging
25MG
Price
$4908.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007951
Product name
CEFCAPENE
Purity
95.00%
Packaging
1MG
Price
$925.05
Updated
2021/12/16
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Cefcapene Chemical Properties,Usage,Production

Uses

Cefcapene is a metabolite of Cefcapene Pivoxil (C242550). Antibacterial, orally absorbed cephalosporin that is used in the treatment of bacterial infections.

Definition

ChEBI: Cefcapene is a cephalosporin compound having (carbamoyloxy)methyl and N-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino side-groups. It is used (generally as the corresponnding pivaloyloxymethyl ester prodrug) as an oral antibacterial. It has a role as an antibacterial drug. It is a cephalosporin, a carboxylic acid, a carbamate ester, an enamide, a member of 1,3-thiazoles and a secondary carboxamide.

Antimicrobial activity

A semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefcapene pivoxil. Activity and uses are similar to those of cefditoren.
Available in Japan.

Pharmacokinetics

Cefcapene is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcapene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
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Cefcapene Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefcapene Suppliers

BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
American Custom Chemicals Corporation
Tel
--
Fax
--
Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
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View Lastest Price from Cefcapene manufacturers

Guangzhou Tosun Pharmaceutical Ltd
Product
Cefcapene Impurity 7 135889-00-8
Price
US $0.00-0.00/mg
Min. Order
5mg
Purity
95%+
Supply Ability
1000
Release date
2024-12-18
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Cefcapene 135889-00-8
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-25
Career Henan Chemical Co
Product
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 135889-00-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-09-04

135889-00-8, CefcapeneRelated Search:


  • CEFCAPENE
  • s1006
  • (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-pentenoylamino]-8-oxo-3-(carbamoyloxymethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (7R)-7-[[(Z)-2-(2-Amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-3-[(carbamoyloxy)methyl]cepham-3-ene-4-carboxylic acid
  • Cefcamate
  • Cefcapene pivoxil free acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(6R,7R)-
  • (6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
  • (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic
  • Cefcapene Impurity 5
  • Cefcapene Pivoxil Impurity 1
  • Cefcapene Pivoxil Impurity 4 (Cefcapene)
  • Cefcapene Impurity 7
  • (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicaci
  • Cefcarpinic Acid
  • Cefcapene Pivoxil Hydrolized Impurity 1
  • Cefcapene pivoxil Impurity 16
  • Cefcapene pivoxil Impurity 10
  • Cefcapinaxil
  • CEFCAPENE Impurity
  • Cefcapine
  • 135889-00-8
  • C23H29N5O8S2
  • C17H19N5O6S2
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds