ChemicalBook > CAS DataBase List > DSPACER CEP

DSPACER CEP

Product Name: DSPACER CEP
CAS No.: 129821-76-7
Chemical Name: DSPACER CEP
Synonyms: dSPACER;DSPACER CEP;dSpacer Amidite;dSpacer CE Phosphoramidite;2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoraMidite;1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite;1,2-Dideoxy-5'-O-DMT-D-ribose 3'-CE phosphoramidite;5'-O-(4,4'-dimethoxytrityl)-1,2-dideoxyribose-3-CE-Phosphoramidite;2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite(dSpacer CE Phosphoramidite);5'-O-Dimethoxytrityl-1',2'-Dideoxyribose-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
CBNumber: CB6682433
Molecular Formula: C35H45N2O6P
Formula Weight: 620.72
MOL File: 129821-76-7.mol

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DSPACER CEP Property

Boiling point:: 658.6±55.0 °C(Predicted)
pka: 3.45±0.70(Predicted)
form: Oil
Appearance: white, off white to faint yellow oil
InChIKey: XZGSDLJMHWJDHL-DQCWULFNNA-N
SMILES: P(OCCC#N)(N(C(C)C)C(C)C)O[C@H]1CCO[C@@H]1COC(C1C=CC=CC=1)(C1=CC=C(C=C1)OC)C1C=CC(=CC=1)OC |&1:14,18,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: PD08984
Product name: 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite
Packaging: 50mg
Price: $184
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD08984
Product name: 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite
Packaging: 100mg
Price: $315
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD08984
Product name: 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite
Packaging: 250mg
Price: $525
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD08984
Product name: 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite
Packaging: 500mg
Price: $600
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD08984
Product name: 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite
Packaging: 1g
Price: $850
Updated: 2021/12/16

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DSPACER CEP Chemical Properties,Usage,Production

Description

A compound for the phosphoramidite synthesis of oligonucleotides and the creation of the abasic step in the oligonucleotide sequence.

Cleavage of the N-glycosyl bond between a base and its 2-deoxyribose moiety in DNA generates an apurinic/apyrimidinic (so-called abasic) site. This phenomenon, which is referred to as depurination or depyrimidination occurs spontaneously under physiological conditions.

Abasic phosphoramidites are used in DNA and oligonucleotide synthesis. Abasic phosphoramidite imitates the loss of base pairing ability by a nucleotide. This modification of phosphoramidite is more stable than the natural abasic insert and can be used when examining DNA damage and repair.

Abasic phosphoramidite (dSpacer CE-Phosphoramidite) is a modification of 1′,2′-dideoxyribose, contains a DMT protection of the hydroxymethyl group, and exhibits stability during synthesis and purification of oligonucleotides under standard conditions using AMA mixture, ammonium hydroxide / 40% methylamine (1:1).

Uses

dSPACER is a compound for the phosphoramidite synthesis of oligonucleotides and the creation of the abasic step in the oligonucleotide sequence.Abasic phosphoramidites are used in DNA and oligonucleotide synthesis.

DSPACER CEP Preparation Products And Raw materials

Raw materials

Preparation Products

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129821-76-7, DSPACER CEPRelated Search:

DMT-2'O-Methyl-rU Phosphoramidite DMT-dC(bz) Phosphoramidite DMT-dG(ib) Phosphoramidite DMT-dA(bz) Phosphoramidite DMT-dT Phosphoramidite DMT-2′O-TBDMS-rU Phosphoramidite 5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE DMT-2'O-TBDMS-rA(bz) Phosphoramidite 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-PHENOXYACETYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE N-blocked-5'-O-DMT-2'-O-TBDMS CED cytidine phosphoramidite N-blocked-5'-O-DMT 3'-CED iododeoxyuridine phosphoramidite 5-BROMO-DC CEP 5'-O-(4,4'-DIMETHOXYTRITYL)-DEOXYINOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5'-DIMETHOXYTRITYL-N2-PHENOXYACETYL-2'-DEOXYGUANOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5'-DMT-5-BROMO-DU PHOSPHORAMIDITE (CHIRAL) 5'-O-(4,4'-DIMETHOXYTRITYL)-5-FLUORODEOXYURIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE DMT-DCYTIDINE (N6-BENZOYL) CYANOETHYL PHOSPHORAMIDITE) 2'-DEOXYNEBULARINE CEP

DSPACER CEP

1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite

2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoraMidite

dSPACER

1,4-Anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-D-erythro-pentitol 2-cyanoethyl bis(1-methylethyl)phosphoramidite

1,2-Dideoxy-5'-O-DMT-D-ribose 3'-CE phosphoramidite

D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

D-erythro-Pentitol,1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 2-cyanoethylbis(1-methylethyl)phosphoramidite (9CI)

5'-O-Dimethoxytrityl-1',2'-Dideoxyribose-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

(2R,3S)-2-((bis(4-methoxy phenyl)(phenyl)methoxy)methyl)-tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite

5'-O-(4,4'-dimethoxytrityl)-1,2-dideoxyribose-3-CE-Phosphoramidite

dSpacer CE Phosphoramidite

dSpacer Amidite

2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite(dSpacer CE Phosphoramidite)

129821-76-7

C35H45N2O6P

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