L-Norleucine

Product Name: L-Norleucine
CAS No.: 327-57-1
Chemical Name: L-Norleucine
Synonyms: Nle;G123;Caprine;L-Nle-OH;H-NLE-OH;H-L-NLE-OH;NORLEUCINE;H-AHX(2)-OH;L-NORLEUCINE;Glycoleucine
CBNumber: CB6684260
Molecular Formula: C6H13NO2
Formula Weight: 131.17
MOL File: 327-57-1.mol

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L-Norleucine Property

Melting point:: >300 °C (lit.)
alpha: 22 º (c=2, 6N HCl)
Density: 1.1720 (estimate)
refractive index: 23 ° (C=5, 5mol/L HCl)
Flash point:: 275 °C
storage temp.: Sealed in dry,Room Temperature
solubility: 1.6 g/100 mL (23°C)
Boiling point:: 234.0±23.0 °C(Predicted)
form: Crystalline Powder
pka: 2.335(at 25℃)
color: White to off-white
PH: 6.08
optical activity: +4.725 (H2O) +24.525 (5 mol dm-3 HCl)
Water Solubility: 1.6 g/100 mL (23 ºC)
Sublimation: 275 ºC
Merck: 14,6706
BRN: 1721750
Major Application: detection
InChI: 1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChIKey: LRQKBLKVPFOOQJ-YFKPBYRVSA-N
SMILES: CCCC[C@H](N)C(O)=O
LogP: 0.920 (est)
CAS DataBase Reference: 327-57-1(CAS DataBase Reference)
NIST Chemistry Reference: L-Norleucine(327-57-1)
EPA Substance Registry System: L-Norleucine (327-57-1)

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37-24/25-22
WGK Germany: 3
RTECS: RC6308000
TSCA: TSCA listed
HS Code: 29224995
Storage Class: 11 - Combustible Solids
Hazard Classifications: Skin Sens. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N6877
Product name: L-Norleucine
Purity: ≥98% (TLC)
Packaging: 1g
Price: $74.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: N6877
Product name: L-Norleucine
Purity: ≥98% (TLC)
Packaging: 5g
Price: $243
Updated: 2025/07/31

TCI Chemical

Product number: N0303
Product name: L-Norleucine
Purity: >99.0%(T)
Packaging: 100mg
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: N0303
Product name: L-Norleucine
Purity: >99.0%(T)
Packaging: 1g
Price: $42
Updated: 2024/03/01

Sigma-Aldrich

Product number: N8513
Product name: L-Norleucine
Purity: suitable for amino acid analysis, BioReagent
Packaging: 100mg
Price: $69.4
Updated: 2025/07/31

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L-Norleucine Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

A non-essential amino acid. Used as internal standard in amino acid analysis.

Uses

As a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.

Biochem/physiol Actions

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Purification Methods

Crystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]

L-Norleucine Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Norleucine Suppliers

Americas 1 Belgium 1 Canada 3 China 285 Europe 3 France 2 Germany 9 India 7 Japan 9 South Korea 1 Switzerland 5 The Netherlands 1 United Kingdom 9 United States 46 USA 1 Global 383

Taizhou Tianhong Biochemistry Technology Co., Ltd.

Tel: 0523-86132544 15366717810
Fax: 0523-86201489
Email: sales@thbiochem.com
Country: China
ProdList: 377
Advantage: 55

Hangzhou Xinshuo New Material Technology Co., Ltd.

Tel: 18257124775,15967699685 15967699685;
Email: 3762199508@qq.com
Country: China
ProdList: 35
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
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Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9411
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44802
Advantage: 61

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

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View Lastest Price from L-Norleucine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: H-Nle-OH 327-57-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1T+
Release date: 2023-09-24

Zhuozhou Wenxi import and Export Co., Ltd

Product: L-Norleucine 327-57-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Sichuan Jiaying Lai Technology Co.,LTD

Product: H-Nle-OH 327-57-1
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-25

327-57-1, L-NorleucineRelated Search:

H-ILE-NH2 HCL L-Isoleucine Nonivamide Copper Peptide N-EPSILON-ACETYL-L-LYSINE AC-LYS-OH BOC-LYS(TFA)-OH L(+)-Homoarginine hydrochloride Tripeptide-1 L-2-Aminoadipic acid 1-Amino-1-cyclohexanecarboxylic acid N6-Cbz-L-Lysine AC-LYS-OME HCL Fmoc-Lys(Boc)-OH N-ALPHA-TERT-BUTYLOXYCARBONYL-L-NORLEUCINE,N-BOC-L-NORLEUCINE,N-ALPHA-T-BUTYLOXYCARBONYL-L-NORLEUCINE,N-ALPHA-T-BUTOXYCARBONYL-L-NORLEUCINE N-BENZYLOXYCARBONYL-L-NORLEUCINE,N-CBZ-L-NORLEUCINE,N-CARBOBENZOXY-L-NORLEUCINE 6-[[(4-methylphenyl)sulphonyl]amino]hexanoic acid H-LYS(ME)-OH HCL

alpha-aminocaproic acid

L(+)-Norleucine, 99+% 1GR

Norleucine Solution

(S)-Norleucine

Norleucine, L- (8CI)

Glycoleucine

Hexanoic acid, 2-amino-, (S)-

n-C4H9CH(NH2)COOH

L-(+)-NORLEUCINE

L-NORLEUCINE

L-ALPHA-AMINOCAPROIC ACID

L-(+)-Norleucine, 98+%

Nle

L-NorLeucine, 98.5%

L-Nle-OH

L-NORLEUCINE BIOREAGENT, SUITA&

H-Nle-OH (S)-(+)-2-Aminohexanoic acid (S)-2-Aminocaproic acid L(+)-Norleucine L-2-Aminohexanoic acid

Caprine

L-ALPHA-AMINO-N-CAPROIC ACID

H-L-NHCH[CH3(CH2)3]-COOH

H-L-NLE-OH

H-L-NORLEUCINE

H-L-2-AMINOCAPROIC ACID

H-NLE-OH

H-AHX(2)-OH

H-ACPO(2)-OH

L(+)-Norleucine, 99+%

H-NLE-OH, L-NORLEUCINE

NORLEUCINE, L-(AMINOCAPROIC ACID)(RG)

L-Norleucine, (S)-(+)-2-Aminohexanoicacid,(S)-2-Aminocaproicacid

L-Norleucine, (S)-2-Aminohexanoic acid

(S)-(+)-2-Aminohexanoic acid (S)-2-Aminocaproic acid

(2S)-2-Aminohexanoic acid

2-Aminohexanoic acid, (L)

(S)-2-AMINOCAPROIC ACID

(S)-(+)-2-AMINOHEXANOIC ACID

RARECHEM EM WB 0162

NORLEUCINE, L-

NORLEUCINE

N-NORLEUCINE

L-2-AMINOHEXANOIC ACID

L-2-AMINO-CAPROIC ACID

L-A-AMINO-N-CAPROIC ACID

L-NORLEUCINE AMINO ACID INTERNAL*STANDAR D

L-NORLEUCINE, 99+% (99% EE/GLC)

L-NORLEUCINE 99%MIN

(S)-(+)-2-Aminohexanoicacid~H-Nle-OH

L-2-Amino-n-caproic acid

2-ammoniohexanoate

L-Norleucine&gt

L-Norleucine USP/EP/BP

laevo-norleucine

G123

L-Norleucine,97%

NORLEUCINE, L-(AMINOCAPROIC ACID)

L-Norleucine, ≥ 99.0%

Metformin Impurity 46 Monomer

<sc>L</sc>-Norleucine