ChemicalBook > CAS DataBase List > L-Norleucine

L-Norleucine

Product Name
L-Norleucine
CAS No.
327-57-1
Chemical Name
L-Norleucine
Synonyms
Nle;G123;Caprine;L-Nle-OH;H-NLE-OH;H-L-NLE-OH;NORLEUCINE;H-AHX(2)-OH;L-NORLEUCINE;Glycoleucine
CBNumber
CB6684260
Molecular Formula
C6H13NO2
Formula Weight
131.17
MOL File
327-57-1.mol
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L-Norleucine Property

Melting point:
>300 °C (lit.)
alpha 
22 º (c=2, 6N HCl)
Density 
1.1720 (estimate)
refractive index 
23 ° (C=5, 5mol/L HCl)
Flash point:
275 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
1.6 g/100 mL (23°C)
Boiling point:
234.0±23.0 °C(Predicted)
form 
Crystalline Powder
pka
2.335(at 25℃)
color 
White to off-white
PH
6.08
optical activity
+4.725 (H2O) +24.525 (5 mol dm-3 HCl)
Water Solubility 
1.6 g/100 mL (23 ºC)
Sublimation 
275 ºC
Merck 
14,6706
BRN 
1721750
LogP
0.920 (est)
CAS DataBase Reference
327-57-1(CAS DataBase Reference)
NIST Chemistry Reference
L-Norleucine(327-57-1)
EPA Substance Registry System
L-Norleucine (327-57-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37-24/25-22
WGK Germany 
3
RTECS 
RC6308000
TSCA 
Yes
HS Code 
29224995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N6877
Product name
L-Norleucine
Purity
≥98% (TLC)
Packaging
1g
Price
$74.7
Updated
2025/07/31
Sigma-Aldrich
Product number
N6877
Product name
L-Norleucine
Purity
≥98% (TLC)
Packaging
5g
Price
$243
Updated
2025/07/31
TCI Chemical
Product number
N0303
Product name
L-Norleucine
Purity
>99.0%(T)
Packaging
100mg
Price
$16
Updated
2025/07/31
TCI Chemical
Product number
N0303
Product name
L-Norleucine
Purity
>99.0%(T)
Packaging
1g
Price
$42
Updated
2024/03/01
Sigma-Aldrich
Product number
N8513
Product name
L-Norleucine
Purity
suitable for amino acid analysis, BioReagent
Packaging
100mg
Price
$69.4
Updated
2025/07/31
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L-Norleucine Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

A non-essential amino acid. Used as internal standard in amino acid analysis.

Uses

As a non-essential amino acid, L-Norleucine can be used as internal standard in amino acid analysis.

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid comprising hexanoic acid carrying an amino group at C-2. It does not occur naturally.

Biochem/physiol Actions

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Purification Methods

Crystallise norleucine from water or aqueous MeOH. [Huffman & Ingersoll J Am Chem Soc 73 3366 1951, Beilstein 4 III 1386, 4 IV 2628.]

L-Norleucine Preparation Products And Raw materials

Raw materials

Preparation Products

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L-Norleucine Suppliers

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View Lastest Price from L-Norleucine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
H-Nle-OH 327-57-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1T+
Release date
2023-09-24
Zhuozhou Wenxi import and Export Co., Ltd
Product
L-Norleucine 327-57-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Sichuan Jiaying Lai Technology Co.,LTD
Product
H-Nle-OH 327-57-1
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-25

327-57-1, L-NorleucineRelated Search:

H-ILE-NH2 HCL L-Isoleucine Nonivamide Copper Peptide N-EPSILON-ACETYL-L-LYSINE AC-LYS-OH BOC-LYS(TFA)-OH L(+)-Homoarginine hydrochloride Tripeptide-1 L-2-Aminoadipic acid 1-Amino-1-cyclohexanecarboxylic acid N6-Cbz-L-Lysine AC-LYS-OME HCL Fmoc-Lys(Boc)-OH N-ALPHA-TERT-BUTYLOXYCARBONYL-L-NORLEUCINE,N-BOC-L-NORLEUCINE,N-ALPHA-T-BUTYLOXYCARBONYL-L-NORLEUCINE,N-ALPHA-T-BUTOXYCARBONYL-L-NORLEUCINE N-BENZYLOXYCARBONYL-L-NORLEUCINE,N-CBZ-L-NORLEUCINE,N-CARBOBENZOXY-L-NORLEUCINE 6-[[(4-methylphenyl)sulphonyl]amino]hexanoic acid H-LYS(ME)-OH HCL

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  • L-Norleucine, (S)-2-Aminohexanoic acid
  • (S)-(+)-2-Aminohexanoic acid (S)-2-Aminocaproic acid
  • (2S)-2-Aminohexanoic acid
  • 2-Aminohexanoic acid, (L)
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  • (S)-(+)-2-AMINOHEXANOIC ACID
  • RARECHEM EM WB 0162
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