8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE

Product Name: 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE
CAS No.: 51116-01-9
Chemical Name: 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE
Synonyms: BR-CGMP, NA;8-BR-CGMP NA;8-BROMO-CGMP NA;Einecs 256-993-8;8-BROMO-CGMP SODIUM;8-BR-CGMP SODIUM SALT;(115974-70-4) 8-AET-cGMP;8-BROMO-CGMP, SODIUM SALT;8-bromo-Cyclic GMP (sodium salt);8 Bromo cGMP sodium,8BromocGMP sodium
CBNumber: CB6687726
Molecular Formula: C10H12BrN5NaO7P
Formula Weight: 448.1
MOL File: 51116-01-9.mol

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8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Property

storage temp.: -20°C
solubility: H₂O: 100 mg/mL
form: powder
color: White to off-white
Water Solubility: Soluble to 100 mM in water

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Safety

WGK Germany: 3
F: 10-21
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B1381
Product name: 8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt
Purity: ≥98% (HPLC), powder
Packaging: 10mg
Price: $89.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 203820
Product name: Guanosine 3?,5?-cyclic Monophosphate, 8-Bromo-, Sodium Salt
Packaging: 25mg
Price: $166
Updated: 2024/03/01

Cayman Chemical

Product number: 15992
Product name: 8-bromo-Cyclic GMP (sodium salt)
Purity: ≥98%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 15992
Product name: 8-bromo-Cyclic GMP (sodium salt)
Purity: ≥98%
Packaging: 10mg
Price: $74
Updated: 2024/03/01

Sigma-Aldrich

Product number: B1381
Product name: 8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $179
Updated: 2024/03/01

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8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Chemical Properties,Usage,Production

Description

8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 μM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.

Chemical Properties

White powder

Uses

8-bromo-cGMP activates cGMP-dependent protein kinase. It can also inhibit acetylcholine-induced increases in intracellular calcium concentrations.

Definition

ChEBI: Sodium 8-bromo-3',5'-cyclic GMP is an organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a protein kinase G agonist and a muscle relaxant. It contains an 8-bromo-3',5'-cyclic GMP(1-).

Biological Activity

Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1 α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro .

storage

Desiccate at -20°C

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Suppliers

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51116-01-9, 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATERelated Search:

Guanosine 5'-monophosphate disodium salt Guanosine ADP 2-BROMO-4-METHYL-1H-IMIDAZOLE 2-BROMO-1-ETHOXYMETHYLIMIDAZOLE 8-BROMO-2'-DEOXYGUANOSINE GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT 8-Bromoguanosine 2-Bromo-1-methyl-1H-imidazole 2-BROMO-1,4-DIMETHYL-1H-IMIDAZOLE 8-BR-CGMP 8-BR-PET-CGMP SODIUM SALT INOSINE-3',5'-CYCLIC PHOSPHATE 8-BROMOGUANINE 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE 8-BROMOHYPOXANTHINE 2'-DCGMP SODIUM SALT 9-((2-hydroxy-1,3,2-dioxaphosphorinan-5-yl)oxymethyl)guanine P-oxide

8-bromoguanosine-3’,5’-cyclicmonophosphate(8-br-cgmp),sodiumsalt,

8-bromoguanosine 3:5-cyclic*monophosphate sodiu

8-Bromoguanosine-3,5-cyclomonophosphate sodium salt

Guanosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), monosodium salt

8-BROMOGUANOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM

8-BROMO-CGMP SODIUM SALT 8-BROMOGUANOSIN E-3',5

GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT

BR-CGMP, NA

8-BR-CGMP NA

8-BR-CGMP SODIUM SALT

8-BROMO-CGMP NA

8-BROMO-CGMP SODIUM

8-BROMO-CGMP, SODIUM SALT

8-BROMOGUANOSINE CYCLIC 3',5'-MONOPHOSPHATE SODIUM SALT

8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE

8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM

8-BROMOGUANOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT

8-BROMOGUANOSINE-3,5-CYCLICMONOPHOSPHATESODIUMSALT,ULTRAPURE

Einecs 256-993-8

(115974-70-4) 8-AET-cGMP

8-bromo-Cyclic GMP (sodium salt)

Guanosine 3,5-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 51116-01-9 - Calbiochem

8-Bromoguanosine3′,5′-cyclicmonophosphatesodiumsal

8 Bromo cGMP sodium,8BromocGMP sodium

51116-01-9

C10H10BrN5NaO7P

C10H10BrN5O7PNa

Cell Biology

Cell Signaling and Neuroscience

Biochemicals and Reagents

BioChemical

G Proteins and Cyclic Nucleotides

Cyclic Nucleotide Metabolism

Cyclic Nucleotides and Analogs

Nucleoside Analogs

Nucleosides, Nucleotides, Oligonucleotides

Cyclic Nucleotide related

Cyclic Nucleotide Metabolism

Cyclic Nucleotides and AnalogsSerine/Threonine Kinase Biology

G Proteins and Cyclic Nucleotides

Protein Kinase G (PKG)

Serine/Threonine Kinase Activators