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tert-Butyl carbamate

Product Name
tert-Butyl carbamate
CAS No.
4248-19-5
Chemical Name
tert-Butyl carbamate
Synonyms
BOC-NH2;T-BUTYL CARBAMATE;CARBAMIC ACID TERT-BUTYL ESTER;BOC-AMIDE;ert-Butyl carbamate;BOC Amide pure, 98%;TERT-BUTYL CARBAMATE;t-Butoxycarbonylamide;t tert-butyl carbamate;tert-Butyl carbaMate 5GR
CBNumber
CB6701653
Molecular Formula
C5H11NO2
Formula Weight
117.15
MOL File
4248-19-5.mol
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tert-Butyl carbamate Property

Melting point:
105-108 °C (lit.)
Boiling point:
218.95°C (rough estimate)
Density 
1.1274 (rough estimate)
refractive index 
1.4206 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
13.59±0.50(Predicted)
form 
Needles
color 
White to slightly yellow
Water Solubility 
Soluble in methylene chloride, chloroform, and alcohols. Slightly soluble in petroleum ether and water.
BRN 
1744500
CAS DataBase Reference
4248-19-5(CAS DataBase Reference)
NIST Chemistry Reference
Tert-butyl carbamate(4248-19-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
39-26-24/25
WGK Germany 
3
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
167398
Product name
tert-Butyl carbamate
Purity
98%
Packaging
5g
Price
$47.9
Updated
2024/03/01
Sigma-Aldrich
Product number
167398
Product name
tert-Butyl carbamate
Purity
98%
Packaging
1g
Price
$30.2
Updated
2023/01/07
TCI Chemical
Product number
B3132
Product name
tert-Butyl Carbamate
Purity
>98.0%(GC)
Packaging
5g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
B3132
Product name
tert-Butyl Carbamate
Purity
>98.0%(GC)
Packaging
25g
Price
$74
Updated
2024/03/01
Alfa Aesar
Product number
L00259
Product name
tert-Butyl carbamate, 98+%
Packaging
5g
Price
$45.65
Updated
2024/03/01
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tert-Butyl carbamate Chemical Properties,Usage,Production

Chemical Properties

White to slightly yellow needles

Uses

tert-Butyl carbamate was used in palladium-catalyzed synthesis of N-Boc-protected anilines. It was used in the synthesis of tetrasubstituted pyrroles, functionalized with ester or ketone groups at C-3 position.

Synthesis Reference(s)

The Journal of Organic Chemistry, 28, p. 3421, 1963 DOI: 10.1021/jo01047a033

General Description

Palladium-catalyzed cross-coupling reaction of tert-butyl carbamate with various aryl(Het) halides with Cs2CO3 as base in 1,4-dioxane (solvent) has been investigated.

tert-Butyl carbamate Preparation Products And Raw materials

Raw materials

Benzoyl peroxide N-Bromosuccinimide Di-tert-butyl dicarbonate PERCHLORIC ACID Trifluoroacetic acid tert-Butanol Chloroform Sodium cyanate Sodium hydroxide Allyl chloride Ammonia

Preparation Products

Docetaxel METHYL PENT-4-YN-2-YLCARBAMATE
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tert-Butyl carbamate Suppliers

Americas 1 Belgium 2 Canada 1 China 327 Europe 1 France 1 Germany 7 India 43 Japan 6 Russia 1 Switzerland 3 United Kingdom 11 United States 47 Global 451
Suzhou Highfine Biotech Co., Ltd
Tel
0512-69209928 18306209922
Fax
0512-68417696
Email
cathyjia@highfine.com
Country
China
ProdList
499
Advantage
75
Shanghai Hobor Chemical Co., Ltd
Tel
21-61026752 13918007836
Fax
021-51685238
Email
sales@hoborchem.com
Country
China
ProdList
346
Advantage
60
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Shanghai XinKai Chemical Technology Co., Ltd.
Tel
021-58930698 15921516558
Fax
86-021-58933679
Email
zhangyichao84@126.com
Country
China
ProdList
910
Advantage
55
Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375892 15562613975
Email
3416953599@qq.com
Country
China
ProdList
309
Advantage
58
New Energy Chemicals
Tel
0515-82159088 13770142076
Fax
86-0515-8215909
Email
twl@njuchem.com
Country
China
ProdList
213
Advantage
65
Shanghai Qiude Biochemical Engineering Co., Ltd
Tel
021-37285021 13472570865;
Fax
86-021-51714507
Email
info@pure-chiral.com
Country
China
ProdList
306
Advantage
64
Shanghai Tuolei Chemical Reagents Co., Ltd.
Tel
86-021-50318510
Fax
021-58650104
Country
China
ProdList
69
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
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View Lastest Price from tert-Butyl carbamate manufacturers

Anhui Dexinjia Biopharm Co., Ltd
Product
tert-Butyl carbamate 4248-19-5
Price
US $50.00-500.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5MT per month
Release date
2023-07-31
Hebei Weibang Biotechnology Co., Ltd
Product
tert-Butyl carbamate 4248-19-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-05
Hebei Yanxi Chemical Co., Ltd.
Product
tert-Butyl carbamate 4248-19-5
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-09-08

4248-19-5, tert-Butyl carbamateRelated Search:

Urethane tert-Butyl 4-aminobenzoate Rink Amide Linker tert-Butyl peroxybenzoate tert-Butyl glycinate Dibutyl phthalate tert-Butyl carbazate Chlorpropham RINK AMIDE RESIN Diethylene glycol monobutyl ether BUTYL OLEATE Butyl formate n-Butyl carbamate Butyl acetate tert-Butyl acetate POLYURETHANE Fomesafen 4-Aminobenzoic acid

  • tert-Butylcarbamate,98+%
  • tert-Butoxycarbonylamine
  • Carbamic Acid tert-Butyl EsterBoc-amide
  • tert-Butyl carbamate,Boc-amide
  • N-t-Butoxycarbonyl-amide(Boc-NH2)
  • ert-Butyl carbamate
  • Boc-NH2 N-t-Butoxycarbonyl-aMide
  • tert-Butyl carbaMate 5GR
  • tert-Butyl carbamate≥ 98%(GC)
  • CARBAMIC ACID TERT-BUTYL ESTER
  • BOC-NH2
  • BOC-AMIDE
  • tert-Butyl carbaMate 98%
  • tert-Butyl carbamate Synonyms BOC-amide
  • <i>tert</i>-Butyl carbamate
  • t tert-butyl carbamate
  • TERT-BUTYL CARBAMATE
  • T-BUTYL CARBAMATE
  • N-T-BUTOXYCARBONYL AMIDE
  • Carbamic acid, 1,1-dimethylethyl ester
  • methyl 3-((tert-butoxycarbonyl)amino)-3-(4-fluorophenyl)-2-hydroxypropanoate
  • tert-Butyl Carbamate &gt
  • tert-Butyl carbamate USP/EP/BP
  • t-Butoxycarbonylamide
  • tert-Butyl carbamate(TBCM)
  • BOC Amide pure, 98%
  • 1,1-Dimethylethyl carbamate
  • 4248-19-5
  • 79684-56-8
  • H2NCO2CCH33
  • NH2COOCCH33
  • Building Blocks
  • Protected Amines
  • Nitrogen Compounds
  • Organic Building Blocks
  • Protected Amino Acids
  • pharmacetical