(S)-5-Hydroxymethyldihydrofuran-2-one

Product Name: (S)-5-Hydroxymethyldihydrofuran-2-one
CAS No.: 32780-06-6
Chemical Name: (S)-5-Hydroxymethyldihydrofuran-2-one
Synonyms: 5-(Hydroxymethyl)dihydro-2(3H)-furanone;(S)-(+)-γ-Hydroxymethyl-γ(S)-Gamma-Hydroxymethyl-Gamma;(S)-4-HYDROXYMETHYL BUTYROLACTONE;(5S)-5-(hydroxyMethyl)oxolan-2-one;(s)-γ-hydroxymethyl-γ-butyrolactone;(S)-5-Hydroxymethyldihydrofuran-2-on;(S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE;(S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE
CBNumber: CB6702069
Molecular Formula: C5H8O3
Formula Weight: 116.12
MOL File: 32780-06-6.mol

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(S)-5-Hydroxymethyldihydrofuran-2-one Property

Melting point:: 72-74 °C
alpha: 56 º (c=3 in chloroform)
Boiling point:: 110-115 °C/0.2 mmHg (lit.)
Density: 1.237 g/mL at 25 °C (lit.)
refractive index: n20/D 1.471(lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
pka: 14.12±0.10(Predicted)
form: clear liquid
color: Colorless to Almost colorless
optical activity: [α]20/D +56°, c = 3 in chloroform
BRN: 1680284
CAS DataBase Reference: 32780-06-6(CAS DataBase Reference)
NIST Chemistry Reference: (S)-(+)-2',3'-dideoxyribonolactone(32780-06-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 23-24/25-37/39-26
WGK Germany: 3
HS Code: 29322090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 348902
Product name: (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone
Purity: 95%
Packaging: 1g
Price: $226
Updated: 2023/06/20

TCI Chemical

Product number: H0958
Product name: (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone
Purity: >94.0%(GC)
Packaging: 1g
Price: $114
Updated: 2024/03/01

TCI Chemical

Product number: H0958
Product name: (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone
Purity: >94.0%(GC)
Packaging: 5g
Price: $504
Updated: 2024/03/01

TRC

Product number: H973063
Product name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one
Packaging: 1g
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 119181
Product name: (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one
Purity: 95+%
Packaging: 1g
Price: $72
Updated: 2021/12/16

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(S)-5-Hydroxymethyldihydrofuran-2-one Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone can be used as a chiral synthon to synthesize:

Potent nucleoside, acetylcholine, and (+)-muricatacin analogs.
Mevinic acids, which are LDL cholesterol-lowering agents.
Adenine based anti-HIV agent named β-F-ddA.

General Description

Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a chiral building block widely used in the synthesis of many natural products and few biologically significant compounds like anti-HIV dideoxynucleosides. It is also used in the synthesis of optically active ligands.

(S)-5-Hydroxymethyldihydrofuran-2-one Preparation Products And Raw materials

Raw materials

Borane-methyl sulfide complex L-Glutamic acid Sodium nitrite Tetrahydrofuran Benzene Ethyl acetate Hydrochloric acid Methanol PETROLEUM ETHER

Preparation Products

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(S)-5-Hydroxymethyldihydrofuran-2-one Suppliers

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View Lastest Price from (S)-5-Hydroxymethyldihydrofuran-2-one manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: (S)-5-Hydroxymethyldihydrofuran-2-one 32780-06-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-01

Career Henan Chemical Co

Product: (S)-5-Hydroxymethyldihydrofuran-2-one 32780-06-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

32780-06-6, (S)-5-Hydroxymethyldihydrofuran-2-oneRelated Search:

Tris(hydroxymethyl)nitromethane Tetrahydrofuran (Hydroxymethyl)urea methylol cellulose Tris(hydroxymethyl)aminomethane Furazolidone BETA-BUTYROLACTONE 2,5-Dihydrofuran Methyl 2-hydroxyethyl cellulose Dihydromyrcenol 2,3-Dihydrobenzofuran 2,3-Dihydrofuran 2-Methylfuran 2-Hydroxyethyl methacrylate CARBOXYMETHYLCELLULOSE SODIUM SALT Trimethylolpropane Gamma Butyrolactone (1S)-(-)-Camphanic acid

(S)-(+)-gamma-Hydroxymethyl-gamma-butyrolactone,97%

(S)-Gamma-Hydroxymethyl-Gamma

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone ,97%

(5S)-5-(HYDROXYMETHYL)-3,4,5-TRIHYDROFURAN-2-ONE

(5S)-(+)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one

(S)-(+)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone (S)-(+)-5-Hydroxymethyltetrahydro-2-furanone

5-Oxo-tetrahydro-furan-2-carboxylic acid ethyl ester

(5S)-5-(hydroxyMethyl)oxolan-2-one

2(3H)-Furanone,dihydro-5-(hydroxyMethyl)-, (5S)-

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone 95%

(<i>S</i>)-(+)-&gamma

-Hydroxymethyl-&gamma

5-(Hydroxymethyl)dihydro-2(3H)-furanone

(S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE

(S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)FURANONE

(S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTON

(S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE

(S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE

(S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE

(S)-(+)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE

(S)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran

DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE (S-)

2(3H)-FURANONE, DIHYDRO-5-(HYDROXYMETHYL)-,(S)

(S)-4-HYDROXYMETHYL BUTYROLACTONE

(S)-5-HYDROXYMETHYL-2-OXOTETRAHYDROFURAN

(S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE

(S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE

(S)-(+)-5-HYDROXYMETHYLTETRAHYDRO-2-FURANONE

(S)-5-Hydroxymethyldihydrofuran-2-on

(S)-γ-Hydroxymethyl-γ-butyrolactone, (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran

(S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran

(S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)- FURANONE, 95% (98% EE/GLC)

(S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYRO- &

(s)-γ-hydroxymethyl-γ-butyrolactone

(S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE 98%

(S)-(+)-γ-Hydroxymethyl-γ-butyrolactone&gt

(5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone

32780-06-6

Asymmetric Synthesis

Chiral Building Blocks

Heterocyclic Building Blocks

Furans

chiral

Chiral Reagent