ChemicalBook > CAS DataBase List > N-Benzylpiperidine-4-carboxaldehyde
N-Benzylpiperidine-4-carboxaldehyde
Synthesis- Product Name
- N-Benzylpiperidine-4-carboxaldehyde
- CAS No.
- 22065-85-6
- Chemical Name
- N-Benzylpiperidine-4-carboxaldehyde
- Synonyms
- Benzylpiperidine-4-carboxaldehyde;1-Benzylpiperidine-4-carboxaldehyde;N-Benzyl-4-Piperidinecarboxaldehyde95%;N-Benzylpiperidine-4-carboxaldehyde 95%;1-(Phenylmethyl)-4-piperidinecarbaldehyde;1-(Phenylmethyl)-4-piperidinecarboxaldehyde;1-Benzyl-4-piperidinecarboxaldehyde,1-Benzyl-4-formylpiperidine;1-Benzyl-4-formylpiperidine, [(4-Formylpiperidin-1-yl)methyl]benzene;ZERO/005913;RSYY（Avanafil)-1
- CBNumber
- CB6703107
- Molecular Formula
- C13H17NO
- Formula Weight
- 203.28
- MOL File
- 22065-85-6.mol
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N-Benzylpiperidine-4-carboxaldehyde Property
- Melting point:
- 145-149 °C
- Boiling point:
- 315.4 °C/760 mmHg
- Density
- 1.026 g/mL at 25 °C
- refractive index
- n20/D 1.537
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Acetone (Slightly), Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sli
- form
- Liquid
- pka
- 8.04±0.10(Predicted)
- color
- Clear colorless to pale yellow
- Sensitive
- Air Sensitive
- InChIKey
- SGIBOXBBPQRZDM-UHFFFAOYSA-N
- CAS DataBase Reference
- 22065-85-6(CAS DataBase Reference)
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Safety
- Hazard Codes
- T
- Risk Statements
- 25-41
- Safety Statements
- 26-28-36/37/39
- RIDADR
- UN 2810 6.1/PG 3
- WGK Germany
- 3
- HazardClass
- IRRITANT
- PackingGroup
- Ⅲ
- HS Code
- 29333990
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 664081
- Product name
- N-Benzylpiperidine-4-carboxaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $67.4
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 664081
- Product name
- N-Benzylpiperidine-4-carboxaldehyde
- Purity
- 95%
- Packaging
- 5g
- Price
- $271
- Updated
- 2023/06/20
TCI Chemical
- Product number
- B3190
- Product name
- 1-Benzyl-4-piperidinecarboxaldehyde
- Purity
- >96.0%(GC)(T)
- Packaging
- 5g
- Price
- $65
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B3190
- Product name
- 1-Benzyl-4-piperidinecarboxaldehyde
- Purity
- >96.0%(GC)(T)
- Packaging
- 25g
- Price
- $209
- Updated
- 2024/03/01
TRC
- Product number
- B288620
- Product name
- 1-Benzyl-4-piperidine-carboxaldehyde
- Packaging
- 25g
- Price
- $540
- Updated
- 2021/12/16
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N-Benzylpiperidine-4-carboxaldehyde Chemical Properties,Usage,Production
Synthesis
A round
bottom flask was charged with oxalyl chloride (16.2 g, 0.12
mol), dichloromethane (150 mL) and anhydrous dimethyl sulfoxide
(20 mL). Stir the reaction mixture mass in a cryo bath at -70 °C
for 15 min. The resulting mixture is charged dropwise with N-benzyl piperidine alcohol 3 (20 g, 0.097 mol), along with
triethylamine (24.6 g, 0.24 mol) and continued stirring for the
next 15 min. After that, the mass is allowed to attain room
temperature overnight, then diluted with dichloromethane (100
mL) and quenched with cold water. The organic layer was
washed subsequently with 5 % HCl solution, brine solution, 5
% sodium bicarbonate solution and dried over sodium sulfate.
Toluene was removed in vacuo to afford N-Benzylpiperidine-4-carboxaldehyde (19.2 g, 96 %).
Chemical Properties
Colorless Oil
Uses
Reactant for:
- Stereospecific allylic alkylation
- Reactions of Grignard reagents with carbonyl compounds
- Fluorodenitrations and nitrodehalogenations for labeled PET ligands and fluoropharmaceuticals
- Selective α1 receptor antagonists
Reactant for synthesis of:
- Donepezil
- MCH-R1 antagonists
N-Benzylpiperidine-4-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-Benzylpiperidine-4-carboxaldehyde manufacturers
Hebei Duling International Trade Co. LTD
- Product
- N-Benzylpiperidine-4-carboxaldehyde 22065-85-6
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-02-22
Henan Aochuang Chemical Co.,Ltd.
- Product
- N-Benzylpiperidine-4-carboxaldehyde 22065-85-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-17
Qiuxian Baitai New Material Co., LTD
- Product
- N-Benzylpiperidine-4-carboxaldehyde 22065-85-6
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 500ton/Month
- Release date
- 2021-12-21
22065-85-6, N-Benzylpiperidine-4-carboxaldehydeRelated Search:
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