(S)-AMPA

Product Name: (S)-AMPA
CAS No.: 83643-88-3
Chemical Name: (S)-AMPA
Synonyms: AMQ;(S)-AMPA;glutamate-AMPA;L-AMPA, S-AMPA;(S) AMPA,(S)AMPA;(S)-AMPA (mM/ml);(S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio;(S)-amino-3-hydroxy-5-methylisoxazolepropionic acid;(S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI;(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid
CBNumber: CB6711838
Molecular Formula: C7H10N2O4
Formula Weight: 186.17
MOL File: 83643-88-3.mol

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(S)-AMPA Property

alpha: D28 -21 ±2° (c = 0.19 in water)
Density: 1.386±0.06 g/cm3(Predicted)
storage temp.: Store at RT
form: White to off-white powder.
pka: 2.15±0.10(Predicted)
color: White
Water Solubility: Soluble to 100 mM in water
CAS DataBase Reference: 83643-88-3(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A0326
Product name: (S)-AMPA
Purity: ≥98%
Packaging: 1mg
Price: $246
Updated: 2024/03/01

Sigma-Aldrich

Product number: A0326
Product name: (S)-AMPA
Purity: ≥98%
Packaging: 5mg
Price: $847
Updated: 2024/03/01

Alfa Aesar

Product number: J65847
Product name: (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Packaging: 5mg
Price: $176
Updated: 2021/12/16

Tocris

Product number: 0254
Product name: (S)-AMPA
Purity: ≥99%(HPLC)
Packaging: 10
Price: $279
Updated: 2021/12/16

Tocris

Product number: 0254
Product name: (S)-AMPA
Purity: ≥99%(HPLC)
Packaging: 50
Price: $1109
Updated: 2021/12/16

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(S)-AMPA Chemical Properties,Usage,Production

Uses

Active enantiomer of AMPA that induces apoptosis in cortical neurons

Uses

(S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice.

Uses

(S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor.

General Description

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC).

Biological Activity

Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ .

Biochem/physiol Actions

Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors.

storage

Room temperature

(S)-AMPA Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-AMPA Suppliers

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83643-88-3, (S)-AMPARelated Search:

AMPA (RS)-AMPA HYDROBROMIDE,AMPA HYDROBROMIDE,AMPA,(+/-)-AMPA HYDROBROMIDE CNQX 5-Methylisoxazole ETHYL 2-ACETAMIDO-2-ETHOXYCARBONYL-3-[3-(ETHOXYCARBONYLMETHOXY)-5-METHYLISOXAZOL-4-YL]PROPANOATE (S)-AMPA QUADRAPURE(TM) AMPA WILLARDIINE, S(-)-5-FLUORO POTENT AMPA/K AINATE A FMOC-R-AMPA-OH ETHYL 2-ACETAMIDO-2-ETHOXYCARBONYL-3-[3-HYDROXY-5-METHYLISOXAZOL-4-YL]PROPANOATE AMPA,(RS)-AMPA,AMPA (ZWITTERION) POTENT EXCITATORY AMI,AMPA HBR AMPA-FMOC S(-)-WILLARDIINE AMPA/KAINATE AGONIST (R)-AMPA,(R)-AMPA ZWITTERION AMPA,AMPA HYDRATE,(RS)-AMPA Anti-Glutamate Receptor AMPA R1 (GluR1) antibody produced in rabbit AMPA 13C 15N AMPA receptor-binding protein ABP

(S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID

(S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID

(S)-ALPHA-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID

(S)-AMPA

(S)-amino-3-hydroxy-5-methylisoxazolepropionic acid

(S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio

(S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI

(s)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid

(2S)-2-amino-3-(5-methyl-3-oxo-4-isoxazolyl)propanoic acid

(S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazol-propionic acid

(2S)-2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid

(2S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid

(2S)-2-amino-3-(3-keto-5-methyl-isoxazol-4-yl)propionic acid

(2S)-2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid

(2S)-2-azanyl-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid

(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid

(S)-2-aMino-3-(3-hydroxy-5-Methylisoxazol-4-yl)propanoic acid

(S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid

AMQ

AMQ;GLUTAMATE-AMPA;(S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID

glutamate-AMPA

4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (αS)-

(S)-2-Amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid

L-AMPA, S-AMPA

(S) AMPA,(S)AMPA

(S)-AMPA (mM/ml)

83643-88-3

C7H10NO5

BioChemical

Cell Signaling and Neuroscience

Cell Biology

Ionotropic Glutamate Receptor Modulators

Ion Channels

Ligand-Gated Ion Channels

Glutamate receptor

Apoptosis Inducers

Glutamate