N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE

Product Name: N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE
CAS No.: 181629-93-6
Chemical Name: N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE
Synonyms: SB 228357;SB-228357,SB228357;N-[3-fluoro-5-(3-pyridinyl)phenyl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide;N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE;N-[3-Fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole-1-carboxamide;1H-Indole-1-carboxamide, N-[3-fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-
CBNumber: CB6716853
Molecular Formula: C22H17F4N3O2
Formula Weight: 431.38
MOL File: 181629-93-6.mol

More

Less

N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Property

Boiling point:: 625.4±55.0 °C(Predicted)
Density: 1.398±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ~8 mg/mL, soluble
form: solid
pka: 9.72±0.70(Predicted)
color: white

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 1375
Product name: SB228357
Purity: ≥99%(HPLC)
Packaging: 10
Price: $153
Updated: 2021/12/16

Tocris

Product number: 1375
Product name: SB228357
Purity: ≥99%(HPLC)
Packaging: 50
Price: $643
Updated: 2021/12/16

Usbiological

Product number: 465900
Product name: SB 228357
Packaging: 10mg
Price: $453
Updated: 2021/12/16

TRC

Product number: S155035
Product name: SB228357
Packaging: 25mg
Price: $305
Updated: 2021/12/16

ChemScene

Product number: CS-0024682
Product name: SB228357
Purity: >99.0%
Packaging: 5mg
Price: $360
Updated: 2021/12/16

More

Less

N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Chemical Properties,Usage,Production

Uses

SB 228357 is a SR-2C/SR-2B receptor antagonist. It is used in the treatment of irritable bowel syndrome (IBS).

Definition

ChEBI: SB 228357 is an indolyl carboxylic acid.

Biological Activity

5-HT 2C/2B receptor antagonist (pK i values are 7.0, 8.1 and 9.1 at 5-HT 2A , 2B and 2C receptors respectively). Displays inverse agonism in a 5-HT-stimulated PI hydrolysis model of 5-HT 2C receptor function. Orally active in vivo .

storage

Store at RT

N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE Suppliers

China 27 Germany 1 Switzerland 1 United Kingdom 4 United States 9 Global 42

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32063
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

cjbscvictory

Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10000
Advantage: 58

Hebei Weite Medical Technology Co., Ltd

Tel: 13180081292
Email: contact@wetogethermed.com
Country: China
ProdList: 7387
Advantage: 58

Nantong Hi-Future Biotechnology Co., Ltd

Tel: 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 3056
Advantage: 58

181629-93-6, N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDERelated Search:

6-METHYL-2,3-DIHYDRO-1H-INDOLE 3-Fluoro-5-methylaniline N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE 5-AMINO-2-METHOXYBENZOTRIFLUORIDE 3-Pyridin-3-ylaniline alpha,alpha,alpha-Trifluoro-o-cresol 2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE 4-Amino-2,5-dimethylphenol 4-AMINO-2-(TRIFLUOROMETHYL)PHENOL 6-(Trifluoromethyl)indoline 2-(TRIFLUOROMETHYL)ANISOLE

N-[3-FLUORO-5-(3-PYRINDYL)PHENYL]-2,3-DIHYDRO-5-METHOXY-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE

SB 228357

N-[3-Fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole-1-carboxamide

N-[3-fluoro-5-(3-pyridinyl)phenyl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide

1H-Indole-1-carboxamide, N-[3-fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-

SB-228357,SB228357

181629-93-6

C22H17F4N3O2