ChemicalBook > CAS DataBase List > 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE

1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE

Product Name
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE
CAS No.
102120-87-6
Chemical Name
1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE
Synonyms
4,4'-(ethane-1,1-diyl)bis(isobutylbenzene);IBUPROFEN IMPURITY R;IBuprofen Impurity 18;Ibuprofen EP Impurity R;1,1-Bis(p-isobutylphenyl)ethane;1,1-Bis-(4-isobutylphenyl)ethane;1,1'-(Ethane-1,1-diyl)-4,4'-(2-meth;Ibuprofen EP Impurity R:Ibuprofen Impurity R;Ibuprofen Impurity 18(Ibuprofen EP Impurity R);Benzene, 1,1'-ethylidenebis[4-(2-methylpropyl)-
CBNumber
CB6717719
Molecular Formula
C22H30
Formula Weight
294.47
MOL File
102120-87-6.mol
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1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Property

Boiling point:
174-184 °C(Press: 2-3 Torr)
Density 
0.924±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Acetonitrile (Slightly), Chloroform, Methanol (Slightly)
form 
Oil
color 
Colourless
Major Application
pharmaceutical
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Safety

WGK Germany 
WGK 3
Storage Class
10 - Combustible liquids
Hazard Classifications
Acute Tox. 4 Oral
Aquatic Chronic 4
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1982
Product name
Ibuprofen Impurity R
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50mg
Price
$778
Updated
2025/07/31
TRC
Product number
B448875
Product name
1,1-Bis(p-isobutylphenyl)ethane
Packaging
1g
Price
$1295
Updated
2021/12/16
Biosynth Carbosynth
Product number
IB171023
Product name
1,1-Bis(p-isobutylphenyl)ethane
Packaging
1g
Price
$1650
Updated
2021/12/16
Biosynth Carbosynth
Product number
IB171023
Product name
1,1-Bis(p-isobutylphenyl)ethane
Packaging
500mg
Price
$1000
Updated
2021/12/16
Biosynth Carbosynth
Product number
IB171023
Product name
1,1-Bis(p-isobutylphenyl)ethane
Packaging
50mg
Price
$200
Updated
2021/12/16
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1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Chemical Properties,Usage,Production

Uses

1,1-Bis(p-isobutylphenyl)ethane (Ibuprofen EP Impurity R) is an impurity in the synthesis of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.

1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1-BIS-(4-ISOBUTYLPHENYL)ETHANE Suppliers

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102120-87-6, 1,1-BIS-(4-ISOBUTYLPHENYL)ETHANERelated Search:


  • IBUPROFEN IMPURITY R
  • 1,1-Bis(p-isobutylphenyl)ethane
  • IBuprofen Impurity 18
  • Ibuprofen EP Impurity R
  • 1,1-Bis(p-isobutylphenyl)ethane(Ibuprofen EP Impurity R)
  • Ibuprofen EP Impurity R:Ibuprofen Impurity R
  • 1,1'-(Ethane-1,1-diyl)-4,4'-(2-meth
  • Benzene, 1,1'-ethylidenebis[4-(2-methylpropyl)-
  • Ibuprofen Impurity 18(Ibuprofen EP Impurity R)
  • 4,4'-(ethane-1,1-diyl)bis(isobutylbenzene)
  • 1-(2-methylpropyl)-4-[1-[4-(2-methylpropyl)phenyl]ethyl]benzene
  • 4,4'-(Ethane-1,1-diyl)bis(isobutylbenzene) (Ibuprofen Impurity)
  • 1,1-Bis-(4-isobutylphenyl)ethane
  • 1,1'-(Ethane-1,1-diyl)-4,4'-(2-methylpropyl)dibenzene
  • Ibuprofen Imp. R (EP): 1,1'-(ethane-1,1-diyl)-4,4'-(2-methylpropyl)dibenzene.
  • 102120-87-6