ChemicalBook > CAS DataBase List > 4-Hydroxy-3-methoxybenzylamine hydrochloride

4-Hydroxy-3-methoxybenzylamine hydrochloride

Product Name
4-Hydroxy-3-methoxybenzylamine hydrochloride
CAS No.
7149-10-2
Chemical Name
4-Hydroxy-3-methoxybenzylamine hydrochloride
Synonyms
VANILLYLAMINE HCL;)-2-methoxyphenoL;TIMTEC-BB SBB003667;Vanillin hydrochloride;vanillylammonium chloride;Vanilylamine hydrochloride;Vanillyamine hydrochloride;VANILLYLAMINE HYDROCHLORIDE;4-AMINOMETHYL-2-METHOXYPHENO;α-Aminocreosol Hydrochloride
CBNumber
CB6722621
Molecular Formula
C8H12ClNO2
Formula Weight
189.64
MOL File
7149-10-2.mol
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4-Hydroxy-3-methoxybenzylamine hydrochloride Property

Melting point:
219-221 °C (dec.)(lit.)
storage temp. 
Store below +30°C.
solubility 
DMSO (Slightly, Heated), Methanol (Slightly)
form 
Powder
color 
Off-white
Sensitive 
Moisture Sensitive
BRN 
3915418
Stability:
Hygroscopic
InChI
InChI=1S/C8H11NO2.ClH/c1-11-8-4-6(5-9)2-3-7(8)10;/h2-4,10H,5,9H2,1H3;1H
InChIKey
PUDMGOSXPCMUJZ-UHFFFAOYSA-N
SMILES
C1(OC)=C(O)C=CC(CN)=C1.Cl
LogP
5.4 at 30℃
CAS DataBase Reference
7149-10-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29214990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H36605
Product name
4-Hydroxy-3-methoxybenzylamine hydrochloride
Purity
98%
Packaging
1g
Price
$46.5
Updated
2025/07/31
Sigma-Aldrich
Product number
8.41494
Product name
4-Hydroxy-3-methoxybenzylamine hydrochloride
Purity
for synthesis
Packaging
1G
Price
$43.8
Updated
2023/01/07
TCI Chemical
Product number
A2330
Product name
4-(Aminomethyl)-2-methoxyphenol Hydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$31
Updated
2025/07/31
TCI Chemical
Product number
A2330
Product name
4-(Aminomethyl)-2-methoxyphenol Hydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$99
Updated
2025/07/31
Usbiological
Product number
022736
Product name
Vanillylamine Hydrochloride
Packaging
5g
Price
$425
Updated
2021/12/16
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4-Hydroxy-3-methoxybenzylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

A metabolite of Capsaicin.

Synthesis

2874-33-1

7149-10-2

The preparation method of the present invention for the preparation of vanillin amine hydrochloride is described in detail in the following steps: A, 4-hydroxy-3-methoxybenzaldehyde oxime was used as raw material, and ethanol was used as solvent; firstly, 133.6 g (0.80 mol) of 4-hydroxy-3-methoxybenzaldehyde oxime was added into a 2L three-necked flask fitted with a stirrer and a thermometer, and then 1,400mL of ethanol and 13.0 g of an aluminum-zinc Nickel composite catalyst, under the condition of passing hydrogen for protection, heating to 40°C, the reaction for 8 hours; B, after the completion of the reaction filtration (the filtrate residue is the unreacted catalyst, can be recycled), in the filtrate add 70mL of hydrochloric acid with a mass concentration of 30%, adjusting the filtrate pH to 1, precipitated white crystals, filtration to isolate the white crystals, drying in vacuum, to obtain vanillin amine hydrochloride 136.8 g, yield 90.5%.

References

[1] Polymer, 2011, vol. 52, # 9, p. 1908 - 1916
[2] Journal of Organic Chemistry, 1988, vol. 53, # 5, p. 1064 - 1071
[3] Patent: CN106366004, 2017, A. Location in patent: Paragraph 0017-0028
[4] Patent: JP2005/527478, 2005, A. Location in patent: Page/Page column 4
[5] Russian Chemical Bulletin, 2018, vol. 67, # 8, p. 1394 - 1400

4-Hydroxy-3-methoxybenzylamine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy-3-methoxybenzylamine hydrochloride Suppliers

Taizhou Chuangyuan Industrial Technology Co. Ltd.
Tel
13757609826
Email
sales@tzchemical.com
Country
China
ProdList
216
Advantage
58
Hangzhou Great Forest Biomedical Ltd.
Tel
0571-28313180 17767135330
Fax
0571-28313182
Email
info@great-forest.com
Country
China
ProdList
54
Advantage
58
Shandong Luteida Chemical Co., Ltd.
Tel
155-08613825 15508613825
Email
137739947@qq.com
Country
China
ProdList
57
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58
WEIFANG CYANOCHEM CO; LTD.
Tel
0571-85220831 13188860031
Fax
+86 571 85220831
Email
476521632@qq.com
Country
China
ProdList
297
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Shanghai Targsense Scientific Co., Ltd.
Tel
18916626092
Email
targsense@qq.com
Country
China
ProdList
110
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65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
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View Lastest Price from 4-Hydroxy-3-methoxybenzylamine hydrochloride manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Hydroxy-3-methoxybenzylamine hydrochloride 7149-10-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Chuanghai Biotechnology Co., Ltd
Product
VanillylaMine hydrochloride 7149-10-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Hydroxy-3-methoxybenzylamine hydrochloride 7149-10-2
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-22

7149-10-2, 4-Hydroxy-3-methoxybenzylamine hydrochlorideRelated Search:


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