ChemicalBook > CAS DataBase List > 4-Hydroxy-3-methoxybenzylamine hydrochloride

4-Hydroxy-3-methoxybenzylamine hydrochloride

Product Name
4-Hydroxy-3-methoxybenzylamine hydrochloride
CAS No.
7149-10-2
Chemical Name
4-Hydroxy-3-methoxybenzylamine hydrochloride
Synonyms
VANILLYLAMINE HCL;)-2-methoxyphenoL;TIMTEC-BB SBB003667;Vanillin hydrochloride;vanillylammonium chloride;Vanilylamine hydrochloride;Vanillyamine hydrochloride;VANILLYLAMINE HYDROCHLORIDE;4-AMINOMETHYL-2-METHOXYPHENO;α-Aminocreosol Hydrochloride
CBNumber
CB6722621
Molecular Formula
C8H12ClNO2
Formula Weight
189.64
MOL File
7149-10-2.mol
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4-Hydroxy-3-methoxybenzylamine hydrochloride Property

Melting point:
219-221 °C (dec.)(lit.)
storage temp. 
Store below +30°C.
solubility 
DMSO (Slightly, Heated), Methanol (Slightly)
form 
Powder
color 
Off-white
Sensitive 
Moisture Sensitive
BRN 
3915418
Stability:
Hygroscopic
InChI
InChI=1S/C8H11NO2.ClH/c1-11-8-4-6(5-9)2-3-7(8)10;/h2-4,10H,5,9H2,1H3;1H
InChIKey
PUDMGOSXPCMUJZ-UHFFFAOYSA-N
SMILES
C1(OC)=C(O)C=CC(CN)=C1.Cl
LogP
5.4 at 30℃
CAS DataBase Reference
7149-10-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29214990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H36605
Product name
4-Hydroxy-3-methoxybenzylamine hydrochloride
Purity
98%
Packaging
1g
Price
$46.5
Updated
2025/07/31
Sigma-Aldrich
Product number
8.41494
Product name
4-Hydroxy-3-methoxybenzylamine hydrochloride
Purity
for synthesis
Packaging
1G
Price
$43.8
Updated
2023/01/07
TCI Chemical
Product number
A2330
Product name
4-(Aminomethyl)-2-methoxyphenol Hydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$31
Updated
2025/07/31
TCI Chemical
Product number
A2330
Product name
4-(Aminomethyl)-2-methoxyphenol Hydrochloride
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$99
Updated
2025/07/31
Usbiological
Product number
022736
Product name
Vanillylamine Hydrochloride
Packaging
5g
Price
$425
Updated
2021/12/16
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4-Hydroxy-3-methoxybenzylamine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

A metabolite of Capsaicin.

Synthesis

2874-33-1

7149-10-2

The preparation method of the present invention for the preparation of vanillin amine hydrochloride is described in detail in the following steps: A, 4-hydroxy-3-methoxybenzaldehyde oxime was used as raw material, and ethanol was used as solvent; firstly, 133.6 g (0.80 mol) of 4-hydroxy-3-methoxybenzaldehyde oxime was added into a 2L three-necked flask fitted with a stirrer and a thermometer, and then 1,400mL of ethanol and 13.0 g of an aluminum-zinc Nickel composite catalyst, under the condition of passing hydrogen for protection, heating to 40°C, the reaction for 8 hours; B, after the completion of the reaction filtration (the filtrate residue is the unreacted catalyst, can be recycled), in the filtrate add 70mL of hydrochloric acid with a mass concentration of 30%, adjusting the filtrate pH to 1, precipitated white crystals, filtration to isolate the white crystals, drying in vacuum, to obtain vanillin amine hydrochloride 136.8 g, yield 90.5%.

References

[1] Polymer, 2011, vol. 52, # 9, p. 1908 - 1916
[2] Journal of Organic Chemistry, 1988, vol. 53, # 5, p. 1064 - 1071
[3] Patent: CN106366004, 2017, A. Location in patent: Paragraph 0017-0028
[4] Patent: JP2005/527478, 2005, A. Location in patent: Page/Page column 4
[5] Russian Chemical Bulletin, 2018, vol. 67, # 8, p. 1394 - 1400

4-Hydroxy-3-methoxybenzylamine hydrochloride Preparation Products And Raw materials

Raw materials

Ethanol Ammonium formate Hydrochloric acid Vanillin

Preparation Products

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View Lastest Price from 4-Hydroxy-3-methoxybenzylamine hydrochloride manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Hydroxy-3-methoxybenzylamine hydrochloride 7149-10-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Chuanghai Biotechnology Co., Ltd
Product
VanillylaMine hydrochloride 7149-10-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Hydroxy-3-methoxybenzylamine hydrochloride 7149-10-2
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-22

7149-10-2, 4-Hydroxy-3-methoxybenzylamine hydrochlorideRelated Search:

4-Hydroxyaniline hydrochloride Cysteamine hydrochloride ETHANOLAMINE HYDROCHLORIDE Phenoxybenzamine hydrochloride DL-Octopamine hydrochloride Methoxyammonium chloride 4-Fluorobenzylamine CHLOROPHOSPHONAZO III Trimethoprim Topotecan hydrochloride Cyclohexylamine hydrochloride Benzylamine hydrochloride DIETHANOLAMINE HYDROCHLORIDE Vanillin 2-Aminoethylammonium chloride Anisodamine Geranyl linalool (+)-B-HYDRASTINE HCL

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  • N-VANILLYLAMINE HYDROCHLORIDE CAS NO.: 7149-10-2
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  • 4-(aminomethyl)-2-methoxy-Phenol hydrochloride (1:1)
  • 7149-10-2
  • 1917434
  • 1917-43-4
  • C8H11NO2HCl
  • HOC6H3OCH3CH2NH2HCl
  • Organic Building Blocks
  • Oxygen Compounds
  • Building Blocks
  • Amino Alcohols
  • Amines, Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Chemical Amines
  • Anilines, Aromatic Amines and Nitro Compounds
  • Pharmaceutical Raw Materials
  • Chemical intermediate for Capsaicine