3-Bromo-2-pyridinamine
- Product Name
- 3-Bromo-2-pyridinamine
- CAS No.
- 13534-99-1
- Chemical Name
- 3-Bromo-2-pyridinamine
- Synonyms
- 3-BROMOPYRIDIN-2-AMINE;2-AMINO-3-BROMOPYRIDINE;IFLAB-BB F1371-0194;TIMTEC-BB SBB005538;3-Bromo-2-pyridimine;3-BROMO-2-PYRIDINAMINE;3-Bromopyridine-2-amine;2-Pyridinamine, 3-bromo-;3-BROMO-PYRIDIN-2-YLAMINE;2-AMINO-3-BROMOPYRIDINE 97%
- CBNumber
- CB6758910
- Molecular Formula
- C5H5BrN2
- Formula Weight
- 173.01
- MOL File
- 13534-99-1.mol
3-Bromo-2-pyridinamine Property
- Melting point:
- 63-67 °C
- Boiling point:
- 232.0±20.0 °C(Predicted)
- Density
- 1.6065 (rough estimate)
- vapor pressure
- 0.83-1.8Pa at 20-25℃
- refractive index
- 1.5182 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Powder
- pka
- 4.14±0.36(Predicted)
- color
- Gray to brown
- BRN
- 109867
- InChI
- InChI=1S/C5H5BrN2/c6-4-2-1-3-8-5(4)7/h1-3H,(H2,7,8)
- InChIKey
- RBCARPJOEUEZLS-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=CC=C1Br
- LogP
- 1.5 at 20℃ and pH7
- CAS DataBase Reference
- 13534-99-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 553719
- Product name
- 2-Amino-3-bromopyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $49.1
- Updated
- 2025/07/31
- Product number
- 553719
- Product name
- 2-Amino-3-bromopyridine
- Purity
- 97%
- Packaging
- 25g
- Price
- $223
- Updated
- 2025/07/31
- Product number
- A3551
- Product name
- 3-Bromopyridin-2-amine
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $86
- Updated
- 2025/07/31
- Product number
- A3551
- Product name
- 3-Bromopyridin-2-amine
- Purity
- min. 98.0 %
- Packaging
- 25G
- Price
- $258
- Updated
- 2025/07/31
- Product number
- A602073
- Product name
- 2-Amino-3-bromopyridine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
3-Bromo-2-pyridinamine Chemical Properties,Usage,Production
Chemical Properties
grey to brown powder
Uses
2-Amino-3-bromopyridine may be used to synthesize:
- 2-acylamido-3-bromopyridines
- 2-anilino-3-bromopyridine
- 3-[(2-methoxyphenyl)ethynyl]pyridin-2-amine
- 3-[(4-methoxyphenyl)ethynyl]pyridin-2-amine
- N-(bromopyridyl)amidines
- carbolines via palladium catalyzed arylation followed by palladium catalyzed amination reaction
- 2-amino-3-cyanopyridine via palladium catalyzed cyanation reaction with potassium ferro-cyanide in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene [DBU]
- nitro-substituted N,N′-dipyridinylamines via palladium catalyzed coupling reaction with 2-chloro-3-nitropyridine in the presence of Xantphos ligand
- 2-amino-3-iodopyridine via reaction with sodium iodide in the presence of copper(I)iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine
Synthesis
697300-73-5
13534-99-1
General procedure for the synthesis of 2-amino-3-bromopyridine from 3-bromo-5-iodopyridin-2-amine: 30 g of 3-bromo-5-iodopyridin-2-amine and 300 ml of ethanol were added to a reaction flask with 1 g of palladium/silica catalyst. The air in the reaction flask was first replaced three times with nitrogen and then three times with hydrogen. The reaction pressure was adjusted from 0.05 MPa to 0.1 MPa and the reaction temperature was controlled between 20 °C and 30 °C until the raw materials were completely reacted. After the reaction was completed, the catalyst was recovered by filtration. The reaction solution was concentrated to remove some of the solvent and diluted by adding 300 ml of water. Subsequently, 4.2 g of sodium hydroxide was added for neutralization and cooled to 0 °C to 5 °C. The precipitated solid was filtered and dried to give 16.8 g of 3-bromopyridin-2-amine in 97% yield.
References
[1] Patent: CN106432068, 2017, A. Location in patent: Paragraph 0037; 0039; 0040; 0041
3-Bromo-2-pyridinamine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-2-pyridinamine Suppliers
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- nfo@matrix-fine-chemicals.com
- Country
- Switzerland
- ProdList
- 6968
- Advantage
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- Switzerland
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View Lastest Price from 3-Bromo-2-pyridinamine manufacturers
- Product
- 3-Bromo-2-pyridinamine 13534-99-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-20
- Product
- 3-Bromo-2-pyridinamine 13534-99-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-12
- Product
- 3-Bromo-2-pyridinamine 13534-99-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-12-22