ChemicalBook > CAS DataBase List > 5-Nitrofluorescein

5-Nitrofluorescein

Product Name
5-Nitrofluorescein
CAS No.
27402-68-2
Chemical Name
5-Nitrofluorescein
Synonyms
Nitrofluorescein;5-NITROFLUORESCEIN;6-NITROFLUORESCEIN;5-NITROFLUOROESCEIN;5-NITRO FLUORESCEIN 98+%;NITROFLUORESCEIN, ISOMER 2;6-Nitrofluorescein (isomer II);6-Nitrofluorescein(isomerII)>3',6'-dihydroxy-6-nitro-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;3',6'-Dihydroxy-6-nitro-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
CBNumber
CB6762401
Molecular Formula
C20H11NO7
Formula Weight
377.3
MOL File
27402-68-2.mol
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5-Nitrofluorescein Property

solubility 
Acetone, Methanol
form 
Solid
color 
Orange Cyrstalline
Stability:
Light and Moisture Sensitive
InChI
InChI=1S/C20H11NO7/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)20(14)16-7-10(21(25)26)1-4-13(16)19(24)28-20/h1-9,22-23H
InChIKey
GYWGQAIDMYGOLU-UHFFFAOYSA-N
SMILES
C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC([N+]([O-])=O)=C1)C(=O)O2
EPA Substance Registry System
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-6-nitro- (27402-68-2)
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Safety

HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
N0445
Product name
6-Nitrofluorescein (isomer II)
Purity
>98.0%(T)
Packaging
1g
Price
$208
Updated
2024/03/01
TCI Chemical
Product number
N0445
Product name
6-Nitrofluorescein (isomer II)
Purity
>98.0%(T)
Packaging
5g
Price
$678
Updated
2024/03/01
Usbiological
Product number
N2592-45A
Product name
Nitrofluorescein, Isomer 2
Packaging
1g
Price
$425
Updated
2021/12/16
Usbiological
Product number
285231
Product name
Nitrofluorescein, isomer 2
Packaging
500mg
Price
$432
Updated
2021/12/16
TRC
Product number
N495863
Product name
Nitrofluorescein,Isomer2
Packaging
500mg
Price
$95
Updated
2021/12/16
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5-Nitrofluorescein Chemical Properties,Usage,Production

Chemical Properties

Orange Cyrstalline Solid

Uses

Fluorescent labeling reagent for proteins, 6-Nitrofluorescein can be used in the fluorescent antibody technique for rapid identification of pathogens.

Preparation

5-Nitrofluorescein (3′,6′-dihydroxy-6-nitrospiro[2-benzofuran-3,9′-xanthene]-1-one) is a key intermediate in the synthesis of various fluorescent compounds such as 5-aminofluorescein (5-amino-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one), fluorescein 5-isothiocyanate (FITC; 3′,6′-dihydroxy-5-isothiocyanato-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one), and fluorescein lisicol (previously known as cholyl-lysylfluorescein or CLF.
Process for the preparation of 5-/6-nitrofluorescein(US20120220787A1)

5-Nitrofluorescein Preparation Products And Raw materials

Raw materials

Preparation Products

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