Methyl 2-bromomethyl-3-methoxybenzoate
- Product Name
- Methyl 2-bromomethyl-3-methoxybenzoate
- CAS No.
- 71887-28-0
- Chemical Name
- Methyl 2-bromomethyl-3-methoxybenzoate
- Synonyms
- METHYL 2-BROMOMETHYL-3-METHOXY-BENZOATE;2-Bromomethyl-3-methoxybenzoic acid methyl ester;Benzoic acid, 2-(bromomethyl)-3-methoxy-, methyl ester
- CBNumber
- CB6767264
- Molecular Formula
- C10H11BrO3
- Formula Weight
- 259.1
- MOL File
- 71887-28-0.mol
Methyl 2-bromomethyl-3-methoxybenzoate Property
- Melting point:
- 112-114 °C(Solv: hexane (110-54-3))
- Boiling point:
- 330.0±32.0 °C(Predicted)
- Density
- 1.432
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- J15272
- Product name
- Methyl2-bromomethyl-3-methoxybenzoate
- Purity
- 97%
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 7381AH
- Product name
- Methyl2-bromomethyl-3-methoxybenzoate
- Packaging
- 250mg
- Price
- $123
- Updated
- 2021/12/16
- Product number
- J15272
- Product name
- Methyl2-bromomethyl-3-methoxybenzoate
- Purity
- 97%
- Packaging
- 5g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 7381AH
- Product name
- Methyl2-bromomethyl-3-methoxybenzoate
- Packaging
- 1g
- Price
- $213
- Updated
- 2021/12/16
- Product number
- HCH0142425
- Product name
- METHYL-2-BROMOMETHYL-3-METHOXY-BENZOATE
- Purity
- 98.00%
- Packaging
- 5MG
- Price
- $502.73
- Updated
- 2021/12/16
Methyl 2-bromomethyl-3-methoxybenzoate Chemical Properties,Usage,Production
Synthesis
42981-93-1
71887-28-0
General procedure for the synthesis of methyl 2-bromomethyl-3-methoxybenzoate from methyl 3-methoxy-2-methylbenzoate: to a solution of CHCl3 (2-5 mL/mmol) or CCl4 (5 mL/mmol) containing methyl 3-methoxy-2-methylbenzoate (1.00 eq.), N-bromosuccinimide (NBS, 1.10- 2.20 eq.) and azobisisobutyronitrile (AIBN, 0.02-0.04 eq.). The reaction mixture was heated to reflux for 2-22 hours and subsequently cooled to room temperature. Upon completion of the reaction, the solvent is removed by evaporation under reduced pressure if CHCl3 is used as solvent, or by distillation if CCl4 is used, to give the target product methyl 2-bromomethyl-3-methoxybenzoate. Precautions: CHCl3 and CCl4 are highly toxic and carcinogenic, protective gloves should be worn and the operation should be carried out in a fume hood.
References
[1] Tetrahedron, 2018, vol. 74, # 2, p. 224 - 239
[2] Journal of Organic Chemistry, 1980, vol. 45, # 1, p. 12 - 15
[3] Patent: WO2004/26875, 2004, A1. Location in patent: Page 38
[4] Patent: US2004/106791, 2004, A1. Location in patent: Page 9
[5] Chinese Chemical Letters, 2012, vol. 23, # 1, p. 9 - 12
Methyl 2-bromomethyl-3-methoxybenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 2-bromomethyl-3-methoxybenzoate Suppliers
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