Tomatidine hydrochloride

Product Name: Tomatidine hydrochloride
CAS No.: 6192-62-7
Chemical Name: Tomatidine hydrochloride
Synonyms: TOMATIDINE HCL;TOMATIDINE HCL(RG);TOMATIDINE HYDROCHLORIDE;Tomatidine hydrochloride-RM;ToMatidin Hydrochloride, >85%;Tomatidine Hydrochloride, >5alpha-Tomatidan-3beta-ol HCl;Tomatidine, Hydrochloride, >85%;5α-Tomatidan-3β-ol hydrochloride;SPIRPSOLAN-3-OL-(3B,5A,22B,25C) HCL
CBNumber: CB6774105
Molecular Formula: C27H46ClNO2
Formula Weight: 452.11
MOL File: 6192-62-7.mol

More

Less

Tomatidine hydrochloride Property

Melting point:: 281-284°C (dec.)
storage temp.: 2-8°C
solubility: Methanol (Slightly)
form: Off-white solid
color: White to Off-White
BRN: 3920740

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T2909
Product name: Tomatidine hydrochloride
Purity: ≥85%
Packaging: 25mg
Price: $75.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL80003
Product name: Tomatidine hydrochloride
Purity: phyproof? Reference Substance
Packaging: 20MG
Price: $328
Updated: 2023/01/07

Sigma-Aldrich

Product number: 614350
Product name: Tomatidine, HCl
Packaging: 25mg
Price: $96.4
Updated: 2023/01/07

Cayman Chemical

Product number: 16938
Product name: Tomatidine (hydrochloride)
Purity: ≥90%
Packaging: 10mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 16938
Product name: Tomatidine (hydrochloride)
Purity: ≥90%
Packaging: 25mg
Price: $66
Updated: 2024/03/01

More

Less

Tomatidine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Tomatidine hydrochloride is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine.Tomatidine protects against muscle atrophy and boosting muscle growth (see also Ursolic Acid).

Biological Activity

Tomatidine is a steroidal alkaloid that has been found in the skins and leaves of tomatoes. It suppresses NF-κB signaling in LPS-stimulated macrophages, blocking induced expression of inducible nitric oxide synthase (iNOS) and COX-2. Tomatidine inhibits acid sphingomyelinase activity by 84.2% when used at a concentration of 10 mM. It also has antibacterial properties, preferentially blocking the replication of S. aureus variants that are pathogenic in cystic fibrosis over normal strains (MICs = 0.12 and >16 μg/ml, respectively). It prevents skeletal muscle atrophy associated with fasting or spinal cord injury in mice. Tomatidine has also been used as a negative control for cyclopamine (Item No. 11321) in studies involving signaling mediated by the hedgehog pathway.

Mode of action

Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. It activates autophagy either in mammal cells or C elegans.

Tomatidine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Tomatidine hydrochloride Suppliers

Canada 1 China 88 Germany 1 India 1 Switzerland 1 United Kingdom 3 United States 15 Global 110

Nanning Saifir Biotechnology Co., Ltd.

Tel: 18877121284
Email: 1309367106@qq.com
Country: China
ProdList: 261
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Chengdu Herbpurify Co.Ltd.

Tel: 18302802153 18981717076
Fax: 086-28-85377358
Email: 2355253619@qq.com
Country: China
ProdList: 1104
Advantage: 58

DONGSHENG CHIRAL PHARMA

Tel: 18051538752
Email: 3755454181@qq.com
Country: China
ProdList: 434
Advantage: 55

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

More

Less

View Lastest Price from Tomatidine hydrochloride manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Tomatidine hydrochloride 6192-62-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-26

Shanghai Standard Technology Co., Ltd.

Product: Tomatidine hydrochloride 6192-62-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-26

Career Henan Chemical Co

Product: TOMATIDINE HYDROCHLORIDE 6192-62-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,50kg
Release date: 2020-01-18

6192-62-7, Tomatidine hydrochlorideRelated Search:

Xanthiside Lycopene Apo-12'-lycopenal L-Hyoscyamine menisdaurin daurisoline TOMATINE TOMATIDINE OCTADECYLAMINE HYDROCHLORIDE 2-Propylpiperidine hydrochloride Cyclopentamine 2-PIPERIDINOL Dihydrocholesterol 2-AMINONONADECANE Tomatidine hydrochloride 3-PIPERIDIN-2-YL-PROPAN-1-OL cyclopentamine hydrochloride DIISOBUTYLAMINE HYDROCHLORIDE

3BETA-HYDROXY-5ALPHA-TOMATIDANE HYDROCHLORIDE

5ALPHA-TOMATIDAN-3BETA-OL HYDROCHLORIDE

TOMATIDINE HCL

TOMATIDINE HYDROCHLORIDE

SPIRPSOLAN-3-OL-(3B,5A,22B,25C) HCL

(3beta,5alpha,22beta,25S)-Spirosolan-3-ol hydrochloride

TOMATIDINE HCL(RG)

Tomatidine, Hydrochloride, >85%

ToMatidin Hydrochloride, >85%

3β-Hydroxy-5α-tomatidane hydrochloride, 5α-Tomatidan-3β-ol hydrochloride

(3β,5α,22β,25S)-Spirosolan-3-ol Hydrochloride

(3beta,5alpha,22beta,25S)-Spirosolan-3-ol hydrochloride (1:1)

3β-Hydroxy-5α-tomatidane hydrochloride

5α-Tomatidan-3β-ol hydrochloride

Tomatidine, HCl - CAS 6192-62-7 - Calbiochem

Tomatidine Hydrochloride, &gt

5alpha-Tomatidan-3beta-ol HCl

Tomatidine hydrochloride-RM

6192-62-7

C27H46ClNO2

C27H45NO2HCl

Lipid signaling

Intermediates & Fine Chemicals

Pharmaceuticals

Steroids