[Hydroxy(tosyloxy)iodo]benzene

Product Name: [Hydroxy(tosyloxy)iodo]benzene
CAS No.: 27126-76-7
Chemical Name: [Hydroxy(tosyloxy)iodo]benzene
Synonyms: HTIB;HYDROXY(TOSYLOXY)IODOBENZENE;Koser Reagent;[hydroxy(phenyl)-λ3-iodanyl] 4-methylbenzenesulfonate;NSC 294176;AKOS 91494;Koser's Regent;[Hydroxy(tosyL;KOSER'S REAGENT;KOSER'S REAGENT
CBNumber: CB6778895
Molecular Formula: C13H13IO4S
Formula Weight: 392.21
MOL File: 27126-76-7.mol

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[Hydroxy(tosyloxy)iodo]benzene Property

Melting point:: 131-137 °C (lit.)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
form: Crystalline Powder
pka: 7.59±0.58(Predicted)
color: Pale yellow
Sensitive: Light Sensitive
Merck: 14,5321
BRN: 2150074
InChIKey: LRIUKPUCKCECPT-UHFFFAOYSA-N
CAS DataBase Reference: 27126-76-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26-36
WGK Germany: 3
F: 8
HazardClass: IRRITANT
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 301035
Product name: [Hydroxy(tosyloxy)iodo]benzene
Purity: 96%
Packaging: 5g
Price: $33.84
Updated: 2024/03/01

Sigma-Aldrich

Product number: 301035
Product name: [Hydroxy(tosyloxy)iodo]benzene
Purity: 96%
Packaging: 25g
Price: $162
Updated: 2024/03/01

TCI Chemical

Product number: P1015
Product name: [Hydroxy(tosyloxy)iodo]benzene
Purity: >97.0%(T)
Packaging: 5g
Price: $92
Updated: 2024/03/01

TCI Chemical

Product number: P1015
Product name: [Hydroxy(tosyloxy)iodo]benzene
Purity: >97.0%(T)
Packaging: 25g
Price: $375
Updated: 2024/03/01

Alfa Aesar

Product number: L15701
Product name: Hydroxy(tosyloxy)iodobenzene, 97%
Packaging: 5g
Price: $37.65
Updated: 2024/03/01

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[Hydroxy(tosyloxy)iodo]benzene Chemical Properties,Usage,Production

Chemical Properties

Pale yellow crystalline powder

Uses

Reactant for:

Ligand-free palladium-catalyzed Heck-type coupling reactions
Preparation of carbodiimides via dehydrosulfurization of thioureas
Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines
Preparation of substituted anilines via aromatic aldoxime reaction
Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols
Preparation of isoxazoline N-Oxides from ?-hydroxyketoximes via oxidative N-O coupling
Ring expansion in synthesis of aminopeptidase inhibitors
Oxidation and protonation reactions in acidic conditions

Uses

Versatile synthetic reagent in phenyliodination and/or tosylation of a range of organic substrates; in oxidative transformations including oxidative rearrangements.

Purification Methods

Possible impurities are tosic acid (removed by washing with Me2CO) and acetic acid (removed by washing with Et2O). It is purified by dissolving in the minimum volume of MeOH, adding Et2O to cloud point and setting aside for the prisms to separate [Koser & Wettach J Org Chem 42 1476 1977, NMR: Koser et al. J Org Chem 41 3609 1976]. It has also been crystallised from CH2Cl2 (needles, m 140-142o) [Neiland & Karele J Org Chem, USSR (Engl Transl) 6 889 1970].

[Hydroxy(tosyloxy)iodo]benzene Preparation Products And Raw materials

Raw materials

Preparation Products

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[Hydroxy(tosyloxy)iodo]benzene Suppliers

Americas 1 Belgium 2 China 178 Europe 3 France 1 Germany 6 India 9 Japan 1 Poland 1 Switzerland 2 United Kingdom 9 United States 25 Global 238

Tokyo Chemical Industry UK Ltd.

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CARBONE SCIENTIFIC CO.,LTD

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UK GREEN SCIENTIFIC CO.,LIMITED

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VWR International

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View Lastest Price from [Hydroxy(tosyloxy)iodo]benzene manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: [Hydroxy(tosyloxy)iodo]benzene 27126-76-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-16

hebei hongtan Biotechnology Co., Ltd

Product: [Hydroxy(tosyloxy)iodo]benzene 27126-76-7
Price: US $30.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-05-14

Zhuozhou Wenxi import and Export Co., Ltd

Product: Hydroxy(tosyloxy)iodobenzene 27126-76-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

27126-76-7, [Hydroxy(tosyloxy)iodo]benzeneRelated Search:

Butylated Hydroxytoluene Benzene Ethylbenzene Tosyl chloride Tosyl cyanide Allylbenzene p-Toluenesulfonamide Fipronil CHLOROPHOSPHONAZO III TOLBUTAMIDE Iodosobenzene 2-(4-Aminopentyl(ethyl)amino)ethanol HYDROXY ITRACONAZOLE Hydroxyacetic Acid Hydrazide Iodobenzene [Hydroxy(tosyloxy)iodo]benzene [HYDROXY(METHANESULFONYLOXY)IODO]BENZENE 1-[[(4-METHYLPHENYL)SULPHONYL]OXY]-1,2-BENZIODOXOL-3(1H)-ONE

Iodine,hydroxy(4-Methylbenzenesulfonato-kO)phenyl-

[Hydroxy(tosyloxy)iodo]benzene 96%

[Hydroxy(4-toluenesulfonato)iodo]benzene

Hydroxy(phenyl)iodo tosylate

[Hydroxy(tosyloxy)iodo]benzene≥ 98%(Titration)

Hydroxy{[(4-methylphenyl)sulfonyl]oxy} phenyliodine

Koser's Regent ,HTIB

Hydroxyl(toluenesulfonyloxygengeneration)iodobenzene

NSC 294176

Phenyliodosyl hydroxide tosylate

[hydroxy(phenyl)-λ3-iodanyl] 4-methylbenzenesulfonate

HYDROXY(4-METHYLBENZENESULFONATO-O)PHENYLIODINE

IODOSOBENZENE-I-MONO-P-TOLUENESULFONATE

IODOSOBENZENE-L-MONO-4-TOLUENESULFONATE

KOSER'S REAGENT

LABOTEST-BB LT00453060

AKOS 91494

HTIB~Iodosobenzene-I-mono-p-toluenesulphonate~Kosers

Iodosobenzene-I-mono-p-toluenesulfonate, Koser's Reagent

Hydroxy(tosyloxy)iodobenzene,97%

Koser's Regent

Hydroxy{[(4-methylphenyl)sulfonyl]oxy}phenyliodine (HTIB)

Hydroxy(4-methylbenzenesulfonato-O)phenyliodine, Iodosobenzene-I-mono-p-toluenesulfonate, Kosers reagent

4-Methylbenzenesulfonic acid hydroxyphenyliodine(III) salt

[Hydroxy(tosyL

oxy)iodo]benzene

4-Methylbenzenesulfonic acid hydroxyphenyliodo(III) ester

Hydroxytosyloxyphenyliodine(III)

Phenylhydroxy(p-tolylsulfonyloxy) iodine(III)

HTIB

Hydroxy(tosyloxy)iodo]benzene,Koser's　Reagent

HTIB [Hydroxy(tosyloxy)iodo]benzene

[Hydroxy(tosyloxy)iodo]benzene, 97+% 5GR

Phenyliodosohydroxy Tosylate Koser Reagent

Hydroxy[(p-tolylsulfonyl)oxy]iodo benzene

2-hydroxy-6-iodophenyl 4-Methylbenzenesulfonate

PHENYLIODOSOHYDROXY TOSYLATE

HYDROXY(TOSYLOXY)IODOBENZENE

Iodine, hydroxy(4-methylbenzenesulfonato-O)phenyl-

Koser Reagent

[hydroxy(phenyl)-λ<sup>3</sup>-iodanyl] 4-methylbenzenesulfonate

[Hydroxy(tosyloxy)iodo]benzene(HTIB)

4-methylbenzenesulfonic acid (2-hydroxy-6-iodophenyl) ester

[Hydroxy(tosyloxy)iodo]benzene&gt

hydroxy(phenyl)-l3-iodaneyl 4-methylbenzenesulfonate

KOSER'S REAGENT

27126-76-7

2126-76-7

C13H13IO4S

CH3C6H4SO3IOHC6H5

Hypervalent Iodine

Synthetic Reagents

Hypervalent Iodine Compounds

Oxidation

Hypervalent Iodine Compounds

Oxidation

Synthetic Organic Chemistry

Phenyls & Phenyl-Het