2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

Product Name: 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine
CAS No.: 6713-54-8
Chemical Name: 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine
Synonyms: Nsc20089;Homouric;tetratomic;homouric acid;Dipyridamole Impurity 8;2,6,8,10-Tetrahydroxy-homopurine;Pyrimido[5,4-d]Pyrimidine Impurity 1;Pyrimido[5,4-d]pyrimidine-2,4,6,8-tetrol;pyrimido[5,4-d]pyrimidine-2,4,6,8-tetraol;pyriMido[5,4-d][1,3]diazine-2,4,6,8-tetrol
CBNumber: CB6875585
Molecular Formula: C6H4N4O4
Formula Weight: 196.12
MOL File: 6713-54-8.mol

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2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Property

Density: 1.89±0.1 g/cm3(Predicted)
pka: 5.90±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T796778
Product name: 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 073607
Product name: 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine
Purity: 95+%
Packaging: 5g
Price: $55
Updated: 2021/12/16

AK Scientific

Product number: W7772
Product name: 2,4,6,8-Tetrahydroxypyrimido-[5,4-d]pyrimidine
Packaging: 100mg
Price: $39
Updated: 2021/12/16

AK Scientific

Product number: W7772
Product name: 2,4,6,8-Tetrahydroxypyrimido-[5,4-d]pyrimidine
Packaging: 1g
Price: $156
Updated: 2021/12/16

Matrix Scientific

Product number: 073607
Product name: 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine
Purity: 95+%
Packaging: 25g
Price: $180
Updated: 2021/12/16

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2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Chemical Properties,Usage,Production

Uses

2,4,6,8-Tetrahydroxy-Pyrimido(5,4-d)Pyrimidine is a pharmaceutical intermediate used in the preparation of Dipyridamole, an antiplatelet drug that is used primarily in the treatment of ischaemic heart disease and stroke. 2,4,6,8-Tetrahydroxy-Pyrimido(5,4-d)Pyrimidine is also used as a herbicide to control broadleaf weeds in wheat crops.

Synthesis

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4d)Pyrimidine is prepared by the reaction of 5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid and urea. The specific synthesis steps are as follows:
5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid was charged into a two nicked flask, Urea (7.7 g, 128.0 mmol) was added dropwise with 125 ml of NaOH solution (500 g of sodium hydroxide + 1500 g of purified water) After dripping rapidly warming to 100 ° C,Insulation for one hour; continue to stir 3h,(25 ° C), filtered to obtain a solid, add purified water 250ml, heated to 60 ° C, heat lh, and then add dilute hydrochloric acid to ΡΗ = 4, cooled to room temperature filtration, washed and dried to obtain pyrimidine [5 , 4-d] pyrimidine-2,4,6,8-tetraol (tetrahydroxy), and recrystallized (ethanol solvent) to give 10.9 g in 86.9% yield.

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Preparation Products And Raw materials

Raw materials

5-AMINOOROTIC ACID Urea

Preparation Products

2,4,6,8-TETRACHLOROPYRIMIDO[5,4-D]PYRIMIDINE 2,6-Dichloro-4,8-dipiperidinopyrimidino[5,4-d]pyrimidine

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2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Suppliers

China 102 India 5 United States 10 Global 117

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
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Country: United States
ProdList: 10194
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Tel: 025-83697070
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Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
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Country: China
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XiaoGan ShenYuan ChemPharm co,ltd

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Syntechem Co.,Ltd

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China Langchem Inc.

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Shanghai T&W Pharmaceutical Co., Ltd.

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Quzhou Juhua Friendship Co., Ltd

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Bide Pharmatech Ltd.

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Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
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View Lastest Price from 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine manufacturers

Career Henan Chemical Co

Product: 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine 6713-54-8
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

6713-54-8, 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)PyrimidineRelated Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Dipyridamole Mono-O-b-D-glucuronide Dipyridamole 2,6-Dichloro-4,8-dipiperidinopyrimidino[5,4-d]pyrimidine 2,4,6,8-TETRACHLOROPYRIMIDO[5,4-D]PYRIMIDINE 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(2,2,3,3,4,4,5,5,6,6-decadeuteriopiperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol 2,2',2'',2'''-[[4-[(2-Hydroxyethyl)aMino]-8-(1-piperidinyl)pyriMido[5,4-d]pyriMidine-2,6-diyl]dinitrilo]tetrakisethanol (DipyridaMole IMpurity) Dipyridamole Tripiperidine Dipyridamole Tri(diethanolamine) 6-Des(diethanolamino)-6-chloro Dipyridamole 4,8-dichloro-2,6-dipiperidinopyrimido[5,4-d]pyrimidine Desethanol Dipyridamole Pyrimido[5,4-d]pyrimidin-4-ol (8CI) 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

1,5-dihydropyrimido[5,4-d]pyrimidine-2,4,6,8(3H,7H)tetrone

2,6,8,10-Tetrahydroxy-homopurine

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

1H,2H,3H,4H,5H,6H,7H,8H-[1,3]DIAZINO[5,4-D]PYRIMIDINE-2,4,6,8-TETRONE

Homouric

homouric acid

1,2,3,4,5,6,7,8-Octahydropyrimido[5,4-d]pyrimidine-2,4,6,8-tetrone

Pyrimido[5,4-d]pyrimidine-2,4,6,8(1H,3H,5H,7H)-tetrone

Pyrimido[5,4-d]pyrimidine-2,4,6,8-tetrol

Nsc20089

pyriMido[5,4-d][1,3]diazine-2,4,6,8-tetrol

pyriMido[5,4-d]pyriMidine-2,4,6,8(1H,3H,5H,7H)-tetraone

pyrimido[5,4-d]pyrimidine-2,4,6,8-tetraol

1,5-dihydropyrimido[5,4-d]pyrimidine-2,4,6,8-tetrone

,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

Dipyridamole Impurity 8

Pyrimido[5,4-d]Pyrimidine Impurity 1

2,4,6,8-TETRAHYDROXYPYRIMIDO-[5,4-D]PYRIMIDIN

Pyrimido[5,4-d]pyrimidine-2,4,6,8(3H,7H)-tetrone, 1,5-dihydro-

2,4,6,8-Tetrahydroxy-pynmido[5,4-d]pynmidine

tetratomic

6713-54-8 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

2,4,6, 8-tetrahydroxy pyrimidine and [5, 4-D] pyrimidine

6713-54-8

Heterocycle-Pyrimidine series