2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine
- Product Name
- 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine
- CAS No.
- 6713-54-8
- Chemical Name
- 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine
- Synonyms
- Nsc20089;Homouric;tetratomic;homouric acid;Dipyridamole Impurity 8;2,6,8,10-Tetrahydroxy-homopurine;Pyrimido[5,4-d]Pyrimidine Impurity 1;Pyrimido[5,4-d]pyrimidine-2,4,6,8-tetrol;pyrimido[5,4-d]pyrimidine-2,4,6,8-tetraol;pyriMido[5,4-d][1,3]diazine-2,4,6,8-tetrol
- CBNumber
- CB6875585
- Molecular Formula
- C6H4N4O4
- Formula Weight
- 196.12
- MOL File
- 6713-54-8.mol
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Property
- Density
- 1.89±0.1 g/cm3(Predicted)
- pka
- 5.90±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T796778
- Product name
- 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 073607
- Product name
- 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- W7772
- Product name
- 2,4,6,8-Tetrahydroxypyrimido-[5,4-d]pyrimidine
- Packaging
- 100mg
- Price
- $39
- Updated
- 2021/12/16
- Product number
- W7772
- Product name
- 2,4,6,8-Tetrahydroxypyrimido-[5,4-d]pyrimidine
- Packaging
- 1g
- Price
- $156
- Updated
- 2021/12/16
- Product number
- 073607
- Product name
- 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine
- Purity
- 95+%
- Packaging
- 25g
- Price
- $180
- Updated
- 2021/12/16
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Chemical Properties,Usage,Production
Uses
2,4,6,8-Tetrahydroxy-Pyrimido(5,4-d)Pyrimidine is a pharmaceutical intermediate used in the preparation of Dipyridamole, an antiplatelet drug that is used primarily in the treatment of ischaemic heart disease and stroke. 2,4,6,8-Tetrahydroxy-Pyrimido(5,4-d)Pyrimidine is also used as a herbicide to control broadleaf weeds in wheat crops.
Synthesis
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4d)Pyrimidine is prepared by the reaction of 5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid and urea. The specific synthesis steps are as follows:
5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid was charged into a two nicked flask, Urea (7.7 g, 128.0 mmol) was added dropwise with 125 ml of NaOH solution (500 g of sodium hydroxide + 1500 g of purified water) After dripping rapidly warming to 100 ° C,Insulation for one hour; continue to stir 3h,(25 ° C), filtered to obtain a solid, add purified water 250ml, heated to 60 ° C, heat lh, and then add dilute hydrochloric acid to ΡΗ = 4, cooled to room temperature filtration, washed and dried to obtain pyrimidine [5 , 4-d] pyrimidine-2,4,6,8-tetraol (tetrahydroxy), and recrystallized (ethanol solvent) to give 10.9 g in 86.9% yield.
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Suppliers
View Lastest Price from 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine manufacturers
- Product
- 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine 6713-54-8
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02