ChemicalBook > CAS DataBase List > O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Product Name
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
CAS No.
4604-41-5
Chemical Name
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
Synonyms
3,3'-L-Diiodothyronine;L-3,3'-Diiodothyronine;Levothyroxine EP Imp J;3,3'-Diiodo-L-thyronine;3,3'-Diiodo-L-thyronine;Levothyroxine Impurity J;Levothyroxine EP Impurity J;3,5-Diiodo-L-tyrosinedihydrae;O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine;O-(3-Iodo-4-hydroxyphenyl)-3-iodo-L-tyrosine
CBNumber
CB6930097
Molecular Formula
C15H13I2NO4
Formula Weight
525.08
MOL File
4604-41-5.mol
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O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Property

Melting point:
178-180°C
Boiling point:
520.7±50.0 °C(Predicted)
Density 
2.095±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Aqueous Base (Slightly)
form 
Solid
pka
2.17±0.20(Predicted)
color 
Off-White to Beige
Stability:
Light Sensitive
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
719536
Product name
3,3′-Diiodo-L-thyronine (T2)
Purity
98% (CP)
Packaging
1mg
Price
$189
Updated
2024/03/01
Sigma-Aldrich
Product number
719536
Product name
3,3′-Diiodo-L-thyronine (T2)
Purity
98% (CP)
Packaging
5mg
Price
$854
Updated
2024/03/01
Cayman Chemical
Product number
16748
Product name
3,3'-Diiodo-L-thyronine
Purity
≥95%
Packaging
500μg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
16748
Product name
3,3'-Diiodo-L-thyronine
Purity
≥95%
Packaging
1mg
Price
$121
Updated
2024/03/01
Sigma-Aldrich
Product number
719536
Product name
3,3′-Diiodo-L-thyronine (T2)
Purity
98% (CP)
Packaging
10mg
Price
$1610
Updated
2024/03/01
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O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Chemical Properties,Usage,Production

Description

3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.

Chemical Properties

Off-White Powder

Uses

Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.

Definition

ChEBI: 3,3'-diiodo-L-thyronine is a 3,3'-diiodothyronine. It has a role as a human metabolite.

O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

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O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine Suppliers

Canada 1 China 111 Germany 1 India 4 United Kingdom 1 United States 19 Global 137
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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China
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021-54306202 13764082696;
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China
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XiaoGan ShenYuan ChemPharm co,ltd
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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0755 28094224
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
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+86 21 50676805
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66099280 17798518460
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(1)02557626880
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cfzhang@aikonchem.com
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China
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View Lastest Price from O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine manufacturers

Career Henan Chemical Co
Product
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine 4604-41-5
Price
US $3.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-04

4604-41-5, O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosineRelated Search:

REVERSE T3 L-Thyroxine 3,5-Diiodo-L-thyronine 4-(4-Hydroxyphenoxy)-3,5-diiodo-benzaldehyde 3,5-DIIODO-4'-(4-HYDROXYPHENOXY)BENZOIC ACID Thyroxine-4-hydroxy-3,5-diiodophenyl Ether DISCONTINUED Levothyroxine EP Impurity B Levothyroxine Impurity 16 N-ForMyl Thyroxine 3,5,3',5'-Tetraiodo Thyroaldehyde 3,5-Diiodo-4-(p-Methoxyphenoxy)-benzaldehyde 3-IODO-L-TYROSINE 3,3',5-TRIIODOTHYROACETIC ACID Liothyronine IMpurity E Levothyroxine impurity E 3,3',5-TRIIODOTHYROPROPIONIC ACID Levothyroxine Impurity 14 Levothyroxine O-Methyl Amine Impurity

  • O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
  • 3,5-Diiodo-L-tyrosinedihydrae
  • (S)-α-Amino-4-[(4-hydroxy-3-iodophenyl)oxy]-3-iodobenzenepropanoic acid
  • 3-Iodo-O-(4-hydroxy-3-iodophenyl)-L-tyrosine
  • O-(3-Iodo-4-hydroxyphenyl)-3-iodo-L-tyrosine
  • 3,3'-Diiodo-L-thyronine
  • (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
  • (2S)-2-amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propionic acid
  • (2S)-2-azanyl-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propanoic acid
  • 3-[4-(4-Hydroxy-3-iodophenoxy)-3-iodophenyl]-L-alanine
  • L-Tyrosine,O-(4-hydroxy-3-iodophenyl)-3-iodo-
  • 3,3'-L-Diiodothyronine
  • Levothyroxine EP Impurity J
  • L-3,3'-Diiodothyronine
  • Levothyroxine Impurity 9（Levothyroxine EP Impurity J）
  • 3,3'-L-Diiodothyronine (Levothyroxine Impurity J)
  • Levothyroxine Impurity J
  • Levothyroxine EP Imp J
  • 3'-L-Diiodothyronine (Levothyroxine Impurity J)
  • O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine USP/EP/BP
  • Alanine,3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]-, L- (8CI)
  • 3,3'-Diiodo-L-thyronine (Levothyroxine Impurity)
  • 3,3'-Diiodo-L-thyronine
  • 4604-41-5
  • Amino Acids & Derivatives
  • Labeling and Diagnostics Reagents