ChemicalBook > CAS DataBase List > 2,4,5-Triamino-6-chloropyrimidine

2,4,5-Triamino-6-chloropyrimidine

Product Name
2,4,5-Triamino-6-chloropyrimidine
CAS No.
1194-78-1
Chemical Name
2,4,5-Triamino-6-chloropyrimidine
Synonyms
2,4,5-Triamino-6-chloropyrimid;2,4,5-Triamio-6-chloropyrimidine;6-ChloropyriMidine-2,4,5-triaMine;6-Chloro-2,4,5-pyrimidinetriamine;2,4,5-Triamino-6-chloropyrimidine;2,4,5-Pyrimidinetriamine, 6-chloro-;2,4,5-Triamino-6-hydroxypyrimidine dihydrochloride
CBNumber
CB6946885
Molecular Formula
C4H6ClN5
Formula Weight
159.58
MOL File
1194-78-1.mol
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2,4,5-Triamino-6-chloropyrimidine Property

storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H311Toxic in contact with skin

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

AK Scientific
Product number
3339AA
Product name
6-Chloropyrimidine-2,4,5-triamine
Packaging
1g
Price
$296
Updated
2021/12/16
AK Scientific
Product number
3339AA
Product name
6-Chloropyrimidine-2,4,5-triamine
Packaging
250mg
Price
$149
Updated
2021/12/16
Alichem
Product number
1194781
Product name
6-Chloropyrimidine-2,4,5-triamine
Packaging
1g
Price
$185.64
Updated
2021/12/16
Chemenu
Product number
CM167418
Product name
6-chloropyrimidine-2,4,5-triamine
Purity
97%
Packaging
1g
Price
$186
Updated
2021/12/16
Chemenu
Product number
CM167418
Product name
6-chloropyrimidine-2,4,5-triamine
Purity
97%
Packaging
5g
Price
$681
Updated
2021/12/16
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2,4,5-Triamino-6-chloropyrimidine Chemical Properties,Usage,Production

Synthesis

55583-59-0

1194-78-1

General procedure for the synthesis of 2,4,5-triamino-6-chloropyrimidine from 2,5-diamino-4,6-dichloropyrimidine: 2,5-diamino-4,6-dichloropyrimidine (1 equiv.) was suspended in concentrated ammonia (18 mL/mmol), placed in a sealed reaction tube, and heated to 135 °C for 24 hours. Upon completion of the reaction, the reaction mixture was concentrated under vacuum and subsequently purified by silica gel column chromatography with the eluent being a solvent mixture of dichloromethane/methanol/concentrated ammonia to give the final target compound 2,4,5-triamino-6-chloropyrimidine (93% yield). The structure of the product was confirmed by 13C NMR (101 MHz, J6-DMSO) with the chemical shifts of δ 156.0, 155.5, 113.3, 39.5, respectively; the analytical results of high-resolution mass spectrometry (HRMS-ESI) were in accordance with the theoretical values, with the calculated value of C4H7ClN5 [M + H]+ 160.03845 and the measured value of 160.0385.

References

[1] Patent: WO2016/87665, 2016, A2. Location in patent: Page/Page column 102

2,4,5-Triamino-6-chloropyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

6-Chloroguanine
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2,4,5-Triamino-6-chloropyrimidine Suppliers

China 38 Germany 1 India 1 Slovakia 1 United Kingdom 2 United States 9 Global 52
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
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View Lastest Price from 2,4,5-Triamino-6-chloropyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,4,5-TriaMino-6-chloropyriMidine 1194-78-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-15
Career Henan Chemical Co
Product
6-Chloropyrimidine-2,4,5-triamine 1194-78-1
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-28

1194-78-1, 2,4,5-Triamino-6-chloropyrimidineRelated Search:

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  • 2,4,5-Triamino-6-chloropyrimid
  • 2,4,5-Triamino-6-chloropyrimidine
  • 6-Chloro-2,4,5-pyrimidinetriamine
  • 6-ChloropyriMidine-2,4,5-triaMine
  • 2,4,5-Triamino-6-hydroxypyrimidine dihydrochloride
  • 2,4,5-Pyrimidinetriamine, 6-chloro-
  • 2,4,5-Triamio-6-chloropyrimidine
  • 1194-78-1
  • 51324-78-1
  • FINE Chemical & INTERMEDIATES