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Zilpaterol hydrochloride

Product Name
Zilpaterol hydrochloride
CAS No.
119520-06-8
Chemical Name
Zilpaterol hydrochloride
Synonyms
Zilpaterol Hcl;paterol hydrochloride;Zipatero hydrochloride;ilpaterol hydrochloride;Zilpaterol hydrochloride;GIEFXLLRTJNFGT-JZKFLRDJSA-N;Zilpaterol hydrochloride (relstereo);Zilpaterol hydrochloride in Methanol;Zilpaterol hydrochloride/Zilpaterol Hcl;Zilpaterol hydrochloride 100 μg/ml Water
CBNumber
CB6966230
Molecular Formula
C14H20ClN3O2
Formula Weight
297.78
MOL File
119520-06-8.mol
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Zilpaterol hydrochloride Property

storage temp. 
2-8°C
solubility 
DMF: 0.1 mg/ml,DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
InChI
InChI=1/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19;/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19);1H/t11-,13-;/s3
InChIKey
GIEFXLLRTJNFGT-WLBMKERDNA-N
SMILES
O[C@@H]1[C@H](CCN2C(=O)NC3C=CC=C1C2=3)NC(C)C.Cl |&1:1,2,r|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32379
Product name
Zilpaterol hydrochloride
Purity
VETRANAL
Packaging
10mg
Price
$1000
Updated
2025/07/31
Cayman Chemical
Product number
16484
Product name
Zilpaterol (hydrochloride)
Purity
≥95%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
16484
Product name
Zilpaterol (hydrochloride)
Purity
≥95%
Packaging
5mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
16484
Product name
Zilpaterol (hydrochloride)
Purity
≥95%
Packaging
10mg
Price
$341
Updated
2024/03/01
Adipogen Life Sciences
Product number
CDX-Z0025-M010
Product name
Zilpaterol hydrochloride
Purity
≥97%(HPLC)
Packaging
10mg
Price
$447
Updated
2021/12/16
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Zilpaterol hydrochloride Chemical Properties,Usage,Production

Description

Zilpaterol is a β-adrenergic receptor agonist that putatively through activation of protein kinase A increases protein synthesis in skeletal muscle fibers, as well as reduces lipogenesis and increases lipolysis in adipose tissues. It was approved by the FDA in 2006 as a veterinary food additive for the purpose of increasing lean body weight and improving feed efficiency in commercial beef cattle.

Definition

Zilpaterol hydrochloride, (±)-trans-4,5,6,7-tetrahydro-7-hydroxy-6-(isopropylamino) imidazo[4,5,1-jk]-[1]benzazepin-2(1H)-one hydrochloride; (zilpaterol HCl; CAS No. 119520- 06-8), is a β2-adrenoreceptor agonist repartitioning agent (FAO, 2013). It is used to increase rate of body weight gain, improve feed efficiency and increase carcass muscle ratio in cattle fed in confinement before slaughter . There are four enantiomers of zilpaterol HCl. The product in use is racemic trans-zilpaterol HCl, a mixture of the (6R,7R) and (6S,7S) enantiomers.

Materials Uses

Zilpaterol hydrochloride is marketed as a compound that will increase rate of BW gain, improve feed efficiency, and increase carcass leanness in cattle fed in confinement systems. Zilpaterol hydrochloride has also been shown to increase weight of gross primal and boneless closely trimmed primals, and boneless closely trimmed retail cuts as a percentage of carcass weight, when carcass weights were held constant (Plascencia et al., 1999). Additionally, slaughtering a lot of cattle on the same date can be problematic and may require longer than expected withdrawal periods and may result in withdrawal periods in excess of 3 d.

Solubility in organics

Zilpaterol hydrochloride is very soluble in water and in other aqueous media (about 50% of product dissolved) at different pH values (1–10). It is only slightly soluble in methanol (about 3%) and practically insoluble in most organic solvents (<0.1%) such as ethanol, acetone, ethyl-acetate, isopropyl ether, hexane, toluene, chloroform, dichloromethane or n-octanol.

References

[1] L AVENDA?O-REYES. Effects of two beta-adrenergic agonists on finishing performance, carcass characteristics, and meat quality of feedlot steers.[J]. Journal of animal science, 2006, 84 12: 3259-3265. DOI: 10.2527/jas.2006-173
[2] E K MILLER. Zilpaterol hydrochloride alters abundance of β-adrenergic receptors in bovine muscle cells but has little effect on de novo fatty acid biosynthesis in bovine subcutaneous adipose tissue explants.[J]. Journal of animal science, 2012, 90 4: 1317-1327. DOI: 10.2527/jas.2011-4589
[3] R J DELMORE  B J J  J M Hodgen. Perspectives on the application of zilpaterol hydrochloride in the United States beef industry.[J]. Journal of animal science, 2010, 88 8: 2825-2828. DOI: 10.2527/jas.2009-2473

Zilpaterol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Zilpaterol hydrochloride manufacturers

Hebei Zhanyao Biotechnology Co. Ltd
Product
Zilpaterol hydrochloride 119520-06-8
Price
US $10.00/Kg/Bag
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-10
Hebei Runbin Biotechnology Co. LTD
Product
Zilpaterol hydrochloride 119520-06-8
Price
US $1000.00/KG
Min. Order
1KG
Purity
99.9%
Supply Ability
20tons
Release date
2020-09-10
Masteam Bio-tech Co., Ltd.
Product
Zilpaterol hydrochloride 119520-06-8
Price
US $430.00/KG
Min. Order
1KG
Purity
99% HPLC
Supply Ability
10000kg
Release date
2020-06-30

119520-06-8, Zilpaterol hydrochlorideRelated Search:


  • Zilpaterol Hcl
  • IMidazo[4,5,1-jk][1]benzazepin-2(1H)-one,4,5,6,7-tetrahydro-7-hydroxy-6-[(1-Methylethyl)aMino]-, hydrochloride (1:1),(6R,7R)-rel-
  • (6RS,7RS)-4,5,6, 7-Tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[ 4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride
  • Zilpaterol hydrochloride (relstereo)
  • GIEFXLLRTJNFGT-JZKFLRDJSA-N
  • ilpaterol hydrochloride
  • (+/1)-trans-4,5,6,7-Tetrahydro-7-hydroxy-6-(isopropylamino)imidazo[4,5,1-jk]-[1]benzazepin-2(1H)-one hydrochloride
  • Zilpaterol hydrochloride
  • paterol hydrochloride
  • Zipatero hydrochloride
  • Zilpaterol hydrochloride/Zilpaterol Hcl
  • Zilpaterol hydrochloride in Methanol
  • Zilpaterol hydrochloride 100 μg/ml Water
  • 119520-06-8
  • C14H19N3O2HCl