Rutaecarpine

Product Name: Rutaecarpine
CAS No.: 20575-76-2
Chemical Name: Rutaecarpine
Synonyms: Ai3-51108;Nsc 255317;Brn 2116874;Rutaecarpine;3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA);1,1'-Hexamethylenebis[3,3-dimethylurea];Urea, 1,1'-hexamethylenebis(3,3-dimethyl-;1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea);N,N''-1,6-Hexanediylbis[N',N'-dimethylurea];1,1'-(Hexane-1,6-diyl)bis(3,3-dimethylurea)
CBNumber: CB6975933
Molecular Formula: C12H26N4O2
Formula Weight: 258.36
MOL File: 20575-76-2.mol

More

Less

Rutaecarpine Property

Boiling point:: 512.3±33.0 °C(Predicted)
Density: 1.021±0.06 g/cm3(Predicted)
pka: 13.98±0.46(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S590355
Product name: 3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA)
Purity: Aldrich
Packaging: 250mg
Price: $29.8
Updated: 2024/03/01

More

Less

Rutaecarpine Chemical Properties,Usage,Production

Biological Functions

Rutaecarpine also inhibits accumulation of macrophages and cholesterol in atherosclerotic lesions and increases cholesterol excretion in other animal models. Additionally, rutaecarpine inhibits hypoxia-induced production of ROS and lactate dehydrogenase and suppresses apoptosis in myocardiocytes. In other cellular models, rutaecarpine decreases corticosterone production, potentially through inhibition of cAMP, 3β-hydroxysteroid dehydrogenase, and 11β-hydroxylase activity.

Biological Activity

Rutaecarpine is an indoloquinazoline alkaloid originally found in Evodia; it exhibits anti-inflammatory, anti-atherosclerotic, cardioprotective, anorexigenic, and anti-obesity activities. Rutaecarpine inhibits COX-2 and also decreases food intake, weight gain, and serum glucose, leptin, and insulin levels in vivo by inhibiting expression of neuropeptide Y and AgRP.

Mechanism of action

Rutaecarpine also inhibits production of ROS, NO, and iNOS, potentially through inhibition of NADPH oxidase. In macrophages, rutaecarpine inhibits arachidonic acid release and decreases production of prostaglandin E2 (PGE2); in other in vitro models, it inhibits collagen-stimulated formation of thromboxane B2 and inosine monophosphate.

Rutaecarpine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Rutaecarpine Suppliers

China 37 Germany 1 India 1 United States 5 Global 44

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

Wonda Science

Tel: --
Fax: --
Email: wonda@wondascience.com
Country: United States
ProdList: 2192
Advantage: 50

Ivy Fine Chemicals

Tel: --
Fax: --
Email: sales@ivychem.com
Country: United States
ProdList: 6493
Advantage: 58

More

Less

View Lastest Price from Rutaecarpine manufacturers

Career Henan Chemical Co

Product: Rutaecarpine 20575-76-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons
Release date: 2020-02-03

20575-76-2, RutaecarpineRelated Search:

HexanitrodiphenylaMine 1,3-Dimethylurea Methylcyclohexane Cyclohexane Evodiamine (Hydroxymethyl)urea Hexane Explosion regulator 14-Fomyldihydroxyrutaecarpine Rutaecarpine std.,Rutaecarpine RUTAECARPINE(SH) RUTAECARPINE(RG) DEHYDROEVODIAMINE HYDROCHLORIDE Rutaecarpine

3-[6-(dimethylcarbamoylamino)hexyl]-1,1-dimethyl-urea

1,1'-Hexamethylenebis[3,3-dimethylurea]

N,N''-1,6-Hexanediylbis[N',N'-dimethylurea]

Rutaecarpine

Ai3-51108

Brn 2116874

Nsc 255317

Urea, 1,1'-hexamethylenebis(3,3-dimethyl-

Urea, N,N''-1,6-hexanediylbis(N',N'-dimethyl- (9ci)

3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA)

1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea)

Urea, N,N''-1,6-hexanediylbis[N',N'-dimethyl-

1,1'-(Hexane-1,6-diyl)bis(3,3-dimethylurea)

20575-76-2

82-26-4