ChemicalBook > CAS DataBase List > N-Desmethyl Tamoxifen Hydrochloride

N-Desmethyl Tamoxifen Hydrochloride

Product Name
N-Desmethyl Tamoxifen Hydrochloride
CAS No.
15917-65-4
Chemical Name
N-Desmethyl Tamoxifen Hydrochloride
Synonyms
Nsc372964;Tamoxifen EP Impurity F HCl; N-Demethyltamoxifen Hydrochlorid;2-[4-[(Z)-1,2-Diphenylbut-1-enyl]ph;Tamoxifen Citrate EP Impurity F HCl;Tamoxifen Citrate Impurity F as Hydrochloride;Tamoxifen Citrate EP Impurity F as Hydrochloride;(Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine;Tamoxifen Citrate Impurity 6(Tamoxifen Citrate EP Impurity F);Tamoxifen Citrate Impurity 6(Tamoxifen Citrate EP Impurity F HCl)
CBNumber
CB71176581
Molecular Formula
C25H27NO.ClH
Formula Weight
393.955
MOL File
15917-65-4.mol
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N-Desmethyl Tamoxifen Hydrochloride Property

Melting point:
225-227°C
storage temp. 
room temp
solubility 
DMSO: ≥20mg/mL
form 
solid
color 
White to off-white
Stability:
Light sensitive
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Safety

Hazard Codes 
T,N
Risk Statements 
45-46-60-50/53
Safety Statements 
53-45-60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H350May cause cancer

H360May damage fertility or the unborn child

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D9069
Product name
N-Desmethyltamoxifen HCl
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$281
Updated
2024/03/01
TRC
Product number
D293900
Product name
N-DesmethylTamoxifenHydrochloride
Packaging
50mg
Price
$1390
Updated
2021/12/16
ChemScene
Product number
CS-0112190
Product name
N-Desmethyltamoxifenhydrochloride
Purity
99.62%
Packaging
100mg
Price
$1650
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
9028
Product name
N-Desmethyltamoxifen HCl
Packaging
25mg
Price
$1960
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000705
Product name
N-DESMETHYL TAMOXIFEN HYDROCHLORIDE
Purity
95.00%
Packaging
50MG
Price
$1986.3
Updated
2021/12/16
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N-Desmethyl Tamoxifen Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

A main metabolite of the anti-cancer drug Tamoxifen (T006000).

Uses

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

Biochem/physiol Actions

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

N-Desmethyl Tamoxifen Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Desmethyl Tamoxifen Hydrochloride Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
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65
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1955
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55
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9649
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Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
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51456
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80
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
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Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
4553
Advantage
55

15917-65-4, N-Desmethyl Tamoxifen HydrochlorideRelated Search:


  • N-Demethyltamoxifen Hydrochlorid
  • (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride
  • Nsc372964
  • 2-[4-[(1Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N-methylethanamine hydrochloride
  • (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine
  • Tamoxifen Citrate EP Impurity F HCl
  • 2-[4-[(Z)-1,2-Diphenylbut-1-enyl]ph
  • Tamoxifen EP Impurity F HCl
  • Tamoxifen Citrate Impurity 6(Tamoxifen Citrate EP Impurity F HCl)
  • Tamoxifen Citrate Impurity 6(Tamoxifen Citrate EP Impurity F)
  • (Z)-2-(4-(1,2-Diphenylbut-1-en-1-yl)phenoxy)-N-methylethanamine hydrochloride
  • 2-[4-[(Z)-1,2-Diphenylbut-1-enyl]phenoxy]-N-methylethanamine Hydrochloride
  • PKC,sphingosine,inhibit,N-Desmethyltamoxifen,NDesmethyltamoxifen hydrochloride,cells,Protein kinase C,Inhibitor,phosphorylation,metabolism,Estrogen Receptor/ERR,carcinoma,AML,Drug Metabolite,ceramide,N Desmethyltamoxifen hydrochloride,Endogenous Metabolite,metabolite,antiestrogen
  • Tamoxifen Citrate EP Impurity F as Hydrochloride
  • Tamoxifen Citrate Impurity F as Hydrochloride
  • 15917-65-4
  • C25H28ClNO
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Various Metabolites and Impurities