6-Chloropyrazine-2-carboxylic acid
- Product Name
- 6-Chloropyrazine-2-carboxylic acid
- CAS No.
- 23688-89-3
- Chemical Name
- 6-Chloropyrazine-2-carboxylic acid
- Synonyms
- C90116;6-Chloro-pyrazine-2-acid;2-Chloro-6-carboxypyrazine;2-Carboxy-6-chloropyrazine;6-Chloropyrazine-2-carbox...;2-Chloro-6-pyrazinecarboxylicacid;6-Chloropyrazine-2-carboxylic acid;6-Chloropyrazine-2-carboxylicAcid>2-Pyrazinecarboxylic acid, 6-chloro-;6-Chloropyrazine-2-carboxylicacid,95%
- CBNumber
- CB71180168
- Molecular Formula
- C5H3ClN2O2
- Formula Weight
- 158.54
- MOL File
- 23688-89-3.mol
6-Chloropyrazine-2-carboxylic acid Property
- Melting point:
- 158-160 °C
- Boiling point:
- 323.6±37.0 °C(Predicted)
- Density
- 1.579±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 2.54±0.10(Predicted)
- form
- Solid
- color
- Light yellow to Brown
- InChI
- InChI=1S/C5H3ClN2O2/c6-4-2-7-1-3(8-4)5(9)10/h1-2H,(H,9,10)
- InChIKey
- KGGYMBKTQCLOTE-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=NC(Cl)=CN=C1
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C2725
- Product name
- 6-Chloropyrazine-2-carboxylic Acid
- Purity
- >96.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $99
- Updated
- 2025/07/31
- Product number
- C2725
- Product name
- 6-Chloropyrazine-2-carboxylic Acid
- Purity
- >96.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $395
- Updated
- 2025/07/31
- Product number
- C350970
- Product name
- 6-Chloropyrazine-2-carboxylic Acid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C350970
- Product name
- 6-Chloropyrazine-2-carboxylic Acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FC07732
- Product name
- 6-Chloropyrazine-2-carboxylic acid
- Packaging
- 25g
- Price
- $425
- Updated
- 2021/12/16
6-Chloropyrazine-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
23611-75-8
23688-89-3
General procedure for the synthesis of 6-chloropyrazine-2-carboxylic acid from methyl 6-chloropyrazine-2-carboxylate: 6-chloropyrazine-2-carboxylic acid methyl ester (1.78 g, 10.3 mmol) was dissolved in ethanol (25 mL). 1 M sodium hydroxide solution (25 mL) was added and the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the mixture was acidified to pH 3 with 1 M aqueous hydrochloric acid solution. subsequently, the reaction mixture was diluted with water (150 mL) and extracted with ethyl acetate (4 × 100 mL). The organic phases were combined, washed with saturated saline (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the title compound 6-chloropyrazine-2-carboxylic acid as a white solid (1.54 g, 94% yield). Mass spectrum (DCI/NH3) m/z 176 (M + NH4)+.
References
[1] Patent: US2009/281118, 2009, A1. Location in patent: Page/Page column 14
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 21, p. 7678 - 7692
6-Chloropyrazine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Chloropyrazine-2-carboxylic acid manufacturers
- Product
- 6-Chloropyrazine-2-carboxylic acid 23688-89-3
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
- Product
- 6-Chloropyrazine-2-carboxylic acid 23688-89-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 6-Chloropyrazine-2-carboxylic acid 23688-89-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09