ChemicalBook > CAS DataBase List > Esomeprazole potassium

Esomeprazole potassium

Product Name: Esomeprazole potassium
CAS No.: 161796-84-5
Chemical Name: Esomeprazole potassium
Synonyms: Esomeprazole potassium;(S)-Omeprazole potassium;Esomeprazole potassium USP/EP/BP;Esomeprazole Impurity 46 Potassium Salt;(S)-5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d];potassium,5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide;(R)-5-METHOXY-2-((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYLSULFINYL)BENZO[D]IMIDAZOL-1-IDE POTASSIUM SALT;6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole potassium salt (1:1);1H-Benzimidazole,6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-,potassium salt (1:1)
CBNumber: CB71229920
Molecular Formula: C17H20KN3O3S
Formula Weight: 385.52
MOL File: 161796-84-5.mol

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Esomeprazole potassium Property

vapor pressure: 0Pa at 25℃
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0002606
Product name: ESOMEPRAZOLE POTASSIUM
Purity: 95.00%
Packaging: 25MG
Price: $626.15
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002606
Product name: ESOMEPRAZOLE POTASSIUM
Purity: 95.00%
Packaging: 100MG
Price: $771.79
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002606
Product name: ESOMEPRAZOLE POTASSIUM
Purity: 95.00%
Packaging: 500MG
Price: $1466.09
Updated: 2021/12/16

DC Chemicals

Product number: DC24176
Product name: Esomeprazolepotassiumsalt
Purity: >98%
Packaging: 1g
Price: $800
Updated: 2021/12/16

Crysdot

Product number: CD31003158
Product name: Esomeprazolepotassium
Purity: 98+%
Packaging: 50mg
Price: $126
Updated: 2021/12/16

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Esomeprazole potassium Chemical Properties,Usage,Production

Uses

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole potassium salt has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].

in vivo

Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis^[2].

Animal Model:	C57BL/6J mice (8-weeks old, 25-30 g) treated with cotton smoke-induced lung injury^[2]
Dosage:	30 mg/kg, 300 mg/kg
Administration:	Oral gavage; daily; for 19 or 11 days
Result:	Significantly inhibited the progression of fibrosis throughout the lungs of the animals.

References

[1] Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46. DOI:10.18433/j34608
[2] Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16. DOI:10.3389/fphar.2017.00016
[3] Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9. DOI:10.1093/ajhp/59.14.1333

Esomeprazole potassium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Esomeprazole potassium manufacturers

Career Henan Chemica Co

Product: Esomeprazole potassium 161796-84-5
Price: US $1.00/g
Min. Order: 1g
Purity: 85.0-99.8%
Supply Ability: 20ton
Release date: 2020-10-29

Dideu Industries Group Limited

Product: Esomeprazole potassium 161796-84-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-17

161796-84-5, Esomeprazole potassiumRelated Search:

Dimethyl sulfoxide 2,5-Dimethylpyridine Potassium sorbate Anisole (Trifluoromethoxy)benzene ETHANE Dimethyl ether Potassium Acetate Dacthal Benzimidazole Potassium iodide Potassium bromate Dimethyl carbonate Dimethyl sulfate Potassium Citrate Dimethyl sulfide Dimethyl fumarate Esomeprazole

(S)-Omeprazole potassium

6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole potassium salt (1:1)

(R)-5-METHOXY-2-((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYLSULFINYL)BENZO[D]IMIDAZOL-1-IDE POTASSIUM SALT

Esomeprazole potassium

(S)-5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]

potassium,5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide

1H-Benzimidazole,6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-,potassium salt (1:1)

Esomeprazole potassium USP/EP/BP

Esomeprazole Impurity 46 Potassium Salt

161796-84-5