ChemicalBook > CAS DataBase List > BANISTERINE MONOHYDRATE

BANISTERINE MONOHYDRATE

Product Name: BANISTERINE MONOHYDRATE
CAS No.: 442-51-3
Chemical Name: BANISTERINE MONOHYDRATE
Synonyms: Harmin;Garmin;Yagein;Harmine;Yageine;Yajeine;Hal base;Telepathin;Harmine>Telepathien
CBNumber: CB7123131
Molecular Formula: C13H12N2O
Formula Weight: 212.25
MOL File: 442-51-3.mol

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BANISTERINE MONOHYDRATE Property

Melting point:: 262-264 °C(lit.)
Boiling point:: 352.09°C (rough estimate)
Density: 1.1128 (rough estimate)
refractive index: 1.6920 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Solubility Slightly soluble in water, ethanol, ether, chloroform
pka: 7.7(at 25℃)
form: Crystalline Powder
color: White to off-white
PH Range: Blue 0 uorescence (7.2) to yellow 0 uorescence (8.9)
Water Solubility: Soluble in DMSO (100 mM), DMF (~1.5 mg/ml), ethanol (~1.5 mg/ml), and PBS (pH 7.2, ~0.25 mg/ml). Insoluble in water.
λmax: 241nm, 301nm, 336nm
Merck: 14,4616
BRN: 178813
Major Application: Inks, antitumor agents, inhibition of cell proliferation, blocking breast and prostate cancer cells, tracer for ductal pancreatic cancer, DNA binding properties, treatment of neoplasia, antioxidants, therapy of depression, antileishmanial agent, treatment of parkinsonism, antiAIDS agents, antihypoxia agents, drugs, treatment of dependency disorder, psychiatric and neurological illness, antibiotics, antimalarial agents
InChIKey: BXNJHAXVSOCGBA-UHFFFAOYSA-N
LogP: 3.560
CAS DataBase Reference: 442-51-3(CAS DataBase Reference)
NIST Chemistry Reference: Harmine(442-51-3)

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Safety

Hazard Codes: Xn
Risk Statements: 25-36-20/21/22
Safety Statements: 22-24/25-36/37-26-36
RIDADR: 1544
WGK Germany: 3
RTECS: UV0175000
HazardClass: 6.1
PackingGroup: III
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89702
Product name: Harmine
Purity: phyproof<SUP>®</SUP> Reference Substance
Packaging: 50 mg
Price: $281
Updated: 2025/07/31

Sigma-Aldrich

Product number: 286044
Product name: Harmine
Purity: 98%
Packaging: 1g
Price: $135
Updated: 2025/07/31

TCI Chemical

Product number: H0001
Product name: Harmine
Purity: >98.0%(T)
Packaging: 1g
Price: $126
Updated: 2025/07/31

Cayman Chemical

Product number: 10010324
Product name: Harmine
Purity: ≥98%
Packaging: 250mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 10010324
Product name: Harmine
Purity: ≥98%
Packaging: 500mg
Price: $57
Updated: 2024/03/01

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BANISTERINE MONOHYDRATE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A CNS stimulant isolated from seeds of Peganum harmala L. Zygophyllaceae

Uses

antiparkinsonian, CNS stimulant

Uses

central nervous system stimulant

Definition

ChEBI: A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7.

General Description

The combination index (CI, serves as a quantitative indicator of pharmacological interactions) for harmaline/harmine and methylene blue/harmine was studied.

Biological Activity

Central nervous system stimulant.

Synthesis

486-93-1

442-51-3

General procedure for the synthesis of 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole from camptothecin standard 002: 5 mmol of 6-methoxytryptamine was placed in a 100 mL round-bottomed flask, 50 mL of an aqueous solution containing 1 mL of concentrated hydrochloric acid was added, and the reaction was stirred at 30 °C until complete dissolution. Subsequently, 10 mmol of acetaldehyde was added and the reaction was continued for 1 hour. After completion of the reaction, the pH was adjusted to 8 with aqueous sodium bicarbonate, filtered and dried to obtain 1-methyl-7-methoxy-tetrahydro-β-carboline. The dried 1-methyl-7-methoxy-tetrahydro-β-carboline was transferred to another 100 mL round-bottom flask, 50 mL of toluene and 5% Pd/C catalyst were added, and the reaction was refluxed for 24 hours. At the end of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure. Finally, it was purified by recrystallization from acetone to give 1-methyl-7-methoxy-β-carboline (3.6 mmol, 72% yield).

storage

Store at RT

Purification Methods

Crystallise harmine from MeOH and sublime it in a vacuum. See hydrochloride below. [Beilstein 23 II 348, 23 III/IV 2702, 23/12 V 237.]

References

[1] Angewandte Chemie - International Edition, 2013, vol. 52, # 27, p. 6983 - 6987
[2] Ross. Khim. Zh., 2013, vol. 125, # 27, p. 7121 - 7125,5
[3] Patent: CN104557916, 2017, B. Location in patent: Paragraph 0034-0036
[4] Chemische Berichte, 1930, vol. 63, p. 2245,2247
[5] Tetrahedron, 2002, vol. 58, # 31, p. 6185 - 6197

BANISTERINE MONOHYDRATE Preparation Products And Raw materials

Raw materials

Aluminium-nickel Hydantoin 6-Methoxyindole N,N-Dimethylformamide Potassium hydroxide Sodium sulfide Piperidine Phosphorus oxitrichloride Potassium dichromate Acetic acid Acetaldehyde Pyridine Ammonia

Preparation Products

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View Lastest Price from BANISTERINE MONOHYDRATE manufacturers

Shaanxi Xianhe Biotech Co., Ltd

Product: Harmine 442-51-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-25

Hebei Chuanghai Biotechnology Co., Ltd

Product: Harmaline 442-51-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-06

Changsha Staherb Natural Ingredients Co., Ltd.

Product: BANISTERINE MONOHYDRATE; Harmel seed extract 442-51-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: ≥98% HPLC
Supply Ability: 1000KG
Release date: 2022-09-21

442-51-3, BANISTERINE MONOHYDRATERelated Search:

VERATRIDINE daurisoline menisdaurin Xanthiside HARMALOL 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one HARMALINE L-carnitine Icariin Evodiamine Vasicine 9H-PYRIDO[3,4-B]INDOLE HARMINE HYDROCHLORIDE BANISTERINE MONOHYDRATE 9-METHOXYCANTHIN-6-ONE 7-Methoxy-b-carboline-1-propionic acid BROMOHARMINE HBR HARMINE METHYL IODIDE

Harmine

1-Methyl-7-Methoxy-β-carboline

Hal base

Harmine(Banisterine)

1-Methyl-7-methoxy-beta-carboline

4-b)indole,7-methoxy-1-methyl-9h-pyrido(

7-Methoxy-1-methyl-9H-beta-carboline

9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-

Garmin

Harmin

Leucoharmine

Harmine derivative

Ban- Bisterin

Harmine, 98%, from Peganum harmala L.

Telepathien

Telepathin

Yagein

Yageine

Yajeine

BANISTERINE MONOHYDRATE

HARMAN MONOHYDROCHLORIDE MONOHYDRATE

HARMINE MONOHYDRATE

TELEPATHINE MONOHYDRATE

HARMINE FREE BASE

Harmine,98+%

PYRIDO(3,4-B)INDOLE,7-METHOXY-1-METHYL-

7-Methoxy-1-methyl-9H-pyrido[3,4-β]indole

7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole

Harmine&gt

Harmel seed extract

Harmine ( Natural)

Harmine, DYRK1A inhibitor

Harmine, 10 mM in DMSO

Harmine solution

442-51-3

C12H10N2HClH2O

Central nervous system stimulant.

reagent

standard substance

Inhibitors

Signalling

Indole Derivatives

Intermediates & Fine Chemicals

Pharmaceuticals

Fluorescent

Heterocyclic

Heterocyclic Compounds

Alkaloids

Biochemistry

Indole Alkaloids

Neurochemicals