4-Iodopyridine
- Product Name
- 4-Iodopyridine
- CAS No.
- 15854-87-2
- Chemical Name
- 4-Iodopyridine
- Synonyms
- 4-Iodopyride;4-lodopyridine;p-iodopyridine;4-IODOPYRIDINE;BUTTPARK 96\50-18;4-pyridine iodide;4-Iodopyridine>Pyridine, 4-iodo-;4-Iodopyridine 96%;4-Iodine Pyridine
- CBNumber
- CB7124406
- Molecular Formula
- C5H4IN
- Formula Weight
- 205
- MOL File
- 15854-87-2.mol
4-Iodopyridine Property
- Melting point:
- 94-99 °C
- Boiling point:
- 212~215℃
- Density
- 1.081g/cm3
- refractive index
- 1.5290
- storage temp.
- -20°C
- solubility
- soluble in Methanol
- form
- Crystals or Powder
- pka
- pK1:4.02(＋1) (20°C)
- color
- Pale brown to dark green-brown
- Sensitive
- Light Sensitive
- BRN
- 1594
- InChI
- InChI=1S/C5H4IN/c6-5-1-3-7-4-2-5/h1-4H
- InChIKey
- RTLUPHDWSUGAOS-UHFFFAOYSA-N
- SMILES
- C1=NC=CC(I)=C1
- CAS DataBase Reference
- 15854-87-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-41-37/38-22
- Safety Statements
- 26-36-39
- WGK Germany
- 3
- Hazard Note
- Irritant/Light Sensitive
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 722170
- Product name
- 4-Iodopyridine
- Purity
- 96%
- Packaging
- 1g
- Price
- $98.44
- Updated
- 2025/07/31
- Product number
- I0673
- Product name
- 4-Iodopyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $154
- Updated
- 2025/07/31
- Product number
- I0673
- Product name
- 4-Iodopyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $457
- Updated
- 2025/07/31
- Product number
- I719430
- Product name
- 4-Iodopyridine
- Packaging
- 25g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 45661
- Product name
- 4-IODOPYRIDINE
- Packaging
- 1g
- Price
- $75.14
- Updated
- 2021/12/16
4-Iodopyridine Chemical Properties,Usage,Production
Chemical Properties
White to off-white crystals,turns brown on storage
Uses
4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.
Synthesis
110-86-1
15854-87-2
GENERAL METHODS: [Li(TMP)Zn(tBu)2] 1 was prepared according to literature methods in a 0.4 mmol scale solution of THF. Pyridine (0.032 mL, 0.4 mmol) was added to this solution at 0°C and the resulting light orange colored reaction mixture was allowed to stir for 2 h at room temperature. Subsequently, the reaction was quenched with I2 (508 mg, dissolved in 1 mL THF) and stirring was continued for 1 hour. A 10% Na2S2O3 solution was added until the color of the reaction mixture faded, and then the product was extracted with DCM (3 x 1 mL). The organic extracts were combined, dried with MgSO4 and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography using EtOAc:heptane (20:80→30:70) as eluent to afford 4-iodopyridine (compound 5a) as an off-white solid (42 mg, 50% yield).1H NMR (400 MHz, CDCl3) δ ppm 7.59-7.86 (m, 2H), 8.07-8.44 (m 2H).
References
[1] Tetrahedron Letters, 2011, vol. 52, # 36, p. 4590 - 4594
[2] Journal of Organic Chemistry, 1984, vol. 49, # 20, p. 3857 - 3859
4-Iodopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
4-Iodopyridine Suppliers
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View Lastest Price from 4-Iodopyridine manufacturers
- Product
- 4-Iodopyridine 15854-87-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-19
- Product
- 4-iodopyridine 15854-87-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1000
- Release date
- 2023-04-20
- Product
- 4-Iodopyridine 15854-87-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 100 tons
- Release date
- 2022-02-08