ChemicalBook > CAS DataBase List > (4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one
(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one
- Product Name
- (4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one
- CAS No.
- 514-07-8
- Chemical Name
- (4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one
- Synonyms
- Tarxerone;Taraxeron;Taraxera-14-ene-3-one;D-Friedoolean-14-en-3-one;27-Norolean-14-en-3-one,13-methyl-, (13a)-;27-Norolean-14-en-3-one, 13-methyl-, (13α)-;Taraxerone, 98%, from Adenophora tetraphylla(Thunb.)Fisch;Aldehyde Dehydrogenase (ALDH),Taraxerone,Inhibitor,alcohol,enhancer,ALDH,inhibit,ADH;(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one;(4aR,6aR,8aR,12aR,12bS,14aR,14bR)-4,4,6a,8a,11,11,12b,14b-Octamethyl-1,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydropicen-3(2H)-one
- CBNumber
- CB71254045
- Molecular Formula
- C30H48O
- Formula Weight
- 424.7
- MOL File
- 514-07-8.mol
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(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Property
- Melting point:
- 241-243 °C
- Boiling point:
- 488.3±44.0 °C(Predicted)
- Density
- 1.01±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- form
- Solid
- color
- White to off-white
- LogP
- 10.480 (est)
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Safety
- HS Code
- 29143990
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N-Bromosuccinimide Price
Biosynth Carbosynth
- Product number
- FT65698
- Product name
- Taraxerone
- Packaging
- 1mg
- Price
- $60
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FT65698
- Product name
- Taraxerone
- Packaging
- 2mg
- Price
- $100
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FT65698
- Product name
- Taraxerone
- Packaging
- 5mg
- Price
- $175
- Updated
- 2021/12/16
AK Scientific
- Product number
- W2550
- Product name
- Taraxerone
- Packaging
- 2mg
- Price
- $185
- Updated
- 2021/12/16
AK Scientific
- Product number
- W2550
- Product name
- Taraxerone
- Packaging
- 5mg
- Price
- $286
- Updated
- 2021/12/16
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(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from light bamboo leaves and dandelion.
Uses
Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].
Definition
ChEBI: A natural product found in Cupania cinerea.
in vivo
Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1]. Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].
References
[1] Sung CK, et al. Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.Food Chem Toxicol. 2012 Jul;50(7):2508-14. DOI:10.1016/j.fct.2012.04.031
(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
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(4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one Suppliers
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View Lastest Price from (4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-one manufacturers
Career Henan Chemical Co
- Product
- Taraxerone 514-07-8
- Price
- US $8.00/KG
- Min. Order
- 1KG
- Purity
- ＞98% HPLC
- Supply Ability
- 20 tons
- Release date
- 2020-02-17
514-07-8, (4aS,6aS,6aR,8aR,12aS,14aS,14bS)-4,4,6a,6a,8a,11,11,14b-octamethyl-2,4 a,5,6,8,9,10,12,12a,13,14,14a-dodecahydro-1H-picen-3-oneRelated Search:
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