6-Chloropyridazin-3-ol
Uses- Product Name
- 6-Chloropyridazin-3-ol
- CAS No.
- 19064-67-6
- Chemical Name
- 6-Chloropyridazin-3-ol
- Synonyms
- Nsc75071;3-Chloro-6-pyridazone;6-Chloropyridazin-3-ol;6-Chloro-3-pyridazinol;6-Chloropyridazine-3-ol;6-Chloropyridazin-3(2H)-one;3-chloro-1H-pyridazin-6-one;3-Hydroxy-6-chloropyridazine;3-Chloro-6-hydroxypyridazine;6-Chloro-3-hydroxypyridaz...
- CBNumber
- CB71261274
- Molecular Formula
- C4H3ClN2O
- Formula Weight
- 130.53
- MOL File
- 19064-67-6.mol
6-Chloropyridazin-3-ol Property
- Melting point:
- 140.0 to 144.0 °C
- Density
- 1.55±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 9.80±0.40(Predicted)
- color
- White to Almost white
- InChI
- InChI=1S/C4H3ClN2O/c5-3-1-2-4(8)7-6-3/h1-2H,(H,7,8)
- InChIKey
- YICPBKWYZXFJNB-UHFFFAOYSA-N
- SMILES
- C1(=O)NN=C(Cl)C=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- SYX00271
- Product name
- 6-Chloro-3-hydroxypyridazine
- Packaging
- 1g
- Price
- $42.8
- Updated
- 2025/07/31
- Product number
- CVT00040
- Product name
- 6-Chloro-3-pyridazinol
- Packaging
- 1g
- Price
- $143
- Updated
- 2025/07/31
- Product number
- C2377
- Product name
- 6-Chloro-3(2H)-pyridazinone
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $48
- Updated
- 2025/07/31
- Product number
- C2377
- Product name
- 6-Chloro-3(2H)-pyridazinone
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $170
- Updated
- 2025/07/31
- Product number
- C596225
- Product name
- 6-Chloropyridazin-3(2H)-one
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
6-Chloropyridazin-3-ol Chemical Properties,Usage,Production
Uses
6-Chloropyridazin-3(2h)-one (cas# 19064-67-6) is a useful research chemical.
Synthesis
141-30-0
19064-67-6
General procedure for the synthesis of 3-hydroxy-6-chloropyridazine from 3,6-dichloropyridazine: to a solution of acetic acid/water (5:1, 20 mL) of 3,6-dichloropyridazine (1 g, 0.006759 mol) was added potassium acetate (0.662 g, 0.006759 mol), and the mixture was heated to 140 °C under microwave conditions for 70 min. After completion of the reaction, the reaction flask was cooled and the solvent was removed by vacuum evaporation. Ethyl acetate and water were added to the residue, the layers were separated and the aqueous layer was extracted with ethyl acetate. The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated to give 6-chloro-2H-pyridazin-3-one (0.813 g, 92.5% yield). The product was characterized by 1H NMR (CDCl3): δ 6.96 (d, 1H), 7.25 (d, 1H).
References
[1] Organic and Biomolecular Chemistry, 2008, vol. 6, # 1, p. 175 - 186
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 14, p. 3649 - 3657
[3] Organic Letters, 2011, vol. 13, # 2, p. 272 - 275
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 2, p. 1226 - 1229
[5] Patent: WO2007/8144, 2007, A1. Location in patent: Page/Page column 31
6-Chloropyridazin-3-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Chloropyridazin-3-ol manufacturers
- Product
- 6-Chloro-3-hydroxypyridazine 19064-67-6
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 3-Chloro-6-hydroxypyridazine 19064-67-6
- Price
- US $0.00/KG
- Min. Order
- 1g
- Purity
- 98%minHPLC
- Supply Ability
- 1Ton/month
- Release date
- 2021-11-08
- Product
- 6-Chloropyridazin-3-ol 19064-67-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-11-01