4,6-Dimethyl-2-hydroxypyrimidine

Product Name: 4,6-Dimethyl-2-hydroxypyrimidine
CAS No.: 108-79-2
Chemical Name: 4,6-Dimethyl-2-hydroxypyrimidine
Synonyms: 2-HYDROXY-4,6-DIMETHYLPYRIMIDINE;4,6-Dimethyl-2-pyrimidone;4,6-DIMETHYLPYRIMIDIN-2-OL;4,6-dimethyl-1,2-dihydro-2-pyrimidone;TIMTEC-BB SBB004271;4,6-Dimethyl-2-pyrimidol;4,6-DIMETHYL-2-PYRIMIDINOL;4,6-Dimethyl-2-pyrimidinone;4,6-Dimethyl-2(1H)-pyrimidone;4,6-dimethyl-2(1h)-pyrimidinon
CBNumber: CB7129502
Molecular Formula: C6H8N2O
Formula Weight: 124.14
MOL File: 108-79-2.mol

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4,6-Dimethyl-2-hydroxypyrimidine Property

Melting point:: 201-205 °C
Boiling point:: 230.92°C (rough estimate)
Density: 1.1683 (rough estimate)
refractive index: 1.5378 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 10.34±0.10(Predicted)
form: Solid
color: Off-White to Pale Yellow
CAS DataBase Reference: 108-79-2(CAS DataBase Reference)
NIST Chemistry Reference: 4,6-Dimethyl-2-pyrimidinol(108-79-2)
EPA Substance Registry System: 2(1H)-Pyrimidinone, 4,6-dimethyl- (108-79-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25-45-37-28
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D2427
Product name: 4,6-Dimethyl-2-hydroxypyrimidine
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $50
Updated: 2025/07/31

TCI Chemical

Product number: D2427
Product name: 4,6-Dimethyl-2-hydroxypyrimidine
Purity: >98.0%(HPLC)(T)
Packaging: 100g
Price: $148
Updated: 2025/07/31

TCI Chemical

Product number: D2427
Product name: 4,6-Dimethyl-2-hydroxypyrimidine
Purity: >98.0%(HPLC)(T)
Packaging: 500g
Price: $583
Updated: 2025/07/31

TRC

Product number: D476275
Product name: 4,6-Dimethyl-2-hydroxypyrimidine
Packaging: 100g
Price: $245
Updated: 2021/12/16

TRC

Product number: D476275
Product name: 4,6-Dimethyl-2-hydroxypyrimidine
Packaging: 5g
Price: $50
Updated: 2021/12/16

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4,6-Dimethyl-2-hydroxypyrimidine Chemical Properties,Usage,Production

Chemical Properties

Off-white, light yellow to pink crystalline powder

Uses

4,6-Dimethyl-2-hydroxypyrimidine is a component of Nicarbazine (N394530), a coccidiostat, which is an antiprotozoal agent that acts upon Coccidia parasites.

Synthesis

57-13-6

123-54-6

108-79-2

IM06: Synthesis of 4,6-dimethylpyrimidin-2-one Step 1: Urea (20.0 g, 333.3 mmol) and acetylacetone (33.3 g, 333.3 mmol) were dissolved in ethanol (166 mL), followed by the slow addition of concentrated aqueous hydrochloric acid solution (45 mL). The reaction mixture was stirred at 80 °C for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature, the precipitate was collected by filtration and washed with cold ethanol to afford 4,6-dimethylpyrimidin-2-ol as a colorless solid (40 g, 97% yield). The product was characterized by 1H NMR (DMSO-d6, 400 MHz): δ 7.35 (1H, s), 2.43 (6H, s).

Purification Methods

Crystallise the pyrimidine from absolute EtOH (charcoal). [Beilstein 24/2 V 138.]

References

[1] Patent: US2013/5743, 2013, A1. Location in patent: Page/Page column 12
[2] Patent: WO2013/4617, 2013, A1. Location in patent: Page/Page column 30
[3] European Journal of Inorganic Chemistry, 2018, vol. 2018, # 23, p. 2695 - 2701

4,6-Dimethyl-2-hydroxypyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

2-AMINO-6-METHYLPYRIMIDINE-4-CARBOXAMIDINE 2-AMINO-4-CYANO-6-METHYLPYRIMIDINE 2-CHLORO-6-METHYLPYRIMIDINE-4-CARBONITRILE

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4,6-Dimethyl-2-hydroxypyrimidine Suppliers

Americas 1 Belgium 1 China 149 Europe 4 Germany 3 India 12 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 3 Ukraine 2 United Kingdom 11 United States 35 Global 228

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

Kanto Chemical Co., Inc.

Tel: --
Fax: --
Email: reag-info@gms.kanto.co.jp
Country: Japan
ProdList: 6756
Advantage: 74

Wako Pure Chemical Industries, Ltd.

Tel: --
Fax: --
Email: labchem-tec@wako-chem.co.jp
Country: Japan
ProdList: 6819
Advantage: 80

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View Lastest Price from 4,6-Dimethyl-2-hydroxypyrimidine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 4,6-Dimethyl-2-hydroxypyrimidine 108-79-2
Price: US $100.00-50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-11-12

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 4,6-Dimethyl-2-hydroxypyrimidine 108-79-2
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2021-09-24

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 4,6-Dimethyl-2-hydroxypyrimidine 108-79-2
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10KG
Release date: 2021-09-24

108-79-2, 4,6-Dimethyl-2-hydroxypyrimidineRelated Search:

Dimethicone 4-Cyanophenol CHLOROPHOSPHONAZO III Dimethyl phthalate Dimethyl carbonate N,N-Dimethylformamide Dimethyl fumarate Dimethyl ether Dimethyl sulfoxide Dimethyl sulfate Dacthal ETHANE 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL 2-Hydroxypyrimidine Dimethyl disulfide Poly(dimethylsiloxane) 4,6-Dihydroxypyrimidine 4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE,4,6-DIMETHYL-2-HYDROXYPYRIMIDINE HYDROCHLORIDE 97+%

2(1H)-Pyrimidinone, 4,6-dimethyl-

4,6-dimethyl-2(1h)-pyrimidinon

4,6-Dimethyl-2(3H)-pyrimidinone

4,6-Dimethyl-2-pyrimidone

2-HYDROXY-4,6-DIMETHYLPYRIMIDINE

4,6-DIMETHYL-2-HYDROXYPYRIMIDINE

4,6-DIMETHYLPYRIMIDIN-2-OL

4,6-DIMETHYL-2-PYRIMIDINOL

TIMTEC-BB SBB004271

2(1H)-Pyrimidinone, 4,6-dimethyl- (7CI,8CI,9CI)

4,6-Dimethyl-2-hydroxypyrimidine,97%

4,6-dimethyl-1,2-dihydro-2-pyrimidone

6-DiMethyl-2-hydroxypyriMidine

4,6-DIMETHYLPYRIMIDIN-2-OL HYDROCHLORIDE

4,6-DIMETHYL-2-HYDROXYPYRIMIDINE 98%

4,6-Dimethyl-2-hydroxypyrimidine, 4,6-Dimethyl-2-pyrimidinone

4,6-Dimethyl-2-pyrimidol

4,6-Dimethyl-2-hydroxypyrimidine ,98%

4,6-Dimethyl-2(1H)-pyrimidone

4,6-Dimethylpyrimidin-2(1H)-one

2-Hydroxy-4,6-dimethylpyrimidine,97%

4,6-Dimethyl-2-pyrimidinone

4,6-Dimethyl-2-pyrimidinol 2-Hydroxy-4,6-dimethylpyrimidine

4,6-Dimethyl-2-hydroxypyrimidine &gt

4,6-Dimethyl-2-hydroxypyrimidine ISO 9001：2015 REACH

4,6-DIMETHYL-2(1H)-PYRIMIDINONE

108-79-2

6622-38-9

PYRIMIDINE

Pyridines, Pyrimidines, Purines and Pteredines

Heterocycle-Pyrimidine series

alcohol