kaempferol 3-O-sophoroside
- Product Name
- kaempferol 3-O-sophoroside
- CAS No.
- 19895-95-5
- Chemical Name
- kaempferol 3-O-sophoroside
- Synonyms
- Sophoraflavonoloside;Kaempferol-3-O-β-D-sophoroside;Kaempferol 3-O-beta-D-sophoroside;-Sophoroside;Sophoraflavanoloside;Kaempferol 3-sophoroside;Kaempferol 3-β-sophoroside;kaempferol 3-O-sophoroside;KaeMpferol-3-O- sophroside;Kaempferol 3-2-Sophoroside
- CBNumber
- CB71307202
- Molecular Formula
- C27H30O16
- Formula Weight
- 610.52
- MOL File
- 19895-95-5.mol
kaempferol 3-O-sophoroside Property
- Melting point:
- 194-198℃
- Boiling point:
- 995.0±65.0 °C(Predicted)
- Density
- 1.82
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 6.20±0.40(Predicted)
- form
- Solid
- color
- Light Yellow
- InChIKey
- LKZDFKLGDGSGEO-CCMCOHMBNA-N
Safety
- Toxicity
- LD50 intraperitoneal in mouse: > 1gm/kg
N-Bromosuccinimide Price
- Product number
- K100020
- Product name
- Kaempferol3-β-Sophoroside
- Packaging
- 10mg
- Price
- $275
- Updated
- 2021/12/16
- Product number
- K100020
- Product name
- Kaempferol3-β-Sophoroside
- Packaging
- 25mg
- Price
- $545
- Updated
- 2021/12/16
- Product number
- orb594059
- Product name
- Kaempferol-3-O-sophoroside
- Packaging
- 10mg
- Price
- $654.5
- Updated
- 2021/12/16
- Product number
- 96304
- Product name
- Kaempferol3-β-sophoroside
- Packaging
- 5mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- CS-0018544
- Product name
- Kaempferol3-O-sophoroside
- Packaging
- 5mg
- Price
- $315
- Updated
- 2021/12/16
kaempferol 3-O-sophoroside Chemical Properties,Usage,Production
Chemical Properties
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from mulberry leaves, Hedyotis diffusa, and roses.
Uses
Kaempferol 3-β-Sophoroside is a derivative of Kaempferol (K100000), a plant flavonoid which play a beneficial role in human health promotion.
Definition
ChEBI: A kaempferol O-glucoside that is kaempferol attached to a beta-D-sophorosyl residue at position 3 via a glycosidic linkage.
in vivo
Kaempferol 3-O-sophoroside (10 and 20 mg/kg, p.o., once daily for 20 days) binds to AMP-activated protein kinase (AMPK) to promote brain-derived neurotrophic factor (BDNF) production and autophagy enhancement in corticosterone (HY-B1618)-induced mouse depression model and chronic unpredictable mild stress (CUMS) model, ultimately achieving antidepressant effects[3]. Kaempferol 3-O-sophoroside (100 and 200 mg/kg, p.o., 30-minute administration duration) exhibits analgesic effects in the acetic acid-induced writhing mice model[4].
| Animal Model: | Acetic acid-induced writhing mice model[4] |
| Dosage: | 50, 100, 200 mg/kg |
| Administration: | Oral gavage (p.o.), administration duration of 30 minutes |
| Result: | Caused dose-dependent inhibition of the writhing response induced by acetic acid. |
| Animal Model: | Corticosterone (HY-B1618)-induced mouse depression model; Chronic unpredictable mild stress (CUMS) model[3] |
| Dosage: | 10 and 20 mg/kg |
| Administration: | Oral gavage (p.o.), once per day for 20 consecutive days |
| Result: | Ameliorated weight loss, dyskinesia, and hippocampal volume reduction induced by Corticosterone and CUMS. |
IC 50
TLR2; TLR4
kaempferol 3-O-sophoroside Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from kaempferol 3-O-sophoroside manufacturers
- Product
- kaempferol 3-O-sophoroside 19895-95-5
- Price
- US $35.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-28
- Product
- Kaempferol-3-O-sophoroside 19895-95-5
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-02
- Product
- Sophoraflavonoloside 19895-95-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 1000kg
- Release date
- 2018-12-25