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isorhapontigenin

Product Name
isorhapontigenin
CAS No.
32507-66-7
Chemical Name
isorhapontigenin
Synonyms
100mg;100MG/1G/100G;Isorhapotigenin;Isorhapotogenin;sorhapontigenin;isorhapontigenin;isorhapontigenin, Ⅰ;Isorhapontigenin>Isorhapontigenin-RM;3′-Methoxyresveratrol
CBNumber
CB71359973
Molecular Formula
C15H14O4
Formula Weight
258.27
MOL File
32507-66-7.mol
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isorhapontigenin Property

Melting point:
180.0 to 184.0 °C
Boiling point:
471.8±35.0 °C(Predicted)
Density 
1.345
storage temp. 
room temp
solubility 
DMSO: soluble15mg/mL, clear
pka
9.16±0.10(Predicted)
form 
powder
color 
white to light brown
InChI
InChI=1S/C15H14O4/c1-19-15-8-10(4-5-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
InChIKey
ANNNBEZJTNCXHY-NSCUHMNNSA-N
SMILES
C1(O)=CC(/C=C/C2=CC=C(O)C(OC)=C2)=CC(O)=C1
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-43-51
Safety Statements 
26-36/37/39
WGK Germany 
3
HS Code 
2909.50.5000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0590
Product name
Isorhapontigenin
Purity
≥98% (HPLC)
Packaging
5mg
Price
$125.4
Updated
2025/07/31
Sigma-Aldrich
Product number
SML0590
Product name
Isorhapontigenin
Purity
≥98% (HPLC)
Packaging
25mg
Price
$510
Updated
2025/07/31
Sigma-Aldrich
Product number
PHL84227
Product name
Isorhapontigenin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$363
Updated
2025/07/31
TCI Chemical
Product number
I0804
Product name
Isorhapontigenin
Purity
>96.0%(GC)
Packaging
100mg
Price
$103
Updated
2025/07/31
TRC
Product number
I779135
Product name
Isorhapontigenin
Packaging
2mg
Price
$60
Updated
2021/12/16
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isorhapontigenin Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Belamcanda chinensis.

Uses

Isorhapontigenin, an orally bioavailable dietary polyphenol isolated from the Chinese herb Gnetum cleistostachyum, displays anti-inflammatory effects. Isorhapontigenin induces autophagy and inhibits invasive bladder cancer formation[1][2].

Definition

ChEBI: Isorhapontigenin is a stilbenoid.

Biochem/physiol Actions

Isorhapontigenin or 4-methoxyresveratrol is a stilbene derivative isolated from a number of plants including Chinese medical herbs Gnetum Cleistostachyum and Iris Domestica (Belamcanda chinensis, leopard lily), and wine grapes. Similarly to resveratrol, isorhapontigenin is a potent antioxidant that attenuates ROS generation. Also, Isorhapontigenin exhibits pro-apoptopic and anti-cancer activities through downregulation of XIAP (X-linked inhibitor of apoptosis protein).

References

[1] Yeo SCM, et al. Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid-independent mechanism. Br J Pharmacol. 2017 Jul;174(13):2043-2059. DOI:10.1111/bph.13803
[2] Liang Y, et al. SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin (ISO) on human bladder cancers. Autophagy. 2016 Aug 2;12(8):1229-39. DOI:10.1080/15548627.2016.1179403
[3] Jiang G, et al. Isorhapontigenin (ISO) Inhibits Invasive Bladder Cancer Formation In Vivo and Human Bladder Cancer Invasion In Vitro by Targeting STAT1/FOXO1 Axis. Cancer Prev Res (Phila). 2016 Jul;9(7):567-80. DOI:10.1158/1940-6207.CAPR-15-0338

isorhapontigenin Preparation Products And Raw materials

Raw materials

Preparation Products

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isorhapontigenin Suppliers

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View Lastest Price from isorhapontigenin manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Isorhapontigenin 32507-66-7
Price
US $0.00/kg
Min. Order
1kg
Purity
>98%
Supply Ability
1000 kg
Release date
2024-04-25
PNP Biotech Co. Ltd
Product
Isorhapontigenin 32507-66-7
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2022-10-25
Shanghai Standard Technology Co., Ltd.
Product
Isorhapontigenin 32507-66-7
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-18

32507-66-7, isorhapontigeninRelated Search:

alpha-Cyperone Hydroxyecdysone alpha-Terpineol beta-Sitosterol MOSLOFLAVONE Artemether Baicalin (E)-3-Hydroxy-4',5-dimethoxystilbene Acetyl-trans-resveratrol PICEATANNOL Oxyresveratrol 3'-Hydroxypterostilbene Cimifugin Belamcanda chinensis extract Aloe emodin Emodin-3-methyl ether Emodin rhapontigenin

  • isorhapontigenin
  • (E)-3,4',5-Trihydroxy-3'-methoxystilbene
  • (E)-3'-Methoxystilbene-3,4',5-triol
  • (E)-3-Methoxy-stilbene-4,3',5'-triol
  • 5-[(E)-2-(4-Hydroxy-3-methoxyphenyl)ethenyl]-1,3-benzenediol
  • 100MG/1G/100G
  • 3,4',5-Trihydroxy-3'-methoxy-trans-stilbene
  • 100mg
  • (E)-3'-Methoxy-3,4',5-stilbenetriol
  • (E)-5-[2-(4-Hydroxy-3-methoxyphenyl)ethenyl]-1,3-benzenediol
  • 3′-Methoxyresveratrol
  • Isorhapotigenin
  • Isorhapotogenin
  • isorhapontigenin, Ⅰ
  • 5-[(1E)-2-(4-Hydroxy-3-methoxyphenyl)ethenyl]-1,3-benzenediol
  • sorhapontigenin
  • Isorhapontigenin ?(E)-3,4',5-Trihydroxy-3'-methoxystilbene
  • 5-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]benzene-1,3-diol
  • Isorhapontigenin&gt
  • 1,3-Benzenediol, 5-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-
  • (E)-5-(4-hydroxy-3-methoxystyryl)benzene-1,3-diol
  • 5-[(1E)-2-(4- hydroxy -3- methoxyphenyl) vinyl ]-1,3- hydroquinone
  • Isorhapontigenin-RM
  • Isorhapontigenin, 10 mM in DMSO
  • 32507-66-7