ChemicalBook > CAS DataBase List > N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

Product Name
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine
CAS No.
231278-20-9
Chemical Name
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine
Synonyms
in-4-amine;)-6-iodoquinazoL;Lapatinib Impurity 25;Lapatinib Intermediate 2;N-(3-Chloro-4-((3-fluorobenzyl);N-[3-Chloro-4-(3-fluorobenzyloxy);N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-;N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquin;[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazol;6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline
CBNumber
CB71456991
Molecular Formula
C21H14ClFIN3O
Formula Weight
505.71
MOL File
231278-20-9.mol
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N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Property

Melting point:
222-224°C
Boiling point:
581.3±50.0 °C(Predicted)
Density 
1.691±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
5.04±0.50(Predicted)
form 
Solid
color 
Yellow to Dark Yellow
Water Solubility 
Slightly soluble in water.
Sensitive 
Light Sensitive
CAS DataBase Reference
231278-20-9(CAS DataBase Reference)
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Safety

HS Code 
2933.59.8000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C2965
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$53
Updated
2024/03/01
TCI Chemical
Product number
C2965
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$154
Updated
2024/03/01
Alfa Aesar
Product number
H54229
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline, 97%
Packaging
250mg
Price
$202
Updated
2024/03/01
Alfa Aesar
Product number
H54229
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline, 97%
Packaging
1g
Price
$602
Updated
2024/03/01
TRC
Product number
B807825
Product name
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine
Packaging
500mg
Price
$55
Updated
2021/12/16
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N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Chemical Properties,Usage,Production

Description

N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-quinazolin-4-amine is a quinazoline derivative that has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.

Chemical Properties

Yellow Solid

Uses

Lapatinib intermediate

Uses

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline is used as an organic chemical synthesis intermediate.

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Suppliers

Changzhou Idea-Works Medical Technology Co., Ltd
Tel
0519-83879978
Email
sales@ideaworkspharm.com
Country
China
ProdList
85
Advantage
62
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine manufacturers

Nanjing Fred Technology Co., Ltd
Product
N-{3-chloro-4-[(3-fluorobenzyl)-oxy]phenyl}-6-iodoquinazolin-4-amine 231278-20-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-29
WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine 231278-20-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
200kg
Release date
2021-08-25
Hebei Mojin Biotechnology Co.,Ltd
Product
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine 231278-20-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-22

231278-20-9, N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amineRelated Search:


  • N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine
  • N-{3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl}-6-iodo-4-quinazolinamine
  • 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline
  • N-[3-Chloro-4-(3-fluorobenzyloxy) phenyl]-6-iodoquinazolin-5-amine
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazolin
  • N-(3-Chloro-4-((3-fluorobenzyl)
  • Lapatinib Impurity 25
  • N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine
  • Lapatinib Intermediate 2
  • [3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazol
  • N-{3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl}-6-iodoquinazolin-4-aMine
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylaMino]-6-iodoquinazoline, 97%
  • N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-iodoquinazolin-4-aMine
  • [3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-iodo-quinazolin-4-yl)-aMine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-
  • N-(4-(3-Fluorobenzoyloxy)-3-chlorophenyl)-6-iodo quinazolin-4-aMine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazoline-4-aMine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-aMi
  • N-[3-chloro -4-(3- fluorinebenzyl)phenyl]-6-iodinequinazolin -4-aMine
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline &gt
  • )-6-iodoquinazoL
  • in-4-amine
  • 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline,97%
  • N-[3-Chloro-4-(3-fluorobenzyloxy)
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-iodoquinazoline
  • N-[3-Chloro-4-(3-Fluorobenzyloxy)-Phenyl]-6-Iodoquinazolin-4-Amine(For export only)
  • N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquin
  • N-[3-Chloro-4-[(3-fluorophenyl)oxy]-phenyl]iodo-4-quinazolinamine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4...
  • N - [3-chloro-4 - (3-fluorobenzyloxy) phenyl] - 6-iodoquinozoline-5-amine
  • 231278-20-9
  • 31278-20-9
  • 291278-20-9
  • C21H14ClFIN3O
  • Lapatinib
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical intermediate
  • Various Intermediates
  • Intermediate of lapatinib ditosylate