ChemicalBook > CAS DataBase List > N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine

Product Name
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine
CAS No.
231278-20-9
Chemical Name
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine
Synonyms
in-4-amine;)-6-iodoquinazoL;Lapatinib Impurity 25;Lapatinib Intermediate 2;N-(3-Chloro-4-((3-fluorobenzyl);N-[3-Chloro-4-(3-fluorobenzyloxy);N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-;N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquin;[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazol;6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline
CBNumber
CB71456991
Molecular Formula
C21H14ClFIN3O
Formula Weight
505.71
MOL File
231278-20-9.mol
More
Less

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Property

Melting point:
222-224°C
Boiling point:
581.3±50.0 °C(Predicted)
Density 
1.691±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
5.04±0.50(Predicted)
form 
Solid
color 
Yellow to Dark Yellow
Water Solubility 
Slightly soluble in water.
Sensitive 
Light Sensitive
CAS DataBase Reference
231278-20-9(CAS DataBase Reference)
More
Less

Safety

HS Code 
2933.59.8000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C2965
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$53
Updated
2024/03/01
TCI Chemical
Product number
C2965
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$154
Updated
2024/03/01
Alfa Aesar
Product number
H54229
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline, 97%
Packaging
250mg
Price
$202
Updated
2024/03/01
Alfa Aesar
Product number
H54229
Product name
4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline, 97%
Packaging
1g
Price
$602
Updated
2024/03/01
TRC
Product number
B807825
Product name
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine
Packaging
500mg
Price
$55
Updated
2021/12/16
More
Less

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Chemical Properties,Usage,Production

Description

N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-quinazolin-4-amine is a quinazoline derivative that has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.

Chemical Properties

Yellow Solid

Uses

Lapatinib intermediate

Uses

4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline is used as an organic chemical synthesis intermediate.

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
CMS Chemicals Limited
Tel
--
Fax
--
Email
cms.marketing@cms-chemicals.com
Country
United Kingdom
ProdList
3708
Advantage
60
More
Less

View Lastest Price from N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine manufacturers

Nanjing Fred Technology Co., Ltd
Product
N-{3-chloro-4-[(3-fluorobenzyl)-oxy]phenyl}-6-iodoquinazolin-4-amine 231278-20-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-29
WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine 231278-20-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
200kg
Release date
2021-08-25
Hebei Mojin Biotechnology Co.,Ltd
Product
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine 231278-20-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-22

231278-20-9, N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amineRelated Search:


  • N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-amine
  • N-{3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl}-6-iodo-4-quinazolinamine
  • 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline
  • N-[3-Chloro-4-(3-fluorobenzyloxy) phenyl]-6-iodoquinazolin-5-amine
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazolin
  • N-(3-Chloro-4-((3-fluorobenzyl)
  • Lapatinib Impurity 25
  • N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine
  • Lapatinib Intermediate 2
  • [3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazol
  • N-{3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl}-6-iodoquinazolin-4-aMine
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylaMino]-6-iodoquinazoline, 97%
  • N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-iodoquinazolin-4-aMine
  • [3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-iodo-quinazolin-4-yl)-aMine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-
  • N-(4-(3-Fluorobenzoyloxy)-3-chlorophenyl)-6-iodo quinazolin-4-aMine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazoline-4-aMine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4-aMi
  • N-[3-chloro -4-(3- fluorinebenzyl)phenyl]-6-iodinequinazolin -4-aMine
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline &gt
  • )-6-iodoquinazoL
  • in-4-amine
  • 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)phenylamino]-6-iodoquinazoline,97%
  • N-[3-Chloro-4-(3-fluorobenzyloxy)
  • 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-iodoquinazoline
  • N-[3-Chloro-4-(3-Fluorobenzyloxy)-Phenyl]-6-Iodoquinazolin-4-Amine(For export only)
  • N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquin
  • N-[3-Chloro-4-[(3-fluorophenyl)oxy]-phenyl]iodo-4-quinazolinamine
  • N-[3-Chloro-4-(3-fluorobenzyloxy)-phenyl]-6-iodoquinazolin-4...
  • N - [3-chloro-4 - (3-fluorobenzyloxy) phenyl] - 6-iodoquinozoline-5-amine
  • 231278-20-9
  • 31278-20-9
  • 291278-20-9
  • C21H14ClFIN3O
  • Lapatinib
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical intermediate
  • Various Intermediates
  • Intermediate of lapatinib ditosylate