tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

Product Name: tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate
CAS No.: 877399-74-1
Chemical Name: tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate
Synonyms: 1-(1-Boc-4-piperidyl)pyrazole-4-boronic acid pinacol ester;tert-butyl 4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate;tert-Butyl 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylate;4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-piperidine-1-carboxylic acid tert-butyl ester;Crizotinib Impurity 2;Crizotinib Impurity 1;CrizotinibIntermediate4;Crizotinib intermediates 2;InterMediate Ⅱ of Crizotinib;Borate fragment of crizotinib
CBNumber: CB71504562
Molecular Formula: C19H32BN3O4
Formula Weight: 377.29
MOL File: 877399-74-1.mol

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tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate Property

Melting point:: 114.0 to 118.0 °C
Boiling point:: 492.8±35.0 °C(Predicted)
Density: 1.14±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
form: powder to crystal
pka: 2.89±0.19(Predicted)
color: White to Almost white
InChI: InChI=1S/C19H32BN3O4/c1-17(2,3)25-16(24)22-10-8-15(9-11-22)23-13-14(12-21-23)20-26-18(4,5)19(6,7)27-20/h12-13,15H,8-11H2,1-7H3
InChIKey: QSQWENQPOSRWLP-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC(N2C=C(B3OC(C)(C)C(C)(C)O3)C=N2)CC1

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5002
Product name: tert-Butyl 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylate
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $179
Updated: 2024/03/01

TCI Chemical

Product number: B5002
Product name: tert-Butyl 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylate
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $536
Updated: 2024/03/01

TRC

Product number: B663855
Product name: 1-(1-Boc-4-piperidyl)pyrazole-4-boronicAcidPinacolEster
Packaging: 1g
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB32980
Product name: tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate
Packaging: 5G
Price: $50
Updated: 2021/12/16

AK Scientific

Product number: X4864
Product name: 1-(1-Boc-4-piperidyl)pyrazole-4-boronicAcidPinacolEster
Packaging: 5g
Price: $52
Updated: 2021/12/16

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tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate Chemical Properties,Usage,Production

Synthesis

Synthesis of tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate from 1-Boc-4-(4-Iodo-1H-pyrazol-1-yl)piperidine and 1-4,4,4',4',5,5,5',5'-Octamethyl-2,2'-bi(1,3,2-dioxaborolane), which can also be obtained by purification and isolation from tert-Butyl 4-((methylsulfonyl)oxy)piperidine-1-carboxylate.

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tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate Suppliers

Americas 1 CHINA 334 Europe 1 India 4 Japan 1 United Kingdom 3 United States 16 Global 360

Hunan Eurasian Pharmaceutical Co. Ltd.

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SynthonTech.

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TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.

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J & K SCIENTIFIC LTD.

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Bayee Biotech (Anqing) Co., Ltd.

Tel: 0556-5032306 18917961636
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View Lastest Price from tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate manufacturers

Jinan Million Pharmaceutical Co., Ltd

Product: tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 877399-74-1
Price: US $1.00-0.50/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 200kg
Release date: 2023-12-11

Zison Pharmaceutical (Shandong) Co., Ltd.

Product: tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 877399-74-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ＞98% by HPLC
Supply Ability: 10kg/month
Release date: 2023-01-09

Henan Fengda Chemical Co., Ltd

Product: tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate 877399-74-1
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-31

877399-74-1, tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylateRelated Search:

Selenium dioxide Buprofezin tert-Butanol 2-Butoxyethanol 1,4-Dioxane Diethylene glycol monobutyl ether Cyhalofop-butyl Pyrazole Butyl acetate 2-Chloro-2-methylpropane Haloperidol Butyl acrylate tert-Butyl 4-broMo-1H-pyrrolo[2,3-c]pyridine-1-carboxylate tert-butyl 3-broMo-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate (R)-1-Boc-2-cyanopyrrolidine 1-N-Boc-3-hydroxyazetidine 3,5-Dimethyl-piperazine-1-carboxylic acid tert-butyl ester 1-Boc-3-(cyanomethylene)azetidine

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

1-(4-N-Boc-piperidine)pyrazole-4-boronic acid pinacol ester

<i>tert</i>-Butyl 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylate

tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-car

Crizotinib intermediates 2

1-Piperidinecarboxylic acid, 4

Borate fragment of crizotinib

Crizotinib Impurity 2

4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylatetert-Butyl

4-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL) -1H-PYRAZOL-1-YL]PIPERIDINE-1-CARBOXYLATE_ 877399-74-1

1-(1-Boc-piperidin-4-yl)-pyrazole-4-boronic acid picol ester

1-Piperidinecarboxylic acid, 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester

1-(1-Boc-4-piperidyl)pyrazole-4-boronic acid pinacol ester

4-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrazol-1-yl]-piperidine-1-carboxylic acid tert-butyl ester

4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl)piperidine-1-carb

tert-butyl 4-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H

1-Piperidinecarboxylic acid, 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-pyrazol-1-yl]-, 196%

tert-Butyl 4-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxyla

5-BroMo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylaMine

4-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOL-1-YL)PIPERIDINE-1-CARBOXYLATE

tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carbox

1-(1-Boc-piperidin-4-yl)-pyrazole-4-boronic acid pinacol ester

tert-butyl 4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate

tert-Butyl 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylate

tert-butyl 4-(3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrol-1-yl)piperidine-1-carboxylate

InterMediate Ⅱ of Crizotinib

tert-Butyl 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine-1-carboxylate &gt

4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-, 1,1-dimethylethyl ester

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-

4 - [4 - (4 - (4,4,5,5 31 - methyl - 1-2 oxygen mixed boron borane - 2 - base) - 1 h - pyrazole - 1 - base] piperidine - 1 - formic acid tert-butyl ester

2-[1-(1-Boc-piperidin-4-yl)pyrazol-4-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxylate ISO 9001：2015 REACH

Crizotinib Impurity 1

tert-butyl 4-(4-(4,4,5-trimethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate

1-(N-Boc-piperidine-4-ly)-boronicacid pinacol ester

CrizotinibIntermediate4

1-(N-Boc-piperidin-4-yl)-1H-pyrazole-4-boronic acid pinacol ester

877399-74-1

977399-74-1

977399-47-1

C19H32BN3O4