hexafluorobenzene

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hexafluorobenzene

Product Name: hexafluorobenzene
CAS No.: 392-56-3
Chemical Name: hexafluorobenzene
Synonyms: PERFLUOROBENZENE;CP28;1,2,3,4,5,6-hexafluoro-benzene;CP 28;hexafluoro-benzen;Hexafluorobenzene;Hexaflurorobenzene;benzene,hexafluoro-;Perfluorobenzene 99%;Hexafluorobenzene >
CBNumber: CB7152315
Molecular Formula: C6F6
Formula Weight: 186.05
MOL File: 392-56-3.mol

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hexafluorobenzene Property

Melting point:: 3.7-4.1 °C (lit.)
Boiling point:: 80-82 °C (lit.)
Density: 1.612 g/mL at 25 °C (lit.)
refractive index: n20/D 1.377(lit.)
Flash point:: 50 °F
storage temp.: Sealed in dry,Room Temperature
form: Liquid
Specific Gravity: 1.612
color: Clear colorless to slightly yellow
Water Solubility: Immiscible with water.
Merck: 14,4686
BRN: 1683438
Dielectric constant: 2.0499999999999998
Stability:: Stable. Incompatible with strong oxidizing agents. May form complexes with transition metals which can explode when heated. Highly flammable.
CAS DataBase Reference: 392-56-3(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, hexafluoro-(392-56-3)
EPA Substance Registry System: Benzene, hexafluoro- (392-56-3)

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-36/37/38
Safety Statements: 16-33-7/9-29-26-37/39
RIDADR: UN 1993 3/PG 2
WGK Germany: 3
RTECS: DA3050000
F: 10
Hazard Note: Highly Flammable
TSCA: Yes
HazardClass: 3
PackingGroup: II
HS Code: 29039990
Toxicity: guinea pig,LCLo,inhalation,11800ppm/4H (11800ppm),BEHAVIORAL: ATAXIASENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYELUNGS, THORAX, OR RESPIRATION: OTHER CHANGES,National Technical Information Service. Vol. OTS0571186,

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 326720
Product name: Hexafluorobenzene
Purity: ≥99.5%, NMR grade
Packaging: 5g
Price: $44.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 326720
Product name: Hexafluorobenzene
Purity: ≥99.5%, NMR grade
Packaging: 25g
Price: $131
Updated: 2024/03/01

TCI Chemical

Product number: H0085
Product name: Hexafluorobenzene
Purity: >99.0%(GC)
Packaging: 5g
Price: $30
Updated: 2024/03/01

TCI Chemical

Product number: H0085
Product name: Hexafluorobenzene
Purity: >99.0%(GC)
Packaging: 25g
Price: $78
Updated: 2024/03/01

Alfa Aesar

Product number: A11500
Product name: Hexafluorobenzene, 99%
Packaging: 10g
Price: $55.5
Updated: 2024/03/01

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hexafluorobenzene Chemical Properties,Usage,Production

Description

Hexafluorobenzene, HFB, C6F6, or perfluorobenzene is an organic, aromatic compound. In this derivative of benzene all hydrogen atoms have been replaced by fluorine atoms. The technical uses of the compound are limited, although it is recommended as a solvent in a number of photochemical reactions. In the laboratory hexafluorobenzene is used as standard in fluorine-19 NMR spectroscopy, solvent and standard in carbon-13 NMR, solvent in proton NMR, solvent when studying some parts in the infrared and solvent in ultraviolet–visible spectroscopy, as hexafluorobenzene itself hardly shows any absorbance in the UV region.

Chemical Properties

colourless liquid

Uses

Hexafluorobenzene is used as a solvent in photochemical reactions. It is also used as a reference compound in fluorine-19 NMR, carbon-13 NMR. It is used as a solvent in proton NMR, IR spectrum and UV-spectra. It is used as anticorrosive, antifriction and anti-tumor agents. Further, it is used as a reference molecule to investigate tissue oxygenation in vivo studies. It forms series of 1:1 complexes with naphthalene, anthracene, phenanthrene, pyrene and triphenylene.

Uses

Hexafluorobenzene can be used as a standard in ¹⁹Fluorine NMR (nuclear magnetic resonance) spectroscopy and also as a solvent in ¹³Carbon and ¹H NMR spectroscopy.

Definition

ChEBI: A member of the class of fluorobenzenes that is benzene in which all six hydrogen atom have been replaced by fluorine.

Application

Hexafluorobenzene can react with:
Ethyl magnesium bromide in the presence of transition metal halides to form the corresponding perfluoroarylmagnesium compound that can undergo Grignard reactions.
The sodium salt of the appropriate phenol in 1,3-dimethyl-2-imidazolidinone (DMEU) to form the corresponding hexakis(aryloxy)benzenes.
It can be used:
As a ligand to synthesize novel ruthenium(0) and osmium(0) hexafluorobenzene complexes.
As a solvent and promoter for the ring-closing metathesis (RCM) to form tetrasubstituted olefins in the presence of a ruthenium-based catalyst.

Reactions

For example, hexafluorobenzene adds chlorine quite readily under rather mild conditions to give hexachlorohexafluorocyclohexane. The catalytic reduction of hexafluorobenzene with hydrogen to penta. and tetra-fluorobenzene at 300 °C, using a platinum catalyst, probably proceeds by a free-radical mechanism. Although the addition of chlorine to hexafluorobenzene is an example of a free-radical addition reaction, the reduction of hexafluorobenzene with hydrogen is classified as a freeradical substitution reaction.
One of the earliest and, perhaps, most complicated reactions of hexafluorobenzene is one reported by Desirant. This interesting reaction, whic h is the only example of a high· temperature (above 300°C) reaction of hexafluorobenzene reported to date, involves the pyrolysis of the molecule in a platinum reactor at 850°C. Among the many products produced in this reaction , octafluorotoluene and decafluorobiphenyl were identified. This highly complex reaction probably could also be classified, in some respects, as a free-radical substitution reaction. There is also some less direct evidence that hightemperature reactions of hexafluorobe nzene do occur. In the synthesis of hexafluorobenzene by the pyrolysis of tribromofluoromethane, bromopentafluorobenzene is a signifi'cant by-product. Lesser amounts of higher brominated fluorocarbons are formed as well, along with copious quantities of bromine. This rather complex reaction is illustrated below.
CFBr3--630-640℃-->C6F6+Br2+C6F5Br+C6F4Br2+etc.

General Description

Hexafluorobenzene was repoted to be a sensitive ¹⁹F NMR indicator of tumor oxygenation. Rotational Raman spectra of hexafluorobenzenehas been studied under high resolution using a single mode argon laser as the exciting source. Hexafluorobenzene in the gas phase reacts spontaneously with lithium amalgam, to give a solid and intimate mixture of lithium fluoride and elemental polymeric carbon with a small amount of superstoichiometric lithium. Hexafluorobenzene forms series of 1:1 complexes with naphthalene, anthracene,phenanthrene, pyrene and triphenylene.

Hazard

Toxic by inhalation. Combustible.

Synthesis

The direct synthesis of hexafluorobenzene from benzene and fluorine is not possible. The synthetic route proceeds via the reaction of alkali-fluorides with halogenated benzene:
C6Cl6 + 6 KF → C6F6 + 6 KCl

Purification Methods

Main impurities are incompletely fluorinated benzenes. Purify it by standing in contact with oleum for 4hours at room temperature, repeating until the oleum does not become coloured. Wash it several times with water, then dry it with P2O5. Finally purify it by repeated fractional crystallisation. [Beilstein 5 III 523, 5 IV 640.]

hexafluorobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from hexafluorobenzene manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: HEXAFLUOROBENZENE 392-56-3
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-22

Henan Fengda Chemical Co., Ltd

Product: hexafluorobenzene 392-56-3
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

Hebei Mojin Biotechnology Co., Ltd

Product: Hexafluorobenzene 392-56-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-06-20

392-56-3, hexafluorobenzeneRelated Search:

Pentafluorobenzaldehyde Pentafluorobenzoyl chloride Bromopentafluorobenzene METHYL PENTAFLUOROBENZOATE Pentafluorophenol Pentafluorobenzene 1,3,5-Trifluorobenzene 1,2-Difluorobenzene Fluorobenzene 1,2,4,5-Tetrafluorobenzene 1,4-Difluorobenzene HYDROFLUORIC ACID 1,2,3-Trifluorobenzene 1,3-Difluorobenzene METHYL FLUORIDE hexafluorobenzene 1,2,3,5-Tetrafluorobenzene 1,2,4-Trifluorobenzene

1,2,3,4,5,6-Hexafluorobenzene

1,2,3,4,5,6-hexafluoro-benzene

benzene,hexafluoro-

CP 28

CP28

HEXAFLUOROBENZENE FOR SYNTHESIS

hexafluorobenzene radical cation

HEXAFLUOROBENZENE, NMR GRADE

1,2,3,4,5,6-Hexfluorobenzene

hexafluoro-benzen

HEXAFLUOROBENZENE, 99.5+%, NMR GRADE

HEXAFLUOROBENZENE, FOR NMR-SPECTROSCOPY

HEXAFLUOROBENZENE 99.9%

PERFLUOROBENZENE

Perfluorobenzene 99%

Hexafluorobenzene,99+%

Hexafluorobenzene,min.99%

Hexafluorobenzene, min. 99%

Hexaflurorobenzene

Hexafluorobenzene

Hexafluorobenzene ,98%

Hexafluorobenzene &gt

Benzene, 1,2,3,4,5,6-hexafluoro-

HEXAFLUOROBENZENE ISO 9001：2015 REACH

HEXAFLUOROBENZENE,392-56-3

392-56-3

C6F6

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