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Fmoc-L-citrulline

Product Name
Fmoc-L-citrulline
CAS No.
133174-15-9
Chemical Name
Fmoc-L-citrulline
Synonyms
FMOC-CIT-OH;FMOC-L-CIT-OH;FMOC-CITRULLINE;FMOC-L-CITRULLINE;FMOC-D-ORN(CONH2)-OH;Nα-Fmoc-L-citrulline;FMOC-ORN(CARBAMOYL)-OH;Fmoc-L-citrulline - 5 g;Fmoc-L-Orn(carbamoyl)-OH;N-ALPHA-FMOC-L-CITRULLINE
CBNumber
CB7170261
Molecular Formula
C21H23N3O5
Formula Weight
397.42
MOL File
133174-15-9.mol
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Fmoc-L-citrulline Property

Boiling point:
671.5±55.0 °C(Predicted)
Density 
1.316±0.06 g/cm3(Predicted)
refractive index 
-10 ° (C=1, DMF)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Solid
pka
3.84±0.21(Predicted)
color 
White to Almost white
BRN 
7780987
Major Application
peptide synthesis
InChIKey
NBMSMZSRTIOFOK-SFHVURJKSA-N
SMILES
NC(=O)NCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
CAS DataBase Reference
133174-15-9(CAS DataBase Reference)
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Safety

WGK Germany 
3
10
HazardClass 
IRRITANT
HS Code 
29242990
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52025
Product name
Fmoc-Cit-OH
Purity
Novabiochem?
Packaging
1g
Price
$33.8
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52025
Product name
Fmoc-Cit-OH
Purity
Novabiochem?
Packaging
5G
Price
$141
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52025
Product name
Fmoc-Cit-OH
Purity
Novabiochem?
Packaging
25g
Price
$555
Updated
2025/07/31
Sigma-Aldrich
Product number
47518
Product name
Fmoc-Cit-OH
Purity
≥97.0% (HPLC)
Packaging
5G
Price
$185
Updated
2025/07/31
TCI Chemical
Product number
F0626
Product name
Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-citrulline
Purity
>98.0%(HPLC)
Packaging
1g
Price
$23
Updated
2025/07/31
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Fmoc-L-citrulline Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

L-citrulline (1.1 equiv.) and sodium bicarbonate (2.2 equiv.) were stirred in water (0.2 M) at room temperature for 1.0h, then ethylene glycol dimethyl ether was added to the above (dimethyl ether:water= 1:1, total concentration of 0.1 M) reaction mixture, and then Fmoc-Cl (1.0 equiv.) was added, and the reaction was stirred at room temperature for 24.0h, the solvent dimethyl ether was removed under reduced pressure . The aqueous solution was extracted three times with ethyl acetate. The aqueous phase was acidified with 2M HCl (pH=1) to form a white precipitate. 10% iPrOH-EtOAc was added to the precipitate in water and stirred well to dissolve all the white precipitate in the organic solvent. The organic phase was collected and the aqueous layer was further extracted 2 times with the same 10% iPrOH-EtOAc solvent. The collected organic phase was dried over sodium sulfate. The solvent was evaporated under reduced pressure to give a clear viscous liquid. Ultrasonication with ether gave the white solid powder product Fmoc-L-citrulline, the white solid was further dried under vacuum in 96% yield.

Fmoc-L-citrulline Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-L-citrulline Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11034
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9888
Advantage
59
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View Lastest Price from Fmoc-L-citrulline manufacturers

Career Henan Chemical Co
Product
Fmoc-L-citrulline 133174-15-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-15

133174-15-9, Fmoc-L-citrullineRelated Search:


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