ChemicalBook > CAS DataBase List > (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT

(R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT

Product Name: (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT
CAS No.: 13613-65-5
Chemical Name: (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT
Synonyms: BHB Na;KTX 0101;[R]-3-Hydroxbutanoic acid;SODIUM D-3-HYDROXYBUTYRATE;SodiuM D-β-Hydroxybutyrate;sodiuM(R)-3-hydroxybutanoate;(R)-3-hydroxybutyrate sodium;Sodium (R)-3-hydroxybutyrate;optical purity ee: 99% (GLC);D-(-)-beta-Hydroxybutyricacid
CBNumber: CB7172553
Molecular Formula: C4H9NaO3
Formula Weight: 128.1
MOL File: 13613-65-5.mol

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(R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT Property

Melting point:: 149-155 °C(lit.)
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
optical activity: [α]22/D 14°, c = 10 in H2O
Water Solubility: Water: 100 mg/mL (793.08 mM)
BRN: 6118796
Stability:: Hygroscopic
InChI: InChI=1/C4H8O3.Na.H/c1-3(5)2-4(6)7;;/h3,5H,2H2,1H3,(H,6,7);;/t3-;;/s3
InChIKey: DIKSWKJUJFMKBT-LPWWCTNINA-N
SMILES: C(C(=O)O)[C@H](O)C.[NaH] |&1:4,r|

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 3-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 298360
Product name: (R)-(?)-3-Hydroxybutyric acid sodium salt
Purity: optical purity ee: 99% (GLC)
Packaging: 1g
Price: $169
Updated: 2025/07/31

TRC

Product number: H833025
Product name: (R)-(?)-3-Hydroxybutyric acid sodium salt
Packaging: 5g
Price: $240
Updated: 2021/12/16

Matrix Scientific

Product number: 090453
Product name: Sodium (R)-3-hydroxybutanoate
Purity: 95+%
Packaging: 1g
Price: $171
Updated: 2021/12/16

ChemScene

Product number: CS-W016567
Product name: (R)-3-Hydroxybutanoicacid(sodium)
Purity: ≥97.0%
Packaging: 1g
Price: $38
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0004710
Product name: (R)-(-)-3-HYDROXYBUTYRIC ACID SODIUM
Purity: 95.00%
Packaging: 1G
Price: $255.15
Updated: 2021/12/16

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(R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT Chemical Properties,Usage,Production

Chemical Properties

mp 165-167°C

Uses

chiral synthon

Uses

(R)-(-)-3-Hydroxybutyric acid sodium salt reacts with crown ether to form a supramolecular complex, which can catalyze the regioselective ring-opening polymerization of (S)-butyrolactone to form (R)-3-hydroxybutyrate oligomers (OHBs).

Uses

Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems.

Synthesis

3976-69-0

13613-65-5

In a 500 mL three-necked flask, methyl (R)-3-hydroxybutyrate (76.0 g) made from Example 1 was added, followed by 300 mL of water. The reaction temperature was controlled to be below 30 °C, and sodium hydroxide (25.8 g) was added slowly in batches over a period of 3 hours. After addition, maintain the temperature no higher than 10°C and continue to stir the reaction for 3 hours until the reaction is complete. Add 0.3 g of activated carbon and filter after continuous stirring for 0.5 hours. The filtrate was concentrated to 100 mL, at which time a large amount of solid precipitated. Crystallization was stirred at room temperature for 1 hour, centrifuged and dried in vacuum to obtain 68.9 g of (R)-(-)-3-hydroxybutyric acid sodium salt as a white solid with a yield of 85.0% and an ee value of 91.5%.

References

[1] Patent: CN107162893, 2017, A. Location in patent: Paragraph 0042; 0043

(R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: (R)-3-Hydroxybutanoic acid sodium 13613-65-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT 13613-65-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-29

Baoji Guokang Healthchem Co., Ltd.

Product: R)-(-)-3-Hydroxybutyric Acid, Sodium Salt 13613-65-5
Price: US $130.00/KG
Min. Order: 5Kg/Bag
Purity: 99%
Supply Ability: 1000KG
Release date: 2021-06-04

13613-65-5, (R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALTRelated Search:

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sodiuM(R)-3-hydroxybutanoate

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sodiuM (3R)-3-hydroxybutanoate

(3R)-3-Hydroxybutanoic Acid SodiuM Salt

(R)-3-Hydroxybutanoic Acid MonosodiuM Salt

(R)-3-Hydroxybutanoic Acid Sodium Salt

Natural (R)-3-Hydroxybutanoic Acid Sodium Salt

(R)-(-)-3-Hydroxybutyric acid sodiuM salt optical purity ee: 99% (GLC)

[R]-3-HYDROXBUTANOIC ACID SODIUM SALT

(R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT

(R)-3-HYDROXYBUTYRIC ACID SODIUM SALT

(R)-(-)-SODIUM- 3-HYDROXYBUTYRATE

(R)-(-)-3-HydroxyButyric Acid Sodium

(R)-3-hydroxybutyrate sodium

D-(-)-3-Hydroxybutyric Acid MonosodiuM Salt

KTX 0101

SodiuM D-β-Hydroxybutyrate

D-(-)-BETA-HYDROXYBUTYRIC ACID SODIUM SALT

(R)-()-3-Hydroxyisobutyric acid Sodium salt

(R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SA

Sodium (R)-3-hydroxybutyrate

D-(-)-beta-Hydroxybutyricacid

(R)-(-)-3-Hydroxybutyric acid sodium saL

(R)-(-)-3-HYDROXYBUTYRIC ACID, SODIUM SALT Basic information

(R)-3-Hydroxybutanoic acid sodium

(R)-3-Hydroxybutyric Acid,Sadium Salt

optical purity ee: 99% (GLC)

(R)-3-Hydroxybutanoic acid sodium ((R)-3-Hydroxybutyric acid)

D-3-Hydroxybutyrate sodium salt

BHB Na

Sodium D-Beta Hydroxybutyrate(D-BHB Na)

(<i>R</i>)-(?)-3-Hydroxybutyric acid sodium salt

D-3-HYDROXYBUTYRIC SODIUM SALT

13613-65-5

C4H7O3Na

Organic Building Blocks

Asymmetric Synthesis

Chiral Building Blocks

Carboxylic Acid Salts

Aliphatics

Chiral Reagents

Chiral Alcohols