(2R,3S)-N-Benzoyl-3-phenyl Isoserine

Product Name: (2R,3S)-N-Benzoyl-3-phenyl Isoserine
CAS No.: 132201-33-3
Chemical Name: (2R,3S)-N-Benzoyl-3-phenyl Isoserine
Synonyms: taxol side chain;TAXOL(R) SIDE CHAIN;Paclitaxel Impurity 30;Paclitaxel Impurity N1;Taxol side chain alcohol;TAXOL SIDE CHAIN ACID(SH);SIDE CHAINS OF PACLITAXEL--4;(2R,3S)-3-Benzoylamino-2-Hydro;(2R,3S)-N-Benzoylphenylisoserine;Paclitaxel Side Chain Impurity 1
CBNumber: CB7172977
Molecular Formula: C16H15NO4
Formula Weight: 285.3
MOL File: 132201-33-3.mol

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(2R,3S)-N-Benzoyl-3-phenyl Isoserine Property

Melting point:: 169-172 °C (lit.)
Boiling point:: 580.7±50.0 °C(Predicted)
Density: 1.316±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Acetonitrile (Slightly), DMSO (Slightly), Ethanol (Slightly)
form: Solid
pka: 3.40±0.17(Predicted)
color: White to Off-White
optical activity: [α]20/D 40°, c = 1.0 in ethanol
CAS DataBase Reference: 132201-33-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 444375
Product name: N-Benzoyl-(2R,3S)-3-phenylisoserine
Purity: 98%
Packaging: 500mg
Price: $351
Updated: 2024/03/01

TRC

Product number: B208550
Product name: (2R,3S)-N-Benzoyl-3-phenylIsoserine
Packaging: 1g
Price: $360
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB151111
Product name: N-Benzoyl-(2R,3S)-3-amino-2-hydroxy-3-phenyl-propionicacid
Packaging: 1g
Price: $539
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 43642
Product name: (2R,3S)-N-Benzoyl-3-phenylIsoserine
Packaging: 100mg
Price: $620
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB151111
Product name: N-Benzoyl-(2R,3S)-3-amino-2-hydroxy-3-phenyl-propionicacid
Packaging: 250mg
Price: $177.5
Updated: 2021/12/16

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(2R,3S)-N-Benzoyl-3-phenyl Isoserine Chemical Properties,Usage,Production

Uses

(2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity.

Uses

The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,3S)-N-Benzoyl-3-phenyl Isoserine Suppliers

Canada 1 China 110 China Hong Kong 1 Germany 1 India 4 Switzerland 1 United Kingdom 3 United States 20 Global 141

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View Lastest Price from (2R,3S)-N-Benzoyl-3-phenyl Isoserine manufacturers

Honest Joy Holdings Limited

Product: N-Benzoyl-(2R,3S)-3-phenylisoserine 132201-33-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.0%
Supply Ability: 100 tons
Release date: 2022-01-25

Career Henan Chemical Co

Product: (2R,3S)-N-Benzoyl-3-phenyl Isoserine 132201-33-3
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg , 5kg, 50kg
Release date: 2020-01-17

132201-33-3, (2R,3S)-N-Benzoyl-3-phenyl IsoserineRelated Search:

CHLOROPHOSPHONAZO III BENZOYL ISOCYANATE Benzoyl peroxide L-Homoserine Citric acid L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE 3-(4-Hydroxyphenyl)propionic acid Folic acid Benzoyl chloride Ethyl 2-(Chlorosulfonyl)acetate D-Cycloserine 3,4'-DIAMINODIPHENYLMETHANE L(+)-Lactic acid β-Alanine DL-Serine N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE METHYL ESTER 7-Epitaxol 10-Deacetylbaccatin III

N-BENZOYL-(2R,3S)-3-AMINO-2-HYDROXY-3-PHENYL-PROPIONIC ACID

N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE

TAXOL(R) SIDE CHAIN

(2R,3S)-3-Benzoylamino-2-Hydro

(2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionacid

Taxol side chain alcohol

(2R, 3S)-3-BENZOYLAMINO-2-HYDROXY-3-PHENYLPROPIONACID,98+%

(2R,3S)-3-Benzoylamino-2-hydroxy-3-phenylpropionic acid

SIDE CHAINS OF PACLITAXEL--4

(2R,3S)-2-Hydroxy-3-(benzoylamino)-3-phenylpropionic acid

(2R,3S)-3-(Benzoylamino)-3-phenyl-2-hydroxypropanoic acid

(2R,3S)-N-Benzoylphenylisoserine

(2R,3S)-N-Benzoyl-3-phenyl Isoserine

(2R,3S)-N-Benzoyl-3-phenylisoserine

(2R,3S)-3-(benzoylaMino)-2-hydroxy-3-phenylpropanoate

N-benzoyl-(3S,2R)-3-phenylisoserine

(αR,βS)-β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid

[R-(R*,S*)]-β-(benzoylaMino)-α-hydroxybenzenepropanoic Acid

(2R,3S)-3-BenzaMido-2-hydroxy-3-phenylpropanoic acid

N-Benzoyl-(2R,3S)-3-phenylisoserine (2R,3S)-3-Benzoylamino-2-hydroxy-3-phenylpropionic acid

N-Benzoyl-(2R,3S)-3-phenylisoserine 98%

TAXOL SIDE CHAIN ACID(SH)

Paclitaxel Side Chain Impurity 1

Paclitaxel Impurity 30

taxol side chain

Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (αR,βS)-

(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoic Acid ((2R,3S)-N-Benzoyl-3-phenylisoserine)

N-Benzoyl-(2R，3S)-3-phenylisoserine，taxol side chain

Paclitaxel Impurity N1

132201-33-3

132201-33-2

C6H5CONHCHC6H5CHOHCO2H

Unnatural Amino Acid Derivatives

Serine Derivatives

Specialty Synthesis

Peptide Synthesis

Herb extract

Serine Derivatives

Peptide Synthesis

Unnatural Amino Acid Derivatives

Amino Acids & Derivatives

Anti-virals

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals