(2R,3S)-N-Benzoyl-3-phenyl Isoserine
- Product Name
- (2R,3S)-N-Benzoyl-3-phenyl Isoserine
- CAS No.
- 132201-33-3
- Chemical Name
- (2R,3S)-N-Benzoyl-3-phenyl Isoserine
- Synonyms
- taxol side chain;TAXOL(R) SIDE CHAIN;Paclitaxel Impurity 30;Paclitaxel Impurity N1;Taxol side chain alcohol;TAXOL SIDE CHAIN ACID(SH);SIDE CHAINS OF PACLITAXEL--4;(2R,3S)-3-Benzoylamino-2-Hydro;(2R,3S)-N-Benzoylphenylisoserine;Paclitaxel Side Chain Impurity 1
- CBNumber
- CB7172977
- Molecular Formula
- C16H15NO4
- Formula Weight
- 285.3
- MOL File
- 132201-33-3.mol
(2R,3S)-N-Benzoyl-3-phenyl Isoserine Property
- Melting point:
- 169-172 °C (lit.)
- Boiling point:
- 580.7±50.0 °C(Predicted)
- Density
- 1.316±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Acetonitrile (Slightly), DMSO (Slightly), Ethanol (Slightly)
- form
- Solid
- pka
- 3.40±0.17(Predicted)
- color
- White to Off-White
- optical activity
- [α]20/D 40°, c = 1.0 in ethanol
- CAS DataBase Reference
- 132201-33-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 444375
- Product name
- N-Benzoyl-(2R,3S)-3-phenylisoserine
- Purity
- 98%
- Packaging
- 500mg
- Price
- $351
- Updated
- 2024/03/01
- Product number
- B208550
- Product name
- (2R,3S)-N-Benzoyl-3-phenylIsoserine
- Packaging
- 1g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- FB151111
- Product name
- N-Benzoyl-(2R,3S)-3-amino-2-hydroxy-3-phenyl-propionicacid
- Packaging
- 1g
- Price
- $539
- Updated
- 2021/12/16
- Product number
- 43642
- Product name
- (2R,3S)-N-Benzoyl-3-phenylIsoserine
- Packaging
- 100mg
- Price
- $620
- Updated
- 2021/12/16
- Product number
- FB151111
- Product name
- N-Benzoyl-(2R,3S)-3-amino-2-hydroxy-3-phenyl-propionicacid
- Packaging
- 250mg
- Price
- $177.5
- Updated
- 2021/12/16
(2R,3S)-N-Benzoyl-3-phenyl Isoserine Chemical Properties,Usage,Production
Uses
(2R,3S)-N-Benzoyl-3-phenylisoserine is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine shows cytotoxic, antiviral and immunomodulatory activity.
Uses
The presence of this chiral side chain has proven to be essential for the biological activity of taxol, one of the most promising anticancer agents being investigated. The challenging synthesis of taxol has stimulated interest in the attachment of the C-13 side chain to naturally derived taxanes like baccatin III.
(2R,3S)-N-Benzoyl-3-phenyl Isoserine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (2R,3S)-N-Benzoyl-3-phenyl Isoserine manufacturers
- Product
- N-Benzoyl-(2R,3S)-3-phenylisoserine 132201-33-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.0%
- Supply Ability
- 100 tons
- Release date
- 2022-01-25
- Product
- (2R,3S)-N-Benzoyl-3-phenyl Isoserine 132201-33-3
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg , 5kg, 50kg
- Release date
- 2020-01-17