2,3-Dimethylmaleic anhydride Property

Melting point:

93-96 °C (lit.)

Boiling point:

223 °C (lit.)

Density 

1.107 g/cm3 (100℃)

refractive index 

1.5627 (estimate)

Flash point:

222-223°C

storage temp. 

Store below +30°C.

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Solid

color 

White to Off-White

Water Solubility 

Soluble in ethanol, ether and chloroform. Slightly soluble in water.

Sensitive 

Moisture Sensitive

BRN 

112044

LogP

0.183 (est)

CAS DataBase Reference

766-39-2(CAS DataBase Reference)

NIST Chemistry Reference

2,5-Furandione, 3,4-dimethyl-(766-39-2)

EPA Substance Registry System

2,5-Furandione, 3,4-dimethyl- (766-39-2)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

22

Safety Statements 

45-36/37/39-28A-26

WGK Germany 

3

RTECS 

ON4025000

F 

9-21

TSCA 

Yes

HS Code 

2917 19 80

Hazardous Substances Data

766-39-2(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

2,3-Dimethylmaleic anhydride Chemical Properties,Usage,Production

Chemical Properties

white to beige crystals or cryst. powder

Uses

2,3-Dimethylmaleic anhydride can be usually used in the synthesis of maleimides and as an amino group protecting agent for superoxide dismutase. It is also used in the preparation of dimethylmaleic acid dimethyl ester. Further, it serves as a reactant in the dissociation of ribosomal proteins. In addition to this, The isolated molecule 2, 3-dimethylmaleic anhydride showed potent insecticidal activity in fumigation bioassay against several insect species, viz., adults of houseflies, cockroaches and stored-product insects.

Definition

ChEBI: 2,3-Dimethylmaleic anhydride is a butenolide. It is a 5-membered cyclic anhydride with a double bond between carbon atoms C2 and C3. The double bond locks the molecule in a planar conformation and stabilizes the acid anhydride against hydration. It was used as linker to a cell penetrating peptidebased nanoparticle.

Safety Profile

Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also ANHYDRIDES.

Purification Methods

Distil the anhydride from *benzene/ligroin and sublime in a vacuum. [Beilstein 17/11 V 69.]